{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T22:28:57Z","timestamp":1784672937122,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T00:00:00Z","timestamp":1725321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To provide current peri\u2010operative outcomes and short\u2010term complication rates for open primary retroperitoneal lymph node dissection (RPLND), with analysis of risk factors for complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>\n                      Using the Indiana University Testicular Cancer database, we performed a retrospective analysis of all patients who underwent open primary RPLND over the study period (2018\u20132021). The primary outcomes of interest were the preoperative profile of patients undergoing surgery, complication rates, and identification of risk factors associated with complications. We used chi\u2010squared, Fisher's exact and unpaired\n                      <jats:italic>t<\/jats:italic>\n                      \u2010tests in our analyses.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 165 patients were identified. The median body mass index (BMI) was 28.6 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      . Patients most often had clinical stage IIA (39%) or IIB testicular cancer (36%). The median estimated blood loss was 150\u2009mL, with no transfusions required. Higher BMI was noted in patients that sustained any complication vs those with normal recovery (34.95 vs 28 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.0042). The median length of hospital stay was 3\u2009days. The overall complication rate was low (8.48%), with two major postoperative complications, including one case of chylous ascites (0.6%), and no deaths in the 30\u2010day period. The study was limited by its retrospective design and short\u2010term follow\u2010up.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>We found that open primary RPLND has an acceptable morbidity profile, even among a predominantly overweight cohort. Low blood loss, short hospital stay, minimal chylous ascites risk, and rare major postoperative complications should be the benchmark for retroperitoneal lymph node dissection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.16506","type":"journal-article","created":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T03:03:47Z","timestamp":1725332627000},"page":"953-959","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Contemporary short\u2010term peri\u2010operative outcomes of open primary retroperitoneal lymph node dissection"],"prefix":"10.1111","volume":"134","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1302-308X","authenticated-orcid":false,"given":"Jacob D.","family":"McFadden","sequence":"first","affiliation":[{"name":"Department of Urology Indiana University School of Medicine  Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy A.","family":"Masterson","sequence":"additional","affiliation":[{"name":"Department of Urology Indiana University School of Medicine  Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5324-6475","authenticated-orcid":false,"given":"Clint","family":"Cary","sequence":"additional","affiliation":[{"name":"Department of Urology Indiana University School of Medicine  Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21708"},{"key":"e_1_2_8_3_1","unstructured":"HowladerN NooneA KrapchoMet\u00a0al.SEER cancer statistics review 1975\u20102018 National Cancer Institute Bethesda MD.https:\/\/seer.cancer.gov\/csr\/1975_2018\/ based on November 2020 SEER Data Submission. 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