{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:45:48Z","timestamp":1787013948480,"version":"build-2736575974"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T00:00:00Z","timestamp":1750118400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To compare perioperative, postoperative and functional outcomes between stapled (ST) and handsewn (HS) intracorporeal orthotopic neobladder (iON) configuration during robot\u2010assisted radical cystectomy (RARC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>Our single centre institutional bladder cancer dataset was queried for \u2018RARC\u2019 \u2018stapled\u2019 and \u2018handsewn\u2019 iON. Baseline, peri\u2010 and postoperative features of patients treated between January 2018 and July 2023 were collected. Continuous and categorical variables were compared using Kruskal\u2013Wallis and chi\u2010square tests. The Kaplan\u2013Meier method was applied to assess functional outcomes. Cox regression analysis was performed to identify predictors of continence recovery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, 116 patients were enrolled (HS\u2010iON, 60 patients). There were no differences in perioperative outcomes, except for the hospital length of stay, being shorter in the HS\u2010iON cohort (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). There were no differences in the 30\u2010 (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.17) and 90\u2010day (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.69) postoperative complications. The stone rate was lower in the HS\u2010iON cohort (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.01). At Kaplan\u2013Meier analysis, patients with HS\u2010iON had higher day\u2010 (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001) and night\u2010time (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001) continence recovery probabilities. At multivariable analysis, the only independent predictor of continence recovery was \u2018sex\u2010sparing approach\u2019. Excluding patients who underwent sex\u2010sparing procedures, the HS approach was the only predictor of night\u2010time continence recovery (hazard ratio 2.6, 95% confidence 1.27\u20135.34;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.009).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Hand sewing may represent a preferable option for iON configuration during RARC. ST\u2010iON did not prove to either reduce operative times or perioperative complications, while seemed to significantly impact on the risk of stone formation and continence recovery. Whenever oncologically feasible, a sex\u2010sparing approach should be preferred to improve day\u2010 and night\u2010time continence recovery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.16826","type":"journal-article","created":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T20:58:28Z","timestamp":1750193908000},"page":"866-871","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Stapled vs totally handsewn robotic intracorporeal neobladder: perioperative and functional outcomes"],"prefix":"10.1111","volume":"136","author":[{"given":"Riccardo","family":"Mastroianni","sequence":"first","affiliation":[{"name":"IRCCS \u2018Regina Elena\u2019 National Cancer Institute, Urology  Rome 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