{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T18:54:06Z","timestamp":1787943246996,"version":"build-2784847793"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,6,8]],"date-time":"2025-06-08T00:00:00Z","timestamp":1749340800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004775","name":"Natural Science Foundation of Gansu Province","doi-asserted-by":"publisher","award":["22JR11RA069"],"award-info":[{"award-number":["22JR11RA069"]}],"id":[{"id":"10.13039\/501100004775","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82160146"],"award-info":[{"award-number":["82160146"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine the quantitative impact of renal pelvic pressure (RPP) parameters on irrigation fluid absorption dynamics during mini\u2010percutaneous nephrolithotomy (mPCNL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>In this prospective observational study, 50 patients undergoing mPCNL were enrolled. Continuous synchronised RPP monitoring was performed using a calibrated pressure transduction system, while fluid absorption was quantified via a clinical grade endoscopic surgical monitor. Analytical approaches included Pearson correlation analysis and simple linear regression modelling to characterise pressure absorption dynamics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The median (interquartile range [IQR]) baseline, mean and maximum RPP values were 12.0\u2009(10.3\u201314.8) mmHg, 16.7\u2009(14.6\u201323.1) mmHg and 60.0\u2009(35.0\u201367.3) mmHg, respectively. The median (IQR) fluid absorption was 625.5\u2009(270.8\u20131296.5) mL, corresponding to an absorption rate of 838.0\u2009(385.9\u20131349.4) mL\/h. Mean RPP exhibited a significant positive correlation with absorption rate (Pearson\n                      <jats:italic>R<\/jats:italic>\n                      \u2009=\u20090.54,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001), with linear regression modelling demonstrating a 54.2\u2010mL\/h increase in absorption rate per 1\u2010mmHg rise in mean RPP (\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.29,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). Transient RPP spikes exceeding 100\u2009mmHg occurred in 9% of cases, primarily linked to access sheath obstructions from calculus migration or blood clots.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study presents the first quantitative model identifying mean RPP as a critical predictor of irrigation fluid absorption during mPCNL. Acute pressure surges driven by sheath obstruction underscore the necessity for real\u2010time RPP monitoring and optimised outflow strategies to minimise absorption\u2010related risks.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.16812","type":"journal-article","created":{"date-parts":[[2025,6,8]],"date-time":"2025-06-08T23:43:37Z","timestamp":1749426217000},"page":"529-536","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Renal pelvic pressure drives fluid absorption in mini\u2010percutaneous nephrolithotomy: a quantitative model for absorption rate"],"prefix":"10.1111","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-2524-5614","authenticated-orcid":false,"given":"Guilin","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Urology The Second Hospital of Lanzhou University  Lanzhou China"},{"name":"Gansu Province Clinical Research Center for Urinary System Disease  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luyang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Urology The Second Hospital of Lanzhou University  Lanzhou China"},{"name":"Gansu Province Clinical Research Center for Urinary System Disease  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Urology The Second Hospital of Lanzhou University  Lanzhou China"},{"name":"Gansu Province Clinical Research Center for Urinary System Disease  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangtao","family":"Bai","sequence":"additional","affiliation":[{"name":"Department of Urology The Second Hospital of Lanzhou University  Lanzhou China"},{"name":"Gansu Province Clinical Research Center for Urinary System Disease  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoran","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Urology The Second Hospital of Lanzhou University  Lanzhou China"},{"name":"Gansu Province Clinical Research Center for Urinary System Disease  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiqi","family":"He","sequence":"additional","affiliation":[{"name":"Department of Urology The Second Hospital of Lanzhou University  Lanzhou China"},{"name":"Gansu Province Clinical Research Center for Urinary System Disease  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Urology The Second Hospital of Lanzhou University  Lanzhou China"},{"name":"Gansu Province Clinical Research Center for Urinary System Disease  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teng","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Urology The Second Hospital of Lanzhou University  Lanzhou China"},{"name":"Gansu Province Clinical Research Center for Urinary System Disease  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8108-2535","authenticated-orcid":false,"given":"Hui","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Urology The Second Hospital of Lanzhou University  Lanzhou China"},{"name":"Gansu Province Clinical Research Center for Urinary System Disease  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhilong","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Urology The Second Hospital of Lanzhou University  Lanzhou China"},{"name":"Gansu Province Clinical Research Center for Urinary System Disease  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunxin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Urology The Second Hospital of Lanzhou University  Lanzhou China"},{"name":"Gansu Province Clinical Research Center for Urinary System Disease  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Mi","sequence":"additional","affiliation":[{"name":"Department of Urology The Second Hospital of Lanzhou University  Lanzhou China"},{"name":"Gansu Province Clinical Research Center for Urinary System Disease  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8140-591X","authenticated-orcid":false,"given":"Zhiping","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Urology The Second Hospital of Lanzhou University  Lanzhou China"},{"name":"Gansu Province Clinical Research Center for Urinary System Disease  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aei279"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2001.1962-3.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1089\/089277902753752160"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-6576.1999.430312.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1988.tb08483.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(79)80111-2"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-024-04835-3"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1089\/089277902761402989"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(84)90145-6"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.3126\/jssn.v24i2.42835"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1089\/end.2017.0602"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)50311-0"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000061965.51478.79"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1926.02680160035011"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.16095"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.15858"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-024-05313-6"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.21037\/tau-19-780"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1063\/5.0172756"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00219.2018"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI106667"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-018-2378-4"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.21037\/tau.2020.03.30"},{"key":"e_1_2_8_25_1","first-page":"82","article-title":"The role of intraoperative intrarenal pressure in the postoperative period of percutaneous nephrolithotripsy in patients with urolithiasis","volume":"15","author":"Khotko DN","year":"2022","journal-title":"Ecumene"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.16539"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00240-006-0069-x"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)36456-X"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.31491\/UTJ.2023.12.015"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1089\/end.2008.0001"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)64446-1"}],"container-title":["BJU International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bju.16812","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T07:55:46Z","timestamp":1761724546000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/10.1111\/bju.16812"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,8]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1111\/bju.16812"],"URL":"https:\/\/doi.org\/10.1111\/bju.16812","archive":["Portico"],"relation":{},"ISSN":["1464-4096","1464-410X"],"issn-type":[{"value":"1464-4096","type":"print"},{"value":"1464-410X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,8]]},"assertion":[{"value":"2025-06-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}