{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T22:13:21Z","timestamp":1781302401977,"version":"3.54.1"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T00:00:00Z","timestamp":1711065600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the effect of detrusor underactivity (DUA) on the postoperative outcomes of holmium laser enucleation of the prostate (HoLEP) in patients with benign prostatic hyperplasia (BPH).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>\n                      Patients with BPH who underwent HoLEP between January 2018 and December 2022 were enrolled in this prospective database study. Patients were divided into DUA (bladder contractility index [BCI] &lt;100) and non\u2010DUA (BCI \u2265100) groups. Objective (maximum urinary flow rate [Q\n                      <jats:sub>max<\/jats:sub>\n                      ], post\u2010void residual urine volume [PVR]) and subjective outcomes (International Prostate Symptom Score [IPSS], Overactive Bladder Symptom Score [OABSS], satisfaction with treatment question [STQ], overall response assessment [ORA], and willingness to undergo surgery question [WUSQ]) were compared between the two groups before surgery, and at 3 and 6\u2009months after HoLEP.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 689 patients, with a mean (standard deviation [SD]) age of 69.8\u2009(7.1)\u2009years, were enrolled. The mean (SD) BCI in the non\u2010DUA (325 [47.2%]) and DUA (364 [52.8%]) groups was 123.4\u2009(21.4) and 78.6\u2009(14.2), respectively. Both objective (Q\n                      <jats:sub>max<\/jats:sub>\n                      and PVR) and subjective (IPSS, IPSS\u2010quality of life, and OABSS) outcomes after surgery significantly improved in both groups. The Q\n                      <jats:sub>max<\/jats:sub>\n                      was lower in the DUA than in the non\u2010DUA group postoperatively. At 6\u2009months postoperatively, the total IPSS was higher in the DUA than in the non\u2010DUA group. There were no significant differences in surgical complications between the two groups. Responses to the STQ, ORA, and WUSQ at 6\u2009months postoperatively demonstrated that the patients were satisfied with the surgery (90.5% in the DUA group; 95.2% in the non\u2010DUA group), their symptoms improved with surgery (95.9% in the DUA group; 100.0% in the non\u2010DUA group), and they were willing to undergo surgery again (95.9% in the DUA group; 97.9% in the non\u2010DUA group). There were no significant differences in the responses to the STQ and WUSQ between the two groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our midterm results demonstrated that patients with BPH and DUA showed minimal differences in clinical outcomes after HoLEP compared to those without DUA. The overall satisfaction was high in the DUA group.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.16346","type":"journal-article","created":{"date-parts":[[2024,3,23]],"date-time":"2024-03-23T02:32:01Z","timestamp":1711161121000},"page":"770-777","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Effect of detrusor underactivity on surgical outcomes of holmium laser enucleation of the prostate"],"prefix":"10.1111","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3818-9626","authenticated-orcid":false,"given":"Hyun Ju","family":"Jeong","sequence":"first","affiliation":[{"name":"Department of Medical Device Development Seoul National University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyomyoung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Urology Seoul National University College of Medicine, Seoul National University Hospital  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Soo","family":"Choo","sequence":"additional","affiliation":[{"name":"Department of Urology Seoul National University College of Medicine, Seoul National University Hospital  Seoul Korea"},{"name":"Seoul Metropolitan Government\u2010Seoul National University Boramae Medical Center  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Yong","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Medical Device Development Seoul National University College of Medicine  Seoul Korea"},{"name":"Department of Urology Seoul National University College of Medicine, Seoul National University Hospital  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong Jin","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Urology Seoul National University College of Medicine, Seoul National University Hospital  Seoul Korea"},{"name":"Department of Urology Seoul National University Bundang Hospital  Seongnam\u2010si South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0322-3539","authenticated-orcid":false,"given":"Seung\u2010June","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Medical Device Development Seoul National University College of Medicine  Seoul Korea"},{"name":"Department of Urology Seoul National University College of Medicine, Seoul National University Hospital  Seoul 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