{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T12:41:42Z","timestamp":1784292102543,"version":"3.55.0"},"reference-count":29,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,2,26]],"date-time":"2025-02-26T00:00:00Z","timestamp":1740528000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate long\u2010term outcomes and predictive factors of urinary continence (UC) and fecal continence (FC)\u00a0after surgery for classic bladder exstrophy (CBE) using validated questionnaires.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>This study is part of the QUALEXSTRO study, a retrospective, observational, single\u2010centre cohort study assessing through questionnaires UC, FC, sexuality, fertility, and quality of life in patients treated for CBE, who were aged of at least 15\u2009years at evaluation. Herein, UC and FC were assessed using the International Consultation on Incontinence Questionnaire\u2010Urinary Incontinence Short Form (ICIQ\u2010UI SF) and the Fecal Incontinence Quality of Life Scale (FIQL), respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 63 eligible patients, 42 patients responded to the study \u00a0(response rate 66.7%). Most patients were treated using the modern staged repair exstrophy technique (88.1%) with pelvic osteotomy (95.2%). A total of 69% of patients underwent continent urinary diversion, 61.9% underwent augmentation enterocystoplasty (AEC), and 7.1% underwent bladder neck closure. Additional endourological procedures were performed in 45.2% of patients. The median (interquartile range [IQR]) age and follow\u2010up were 26 (18\u201335) years and 22\u2009(17\u201332) years, respectively. Regarding the voiding mode, 21.4% of patients were able to void spontaneously per urethra without intermittent catheterisation, while 76.2% performed clean intermittent self\u2010catheterisation (CISC). All patients who underwent AEC performed intermittent catheterisation. The median (IQR) ICIQ\u2010UI SF score was 8 (0\u201313) and was significantly better in women (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.002). A total of 13 patients (30.9%) were continent (ICIQ\u2010UI SF score\u2009=\u20090). Of these, three were able to void spontaneously per urethra, 10 used CISC, and seven underwent AEC. Most patients (66.7%) did not respond to the FIQL questionnaire since they had no concerns regarding FC.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Achieving UC depends on both initial and subsequent surgeries, with few patients able to void per urethra during adulthood. Women have better urinary outcomes than men.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.16680","type":"journal-article","created":{"date-parts":[[2025,3,2]],"date-time":"2025-03-02T00:11:44Z","timestamp":1740874304000},"page":"1018-1024","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Long\u2010term urinary outcomes in classic bladder exstrophy: results of an extensive follow\u2010up"],"prefix":"10.1111","volume":"135","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0923-1406","authenticated-orcid":false,"given":"Sarah","family":"Abdellaoui","sequence":"first","affiliation":[{"name":"Service d'Urologie P\u00e9diatrique H\u00f4pital Femme M\u00e8re Enfant, Hospices Civils de Lyon  Lyon France"},{"name":"Centre Constitutif MARVU H\u00f4pital Femme M\u00e8re\u2010Enfant, Hospices Civils de Lyon  Bron 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