{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T23:54:32Z","timestamp":1773100472080,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,12,10]],"date-time":"2023-12-10T00:00:00Z","timestamp":1702166400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To report a single\u2010centre experience of a complete transition from transrectal (TR) to transperineal (TP) prostate biopsy under local anaesthesia using a freehand cognitive coaxial approach and without use of antibiotic prophylaxis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>Analysis was performed of a prospective database of patients undergoing prostate biopsy performed by four surgeons between 1 June 2018 and 31 May 2022. Outcomes of interest were complications, cancer detection rate, inter\u2010operator reliability, and tolerability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, 1915 patients underwent 2337 separate prostate biopsy sessions. Only 2.4% patients in the TP group received antibiotic prophylaxis, while 100% received antibiotics in the TR group. The complication rate was significantly lower in the TP group compared to the TR group (0.3% vs 5.0%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). In contrast to the TR group, there were no cases of urosepsis or admissions to intensive care in the TP group. The total cancer detection rate by TP biopsy was 70% and the overall pathology detection rate was 88.4%. There was no difference in cancer or pathology detection between operators. A stable level of cancer detection was reached early on for both Prostate Imaging\u2010Reporting and Data System 4 and 5 lesions. All cases performed were performed successfully without need for early termination.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Implementing a complete transition from TR to TP biopsy can result in a significant reduction in complications and hospital re\u2010admissions. A cognitive freehand coaxial technique is well tolerated by patients and achieves a high cancer detection rate.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.16237","type":"journal-article","created":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T17:54:20Z","timestamp":1701107660000},"page":"324-331","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Transitioning from transrectal to transperineal prostate biopsy using a freehand cognitive approach"],"prefix":"10.1111","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0420-2585","authenticated-orcid":false,"given":"Alfred","family":"Honor\u00e9","sequence":"first","affiliation":[{"name":"Department of Urology Haukeland University Hospital  Bergen Norway"},{"name":"Department of Clinical Medicine University of Bergen  Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian Arvei","family":"Moen","sequence":"additional","affiliation":[{"name":"Department of Urology Haukeland University Hospital  Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Julieb\u00f8\u2010Jones","sequence":"additional","affiliation":[{"name":"Department of Urology Haukeland University Hospital  Bergen Norway"},{"name":"Department of Clinical Medicine University of Bergen  Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars Anders Rokne","family":"Reis\u00e6ter","sequence":"additional","affiliation":[{"name":"Department of Radiology Haukeland University Hospital  Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karsten","family":"Gravdal","sequence":"additional","affiliation":[{"name":"Department of Pathology Haukeland University Hospital  Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adeel Asghar","family":"Chaudhry","sequence":"additional","affiliation":[{"name":"Department of Urology Haukeland University Hospital  Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravi","family":"Rawal","sequence":"additional","affiliation":[{"name":"Department of Urology Haukeland University Hospital  Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrine","family":"Sand\u00f8y","sequence":"additional","affiliation":[{"name":"Department of Urology Haukeland University Hospital  Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3216-4937","authenticated-orcid":false,"given":"Christian","family":"Beisland","sequence":"additional","affiliation":[{"name":"Department of Urology Haukeland University Hospital  Bergen Norway"},{"name":"Department of Clinical Medicine University of Bergen  Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,12,10]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268815002885"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/21681805.2021.1933169"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22593"},{"key":"e_1_2_8_5_1","unstructured":"Professionals SO.Uroweb. 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