{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T19:50:12Z","timestamp":1761767412081,"version":"build-2065373602"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T00:00:00Z","timestamp":1737676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To compare postoperative complication rates of patients with metabolic syndrome (MetS) with patients without MetS after holmium laser enucleation of the prostate (HoLEP) for management of benign prostatic hyperplasia (BPH).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>\n                      We retrospectively reviewed patients aged &gt;40\u2009years who underwent HoLEP at our institution from 2007 to 2022. Criteria for MetS were diagnoses of at least three of the following: diabetes mellitus, hypertension, hyperlipidaemia, or obesity (body mass index \u226530\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ). Uni\u2010 and multivariable logistic regression were used to compare the likelihood of immediate, 30\u2010day, and 90\u2010day complications between groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 1500 patients were included with a median (interquartile range) age of 70\u2009(65\u201376)\u2009years. Patients with MetS were more likely to develop complications at both 30 and 90\u2009days, including urinary incontinence, irritative voiding symptoms, and bleeding (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). After adjusting for potential confounders, patients with MetS had a greater than three times odds of both 30\u2010 and 90\u2010day complications compared to patients without MetS (30\u2010day adjusted odds ratio [aOR] 3.32, 95% confidence interval [CI] 2.21\u20135.01,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001; and 90\u2010day aOR 3.64, 95% CI 2.49\u20135.31,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Metabolic syndrome was associated with a three\u2010fold likelihood of 30\u2010 and 90\u2010day complications after HoLEP. This could be an important factor to consider in preoperative counselling and patient selection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.16663","type":"journal-article","created":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T03:31:54Z","timestamp":1737689514000},"page":"684-690","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Metabolic syndrome is associated with postoperative complications after holmium laser enucleation of the prostate"],"prefix":"10.1111","volume":"135","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4133-7809","authenticated-orcid":false,"given":"Victoria S.","family":"Edmonds","sequence":"first","affiliation":[{"name":"Department of Urology Mayo Clinic Arizona  Phoenix AZ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel J.","family":"Heidenberg","sequence":"additional","affiliation":[{"name":"Department of Urology Mayo Clinic Arizona  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