{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T12:31:03Z","timestamp":1790771463786,"version":"4.1.0"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T00:00:00Z","timestamp":1709856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To investigate the ability of propolis\u2010coated ureteric stents to solve complications, especially urinary tract infections (UTIs) and crusting, in patients with long\u2010term indwelling ureteric stents through antimicrobial and anti\u2010calculus activities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      Polyurethane (PU) ureteric stents were immersed in the ethanol extract of propolis (EEP), a well\u2010known antimicrobial honeybee product, and subjected to chemical, hydrophilic, and seismic tests. The antimicrobial activity of the EEP coating was then examined by\n                      <jats:italic>in vitro<\/jats:italic>\n                      investigation.\n                      <jats:italic>Proteus mirabilis<\/jats:italic>\n                      infection was induced in rats within uncoated and EEP\u2010coated groups, and the infection, stone formation, and inflammation were monitored at various time points.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The characterisation results showed that the hydrophilicity and stability of the EEP surface improved.\n                      <jats:italic>In vitro<\/jats:italic>\n                      tests revealed that the EEP coating was biocompatible, could eliminate &gt;90% of bacteria biofilms attached to the stent and could maintain bacteriostatic properties for up to 3\u2009months. The\n                      <jats:italic>in vivo<\/jats:italic>\n                      experiment revealed that the EEP\u2010coating significantly reduced the amount of bacteria, stones, and salt deposits on the surface of the ureteric stents and decreased inflammation in the host tissue.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Compared with clinically used PU stents, EEP\u2010coated ureteric stents could better mitigate infections and prevent encrustation. Thus, this study demonstrated that propolis is a promising natural dressing material for ureteric stents.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.16326","type":"journal-article","created":{"date-parts":[[2024,3,9]],"date-time":"2024-03-09T00:45:41Z","timestamp":1709945141000},"page":"72-80","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["<i>In vitro<\/i>\n                    and\n                    <i>in vivo<\/i>\n                    study of antibacterial and anti\u2010encrustation coating on ureteric stents"],"prefix":"10.1111","volume":"134","author":[{"given":"Yue","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Urology and Pelvic Surgery and Andrology, West China School of Public Health and West China Fourth Hospital Sichuan University  Chengdu Sichuan China"},{"name":"Department of Public Health Laboratory Sciences, West China School of Public Health and West 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