{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:45:51Z","timestamp":1787013951132,"version":"build-2736575974"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T00:00:00Z","timestamp":1729468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess the comparative effectiveness of robot\u2010assisted radical cystectomy (RARC) with intracorporeal urinary diversion (ICUD) vs open radical cystectomy\u00a0(ORC) for bladder cancer (BC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>We conducted a real\u2010life monocentric study including all consecutive patients who underwent RARC with ICUD or ORC for BC at our institution from 2014 to 2023. Uni\u2010 and multivariable logistic and Cox regression analyses were used to compare perioperative, oncological and stricture outcomes between both groups by calculating odds (ORs) and hazard (HRs) ratios with their corresponding 95% confidence intervals (CIs), respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, 316 patients underwent either RARC with ICUD (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009228 [72.2%]) or ORC (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200988 [27.8%]). The perioperative benefits of RARC vs ORC included decreased risks of major blood loss (OR 0.10, 95% CI 0.04\u20130.23;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001), perioperative transfusion (OR 0.30, 95% CI 0.16\u20130.57;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001), 90\u2010day major complications (OR 0.56, 95% CI 0.29\u20130.99;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.04), and prolonged initial length of hospital stay (OR 0.20, 95% CI 0.09\u20130.35;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001), as well as more days alive and out of the hospital within 90\u2009days of surgery (OR 2.56, 95% CI 1.46\u20134.6;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.01). In addition, the use of RARC vs ORC was associated with a higher lymph node (LN) count (OR 3.35, 95% CI 1.83\u20136.30;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001), while there was no significant difference in recurrence\u2010free (HR 0.72, 95% CI 0.49\u20131.07;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.1), cancer\u2010specific (HR 0.69, 95% CI 0.43\u20131.10;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.1), overall (HR 0.76, 95% CI 0.47\u20131.20;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.3) and uretero\u2010ileal stricture\u2010free (HR 1.18, 95% CI 0.62\u20132.25;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.6) survival between both groups after a median (interquartile range) follow\u2010up of 42.3\u2009(16.4\u201373.8)\u2009months.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our real\u2010world study supports the effectiveness of RARC with ICUD vs ORC for BC. We generally observed better perioperative outcomes, as well as similar oncological\u2014except for higher LN count\u2014and uretero\u2010ileal stricture outcomes after RARC with ICUD vs ORC.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.16565","type":"journal-article","created":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T21:39:22Z","timestamp":1729546762000},"page":"517-527","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Comparative effectiveness of robot\u2010assisted radical cystectomy with intracorporeal urinary diversion vs open radical cystectomy for bladder cancer"],"prefix":"10.1111","volume":"135","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-5263-1398","authenticated-orcid":false,"given":"Pierre\u2010Etienne","family":"Gabriel","sequence":"first","affiliation":[{"name":"GRC 5, Predictive Onco\u2010Urology, APHP, Piti\u00e9\u2010Salp\u00eatri\u00e8re H\u00f4pital, Urology 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