{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T14:30:42Z","timestamp":1761748242257,"version":"build-2065373602"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:00:00Z","timestamp":1750204800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100022217","name":"Flinders Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100022217","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the association of smoking with post\u2010prostatectomy functional recovery in a large population\u2010based cohort using standardised outcome measures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>We conducted a cohort study and reported findings according to the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) guidelines. We used a registry with prospectively gathered patient\u2010reported outcome measures (PROMs) regarding health and morbidity. We included all men who underwent radical prostatectomy (RP) for localised prostate cancer, without (neo)adjuvant hormone or radiotherapy treatment. In our analysis, we compared Expanded Prostate Cancer Index Composite\u201026 (EPIC\u201026) scores between people who had ever smoked and those who had not during 24\u2009months\u2019 follow\u2010up. We identified significant confounders by means of a causal directed acyclic graph, adjusted for these, and performed subgroup and sensitivity analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In total, 2676 patients were included in the analysis. PROM data were available for 61% of the total 4356 otherwise eligible participants. Multivariable regression analysis showed that patients who had ever smoked (ever smokers) scored 11 points lower for sexual function (95% confidence interval \u221215.0, \u22127.0) compared to never smokers during 24\u2009months\u2019 follow\u2010up. Subgroup analysis showed that individuals with baseline scores above 80 were more at risk of sexual function loss. Urinary incontinence scores were similar between ever smokers and never smokers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Smoking was associated with lower sexual function scores in the first 2\u2009years after RP, but not with changes in urinary incontinence outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.16817","type":"journal-article","created":{"date-parts":[[2025,6,29]],"date-time":"2025-06-29T09:55:33Z","timestamp":1751190933000},"page":"647-656","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The association of smoking with urinary and sexual function recovery following radical prostatectomy"],"prefix":"10.1111","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4549-4249","authenticated-orcid":false,"given":"Jordi","family":"Visscher","sequence":"first","affiliation":[{"name":"Flinders Health and Medical Research Institute, College of Medicine and Public Health Flinders University  Adelaide SA Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Billie","family":"Bonevski","sequence":"additional","affiliation":[{"name":"Flinders Health and Medical Research Institute, College of Medicine and Public Health Flinders University  Adelaide SA Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5038-5859","authenticated-orcid":false,"given":"Michael","family":"O'Callaghan","sequence":"additional","affiliation":[{"name":"Flinders Health and Medical Research Institute, College of Medicine and Public Health Flinders University  Adelaide SA Australia"},{"name":"Urology Unit Flinders Medical Centre  Adelaide SA Australia"},{"name":"The University of Adelaide, Discipline of Medicine  Adelaide SA Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_8_3_1","unstructured":"EAU \u2013 ESTRO \u2013 ESUR \u2013 SIOG guidelines on prostate cancer [Internet]. Available at:https:\/\/uroweb.org\/guideline\/prostate\u2010cancer\/. Accessed July 2021"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.283.3.354"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa074311"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b4817"},{"key":"e_1_2_8_7_1","unstructured":"OngWLKK BensleyJ SteeperMet\u00a0al.Prostate cancer across Australia and New Zealand PCOR\u2010ANZ 2015\u20102021 annual report 2023.2024"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21708"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1006\/pmed.2001.0830"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.5489\/cuaj.1171"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.7812\/TPP\/16-138"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwi052"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41391-023-00701-2"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m3503"},{"volume-title":"The International Statistical Classification of Diseases and Related Health Problems, Tenth Revision, Australian Modification (ICD\u201010\u2010AM)","year":"2010","author":"National Centre for Classification in Health (NCCH)","key":"e_1_2_8_15_1"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2010.01.027"},{"key":"e_1_2_8_17_1","first-page":"1887","article-title":"Robust causal inference using directed acyclic graphs: the R package \u2018dagitty\u2019","volume":"45","author":"BvdZ JT","year":"2016","journal-title":"Int J Epidemiol"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2014.08.044"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2017.03.121"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000000392"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000020162"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2005.05571.x"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-019-04058-w"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2012.05.046"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euros.2022.03.009"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2022.04.015"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000001572"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000002757"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2012.11.075"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsxm.2018.02.008"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1080\/0092623X.2011.560538"}],"container-title":["BJU International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bju.16817","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:08:36Z","timestamp":1761743316000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/10.1111\/bju.16817"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,18]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1111\/bju.16817"],"URL":"https:\/\/doi.org\/10.1111\/bju.16817","archive":["Portico"],"relation":{},"ISSN":["1464-4096","1464-410X"],"issn-type":[{"type":"print","value":"1464-4096"},{"type":"electronic","value":"1464-410X"}],"subject":[],"published":{"date-parts":[[2025,6,18]]},"assertion":[{"value":"2025-06-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}