{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T15:26:54Z","timestamp":1793114814478,"version":"4.5.0"},"reference-count":39,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T00:00:00Z","timestamp":1709078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess the impact of urinary incontinence (UI) on health outcomes over the entire spectrum of acute stroke severity (National Institutes of Health Stroke Scale [NIHSS] scores: 0\u201342), due to a paucity of data on patients with milder strokes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>Data were prospectively collected (2014\u20132016) from the Sentinel Stroke National Audit Programme (1593 men, 1591 women; mean [SD] age 76.8\u2009[13.3]\u2009years) admitted to four UK hyperacute stroke units (HASUs). Relationships between variables were assessed by multivariable logistic regression. Data were adjusted for age, sex, comorbidities, pre\u2010stroke disability and intra\u2010cranial haemorrhage, and presented as odds ratios with 95% confidence intervals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Amongst patients with no symptoms or a minor stroke (NIHSS scores of 0\u20134), compared to patients without UI, patients with UI had significantly greater risks of poor outcomes including: in\u2010hospital mortality; disability at discharge; in\u2010hospital pneumonia; urinary tract infection within 7\u2009days of admission; prolonged length of stay on the HASU; palliative care by discharge; activity of daily living (ADL) support, and new discharge to care home. In patients with more moderate stroke (NIHSS score of 5\u201315) the same outcomes were identified; being at greater risk for patients with UI, except for palliative care by discharge and ADL support. With the highest stroke severity group (NIHSS score of 16\u201348) all outcomes were identified except in\u2010patient mortality, pneumonia, and ADL support. However, odds ratios diminished as NIHSS scores increased.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Urinary incontinence is a useful indicator of poor short\u2010term outcomes in older patients with an acute stroke, but irrespective of stroke severity. This provides valuable information to healthcare professionals to identify at\u2010risk individuals.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.16320","type":"journal-article","created":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T00:53:26Z","timestamp":1709168006000},"page":"604-613","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Urinary incontinence indicates mortality, disability, and infections in hospitalised stroke patients"],"prefix":"10.1111","volume":"133","author":[{"given":"Christopher H.","family":"Fry","sequence":"first","affiliation":[{"name":"School of Physiology, Pharmacology and Neuroscience University of Bristol  Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Fluck","sequence":"additional","affiliation":[{"name":"Faculty of Medical Sciences The Medical School, Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan","family":"Affley","sequence":"additional","affiliation":[{"name":"Department of Stroke Ashford and St Peter's NHS Foundation Trust  Chertsey UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puneet","family":"Kakar","sequence":"additional","affiliation":[{"name":"Department of Stroke Epsom and St Helier University Hospitals  Epsom UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pankaj","family":"Sharma","sequence":"additional","affiliation":[{"name":"Institute of Cardiovascular Research Royal Holloway University of London  Egham UK"},{"name":"Department of Clinical Neuroscience Imperial College Healthcare NHS Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Fluck","sequence":"additional","affiliation":[{"name":"Department of Cardiology Ashford and St Peter's NHS Foundation Trust  Chertsey UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2570-0938","authenticated-orcid":false,"given":"Thang S.","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Ashford and St Peter's NHS Foundation Trust  Chertsey UK"},{"name":"Institute of Cardiovascular Research Royal Holloway University of London  Egham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2,28]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2015.266"},{"key":"e_1_2_13_3_1","first-page":"132","volume-title":"Incontinence","author":"Fry CH","year":"2023"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/9781439807217-110"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mpsur.2020.01.013"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afm196"},{"key":"e_1_2_13_7_1","unstructured":"Stroke Association.Bladder and bowel problems. 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SSNAP.2017Available at:https:\/\/www.strokeaudit.org\/Documents\/National\/Clinical\/AprJul2017\/AprJul2017\u2010PublicReport.aspx. Accessed 11 Nov 2023"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-019-03901-8"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0261-5614(03)00098-0"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/ncp.10790"},{"key":"e_1_2_13_21_1","unstructured":"National Institute for Health and Care Excellence.Urinary incontinence in neurological disease: assessment and management Clinical guideline [CG148].2012Last updated: 02 October 2023. Available at:https:\/\/www.nice.org.uk\/guidance\/cg148\/resources\/urinary\u2010incontinence\u2010in\u2010neurological\u2010disease\u2010assessment\u2010and\u2010management\u2010pdf\u201035109577553605. 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