{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T01:12:30Z","timestamp":1774487550896,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T00:00:00Z","timestamp":1717027200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2024,10]]},"abstract":"\n Objective<\/jats:title>\n To explore the usefulness of the \u2018differential renal length index\u2019 (iDRL) before and after pyeloplasty, as the anteroposterior diameter is commonly used to quantify hydronephrosis but inaccuracies arise due to interobserver variability, hydration status and pure intra\u2010renal dilatation.<\/jats:p>\n <\/jats:sec>\n \n Patients and Methods<\/jats:title>\n \n Prospectively collected data, from two centres, of all children undergoing pyeloplasty for isolated unilateral pelvi\u2010ureteric junction obstruction (PUJO) (2015\u20132021) were analysed. Subgroup analysis was undertaken: Group A \u2013 differential renal function (DRF) \u226540%, Group B \u2013 subnormal DRF (20\u201339%), and Group C \u2013 symptomatic. Children with structural anomalies of upper and lower urinary tract, bilateral involvement, and subnormal DRF (<20%) were excluded. All the children had a pre\u2010 and postoperative ultrasound scan and Tc99\n m<\/jats:sup>\n mercapto\u2010acetyltriglycine (MAG3) renograms. The iDRL was calculated as follows: iDRL\u2009=\u2009([\n a\u2009\u2013\u2009b]\/b<\/jats:italic>\n )\u2009\u00d7\u2009100, where \u2018\n a<\/jats:italic>\n \u2019 is the length of hydronephrotic kidney (cm) and \u2018\n b<\/jats:italic>\n \u2019 is the length of contralateral normal kidney (cm). The mean difference and standard error of mean (SEM) between the pre\u2010 and postoperative iDRL was evaluated using the paired Student's\n t<\/jats:italic>\n \u2010test, with\n P<\/jats:italic>\n \u2009<\u20090.05 considered statistically significant.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 119 children with 1\u2010year follow\u2010up were included. For the entire cohort, the mean (SEM) preoperative iDRL was 27.7\u2009(1.4) and postoperatively was 12.5\u2009(1.1), with a mean (range) DRF improvement of 54%\u2009(44\u201366%) (\n P<\/jats:italic>\n \u2009<\u20090.001). In Group A (\n n<\/jats:italic>\n \u2009=\u200997), the mean (SEM) preoperative iDRL was 26.6\u2009(1.5) and postoperatively was 13.1\u2009(1.2), with a mean (range) DRF improvement of 50%\u2009(38\u201363%) (\n P<\/jats:italic>\n \u2009<\u20090.001). In Group B (\n n<\/jats:italic>\n \u2009=\u200922), the mean (SEM) preoperative iDRL was 32.6\u2009(3.5) and postoperatively was 10.0\u2009(2.8), with a mean (range) DRF improvement of 69%\u2009(49\u201389%) (\n P<\/jats:italic>\n \u2009<\u20090.001). In Group C (\n n<\/jats:italic>\n \u2009=\u200928), the mean (SEM) preoperative iDRL was 19.9\u2009(2.3) and postoperatively was 7.7\u2009(1.9), with a mean (range) DRF improvement of 61%\u2009(38\u201385%) (\n P<\/jats:italic>\n \u2009<\u20090.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Our study identifies the iDRL as a useful measure of improvement following successful pyeloplasty. In the subgroup with DRF of >39% minimum improvement was >37%. Similar minimum DRF improvement was also noted (>37%) in hypo\u2010functioning kidneys and symptomatic PUJO.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/bju.16415","type":"journal-article","created":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T05:55:50Z","timestamp":1717048550000},"page":"578-581","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Differential renal length index: useful measure in management of isolated unilateral hydronephrosis?"],"prefix":"10.1111","volume":"134","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-0685-3850","authenticated-orcid":false,"given":"Ketaki","family":"Gharpure","sequence":"first","affiliation":[{"name":"Department of Urology Great Ormond Street Hospital for Children London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Lobo","sequence":"additional","affiliation":[{"name":"Department of Urology Great Ormond Street Hospital for Children London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meghana","family":"Bandaru","sequence":"additional","affiliation":[{"name":"Department of Urology Great Ormond Street Hospital for Children London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Navroop","family":"Johal","sequence":"additional","affiliation":[{"name":"Department of Urology Great Ormond Street Hospital for Children London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrien","family":"Verveckken","sequence":"additional","affiliation":[{"name":"Department of Urology Universitair Ziekenhuis Antwerpen (UZA) Antwerp Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"de Baets","sequence":"additional","affiliation":[{"name":"Department of Urology Universitair Ziekenhuis Antwerpen (UZA) Antwerp Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koen","family":"van Hoeck","sequence":"additional","affiliation":[{"name":"Department of Urology Universitair Ziekenhuis Antwerpen (UZA) Antwerp Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3571-0339","authenticated-orcid":false,"given":"Gunter","family":"DeWin","sequence":"additional","affiliation":[{"name":"Department of Urology Universitair Ziekenhuis Antwerpen (UZA) Antwerp Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1281-7389","authenticated-orcid":false,"given":"Abraham","family":"Cherian","sequence":"additional","affiliation":[{"name":"Department of Urology Great Ormond Street Hospital for Children London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,5,30]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2016.08.099"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2021.01.004"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2018.01.025"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2009.12.004"},{"key":"e_1_2_8_6_1","first-page":"112","article-title":"The usefulness of testicular atrophy index in the assessment of undescended testicle \u2013 preliminary report","volume":"48","author":"Niedzielski J","year":"2003","journal-title":"Rocz Akad Med Bialymst"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)57080-9"},{"key":"e_1_2_8_8_1","first-page":"2047","article-title":"The \u201cwell tempered\u201d diuretic renogram: a standard method to examine the asymptomatic neonate with hydronephrosis or hydroureteronephrosis. A report from combined meetings of The Society for Fetal Urology and members of The Pediatric Nuclear Medicine Council \u2013 The Society of Nuclear Medicine","volume":"33","author":"Conway JJ","year":"1992","journal-title":"J Nucl Med"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.14740\/jh265w"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0284185119847680"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2020.00458"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2015.03.123"}],"container-title":["BJU International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bju.16415","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T16:11:09Z","timestamp":1761754269000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/10.1111\/bju.16415"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,30]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1111\/bju.16415"],"URL":"https:\/\/doi.org\/10.1111\/bju.16415","archive":["Portico"],"relation":{},"ISSN":["1464-4096","1464-410X"],"issn-type":[{"value":"1464-4096","type":"print"},{"value":"1464-410X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,30]]},"assertion":[{"value":"2024-05-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}