{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T21:17:42Z","timestamp":1783459062410,"version":"3.55.0"},"reference-count":18,"publisher":"Wiley","issue":"S2","license":[{"start":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T00:00:00Z","timestamp":1772928000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T00:00:00Z","timestamp":1772928000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the temporal changes in lower urinary tract symptoms (LUTS) following transurethral resection of prostate (TURP), assessed using fortnightly completion of the International Prostate Symptom Score (IPSS) as compared to baseline.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>This was a prospective observational study. Patients completed the IPSS preoperatively and at 2, 4, 6 and 8\u2009weeks postoperatively. Age, body mass index, prior TURP, resected prostate mass, histology, analgesia, symptomatic urinary tract infections (UTIs), and unplanned readmissions were also collected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 50 men were enrolled in the study with a mean (SD, range) age of 70.1\u2009(8.4, 47\u201395)\u2009years. The mean (SD) baseline IPSS was 25.5\u2009(7.9)\u2009points, indicating severe symptoms in majority of patients. Significant improvement was observed across all timepoints (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001 for all comparisons vs baseline, repeated measures analysis of variance). Irritative symptoms saw an immediate improvement at 2\u2009weeks compared to baseline, which was sustained until final follow up. Quality of life improved by 56% and was moderately correlated with frequency (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.68), weak stream (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.63) and nocturia (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.61). Both resected prostate mass and age displayed poor correlation with IPSS symptoms (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u2009\u22120.09 to \u22120.36 and 0.01 to 0.22 respectively). Analgesia (patient\u2010reported paracetamol or ibuprofen) use decreased over time to 34%, 16%, 12%, and 8% at 2, 4, 6, and 8\u2009weeks respectively. Antibiotics for UTI were given in 14% of patients, whilst 5% required re\u2010admission due to clot retention.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Contrary to common clinician expectations, LUTS did not worsen in the initial postoperative period. Quality\u2010of\u2010life scores correlated with a mixture of irritative and obstructive symptoms. These findings now quantify expected rates of improvement postoperatively and allow for further investigation into tailored interventions such as pharmacotherapy to enhance patient experience and outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.70219","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:52:39Z","timestamp":1773013959000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Natural history of lower urinary tract symptoms following transurethral resection of prostate: a prospective observational study"],"prefix":"10.1111","volume":"138","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5278-1935","authenticated-orcid":false,"given":"Alice","family":"Thomson","sequence":"first","affiliation":[{"name":"Department of Urology, Austin Health  Heidelberg, Victoria Australia"},{"name":"North Eastern Urology  Heidelberg, Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur","family":"Yim","sequence":"additional","affiliation":[{"name":"Department of Urology, Austin Health  Heidelberg, Victoria Australia"},{"name":"North Eastern Urology  Heidelberg, Victoria Australia"},{"name":"Department of Surgery University of Melbourne  Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5215-5985","authenticated-orcid":false,"given":"Kirby","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Urology, Austin Health  Heidelberg, Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damien","family":"Bolton","sequence":"additional","affiliation":[{"name":"Department of Urology, Austin Health  Heidelberg, Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Liodakis","sequence":"additional","affiliation":[{"name":"Department of Urology, Austin Health  Heidelberg, Victoria Australia"},{"name":"North Eastern Urology  Heidelberg, Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,8]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"Lower Urinary Tract Symptoms (LUTS): An International Consultation on Male LUTS","author":"Societe International d'Urologie","year":"2013"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.15098"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)36966-5"},{"key":"e_1_2_8_5_1","volume-title":"EAU guidelines on non\u2010neurogenic male lower urinary tract symptoms (LUTS)","author":"Cornu 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