{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T05:41:02Z","timestamp":1792129262678,"version":"4.4.0"},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the incidence of natural pregnancy (NP) and subsequent live birth following microsurgical varicocelectomy (MV) in male infertility patients with varicocele, and to identify potential predictive factors for successful outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>This prospective cohort study included 360 male infertility patients diagnosed with clinically palpable varicocele. Participants were followed for 2\u2009years after undergoing MV. The primary outcomes were NP and subsequent live birth, with secondary outcomes including miscarriage rates, infant health, and surgical complications. Cox regression analyses was applied to select predictive factors, and nomograms were constructed to establish prediction models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Within 2\u2009years after MV, 40.89% had live births following NP. Significant improvements were observed in sperm concentration, total motility, progressive motile sperm count, and morphology after MV. Multivariate Cox analysis confirmed that larger testicular volume, lower follicle\u2010stimulating hormone, and higher inhibin B were independent predictors for live birth. The nomogram incorporating these three variables demonstrated good discrimination and favourable calibration. Decision curve analysis confirmed the model's clinical utility across a wide range of threshold probabilities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings provide strong evidence to guide andrologists in counselling patients about the benefits of MV and help determine whether MV is necessary for achieving live birth in male infertility associated with varicocele.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.70194","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T15:41:31Z","timestamp":1772984491000},"page":"858-865","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A nomogram of testicular volume, follicle\u2010stimulating hormone, and inhibin B for predicting live birth after varicocelectomy"],"prefix":"10.1111","volume":"137","author":[{"given":"Hong","family":"Xiao","sequence":"first","affiliation":[{"name":"Department of Andrology and Sexual Medicine The First Affiliated Hospital of Fujian Medical University  Fuzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi\u2010lang","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Andrology and Sexual Medicine The First Affiliated Hospital of Fujian Medical University  Fuzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Andrology and Sexual Medicine The First Affiliated Hospital of Fujian Medical University  Fuzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Andrology and Sexual Medicine The First Affiliated Hospital of Fujian Medical 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