{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T00:17:58Z","timestamp":1793319478167,"version":"4.5.0"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T00:00:00Z","timestamp":1742860800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To perform a systematic review and meta\u2010analysis of studies comparing indocyanine green (ICG)\u2010guided resection of ureters with the standard of care during radical cystectomy (RC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Cochrane Central Register of Controlled Trials (CENTRAL), Medical Literature Analysis and Retrieval System Online (MEDLINE) and Web of Science were searched for studies comparing ICG\u2010guided resection of ureters with the standard of care during RC. The primary outcome was the rate of uretero\u2010intestinal stenosis (UIS) per patient, secondary outcomes included the rate of UIS per ureter, major and minor complications; re\u2010interventions due to UIS, re\u2010admissions and the length of ureter resected. Data were pooled as odds ratio (OR) or mean difference with a random\u2010effects model. Risk of bias was assessed using the Risk Of Bias In Non\u2010randomised Studies of Interventions (ROBINS\u2010I) tool and the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach was used to assess certainty of evidence. The systematic review was registered prospectively via the International Prospective Register of Systematic Reviews (PROSPERO: CRD42024545516).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In all, 11 studies totalling 1339 patients were identified. ICG\u2010guided resection led to a statistically significant decrease in UIS per patient (OR 0.20, 95% confidence interval [CI] 0.07\u20130.52) and per ureter (OR 0.17, 95% CI 0.06\u20130.50). There were statistically significantly fewer major complications, re\u2010interventions due to UIS in the ICG\u2010guided group, there was no difference in minor complications and re\u2010admissions. Certainty of evidence was low.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>With low certainty of evidence, ICG\u2010guided resection of ureters lowers the rate of UIS. A standardisation of grading of UIS is needed. The time for randomised controlled trials in this setting is now.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.16707","type":"journal-article","created":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T05:18:42Z","timestamp":1743052722000},"page":"908-917","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Indocyanine\u2010guided ureter resection for radical cystectomy \u2013 a systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"135","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4209-9470","authenticated-orcid":false,"given":"Cael\u00e1n Max","family":"Haney","sequence":"first","affiliation":[{"name":"Intelligent Systems and Robotics in Urology German Cancer Research Center (DKFZ)  Heidelberg Germany"},{"name":"DKFZ Hector Cancer Institute at the University Medical Center Mannheim  Mannheim Germany"},{"name":"Department of Urology and Urosurgery, University Medical Centre Mannheim University of Heidelberg  Mannheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Studier\u2010Fischer","sequence":"additional","affiliation":[{"name":"Intelligent Systems and Robotics in Urology German Cancer Research Center (DKFZ)  Heidelberg Germany"},{"name":"DKFZ Hector Cancer Institute at the University Medical Center Mannheim  Mannheim Germany"},{"name":"Department of Urology and Urosurgery, University Medical Centre Mannheim University of Heidelberg  Mannheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark Enrik","family":"Geissler","sequence":"additional","affiliation":[{"name":"Department of Visceral, Thoracic and Vascular Surgery, Faculty of Medicine and University Hospital Carl Gustav Carus TUD Dresden University of Technology  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob","family":"Ohlmeier","sequence":"additional","affiliation":[{"name":"Department of Urology and Urosurgery, University Medical Centre Mannheim University of Heidelberg  Mannheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niklas","family":"Westhoff","sequence":"additional","affiliation":[{"name":"Department of Urology and Urosurgery, University Medical Centre Mannheim University of Heidelberg  Mannheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens\u2010Uw","family":"Stolzenburg","sequence":"additional","affiliation":[{"name":"Department of Urology University of Leipzig  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurice Stephan","family":"Michel","sequence":"additional","affiliation":[{"name":"Department of Urology and Urosurgery, University Medical Centre Mannheim University of Heidelberg  Mannheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2931-6247","authenticated-orcid":false,"given":"Karl\u2010Friedrich","family":"Kowalewski","sequence":"additional","affiliation":[{"name":"Intelligent Systems and Robotics in Urology German Cancer Research Center (DKFZ)  Heidelberg Germany"},{"name":"DKFZ Hector Cancer Institute at the University Medical Center Mannheim  Mannheim Germany"},{"name":"Department of Urology and Urosurgery, University Medical Centre Mannheim University of Heidelberg  Mannheim 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