{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T12:05:29Z","timestamp":1780920329067,"version":"3.54.1"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T00:00:00Z","timestamp":1774915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T00:00:00Z","timestamp":1774915200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the effect of prostate size on surgical outcomes in single\u2010port robot\u2010assisted radical prostatectomy (SP\u2010RARP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>We conducted a multicentre analysis of patients undergoing SP\u2010RARP between 2018 and 2024. Our primary endpoint was to assess the impact of prostate size on SP\u2010RARP surgical outcomes, including operating time, estimated blood loss (EBL), nerve\u2010sparing status, margin status, and intra\u2010\/postoperative complications. Logistic regression models assessed the independent impact of prostate size (calculated at final pathology) on these outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 343 patients were included; the median (interquartile range) prostate size was 46 (37\u201352)\u2009g. Of these, 114 patients had a prostate size of \u226440\u2009g, 175 of 41\u201369\u2009g, and 54 of \u226570\u2009g. Larger prostates were associated with significantly prolonged operating time (265 vs 301 vs 306\u2009min,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001), increased EBL (100 vs 100 vs 150\u2009mL,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.012), and lower nerve\u2010sparing rates (79% vs 64% vs 44%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). Non\u2010focal positive margins occurred in 23% of cases, with no significant differences across size groups (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.6), nor for intraoperative (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.2) or for postoperative complications (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&gt;\u20090.9) rates between prostate size groups. In multivariable logistic regression, prostate size remained an independent predictor of prolonged operating time above median (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.012), increased EBL above median (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.007), and lower nerve\u2010sparing (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.002). No significant association was found with margin status (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.092) or postoperative complications (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&gt;\u20090.9).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Prostate size impacts intraoperative complexity in SP\u2010RARP but does not increase complication or margin rates. These findings support the feasibility and safety of SP\u2010RARP across a broad range of prostate sizes, consistent with trends reported for multiport RARP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.70255","type":"journal-article","created":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T03:56:15Z","timestamp":1775015775000},"page":"100-107","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The impact of prostate size on single\u2010port robot\u2010assisted radical prostatectomy surgical outcomes"],"prefix":"10.1111","volume":"138","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-0273-7593","authenticated-orcid":false,"given":"Alessio","family":"Finocchiaro","sequence":"first","affiliation":[{"name":"Vattikuti Urology Institute Henry Ford Health System  Detroit MI USA"},{"name":"Department of Urology IRCCS Humanitas Research Hospital  Rozzano Italy"},{"name":"Department of Biomedical Sciences Humanitas University, Pieve Emanuele  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhannad","family":"Aljoulani","sequence":"additional","affiliation":[{"name":"Department of Urology University of Illinois at Chicago  Chicago IL USA"},{"name":"Department of Urology IRCCS Humanitas Research Hospital  Rozzano Italy"},{"name":"Department of Biomedical Sciences Humanitas University, Pieve Emanuele  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Almajedi","sequence":"additional","affiliation":[{"name":"Department of Urology Henry Ford Macomb  Clinton Township MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vigan\u00f2","family":"Silvia","sequence":"additional","affiliation":[{"name":"Vattikuti Urology Institute Henry Ford Health System  Detroit MI USA"},{"name":"Department of Clinical and Experimental Medicine, Urologic Section University of Messina  Messina Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Bertini","sequence":"additional","affiliation":[{"name":"Vattikuti Urology Institute Henry Ford Health System  Detroit MI USA"},{"name":"Division of Oncology, Unit of Urology, IRCCS Ospedale San Raffaele Vita\u2010Salute San Raffaele University  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arianna","family":"Biasatti","sequence":"additional","affiliation":[{"name":"Department of Urology Rush University Medical Center  Chicago IL USA"},{"name":"Urological Clinic, Department of Medicine, Surgery and Health Sciences University of Trieste  Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5830-0975","authenticated-orcid":false,"given":"Fabio Maria","family":"Valenzi","sequence":"additional","affiliation":[{"name":"Department of Urology University of Illinois at Chicago  Chicago IL USA"},{"name":"Urology Unit, Department of Medico\u2010Surgical Sciences and Biotechnologies, Faculty of Pharmacy and Medicine Sapienza University of Rome  Latina Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Ficarra","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, Urologic Section University of Messina  Messina Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2436-2412","authenticated-orcid":false,"given":"Gabriele","family":"Sorce","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, Urologic Section University of Messina  Messina Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0595-7165","authenticated-orcid":false,"given":"Andrea","family":"Salonia","sequence":"additional","affiliation":[{"name":"Division of Oncology, Unit of Urology, IRCCS Ospedale San Raffaele Vita\u2010Salute San Raffaele University  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Briganti","sequence":"additional","affiliation":[{"name":"Division of Oncology, Unit of Urology, IRCCS Ospedale San Raffaele Vita\u2010Salute San Raffaele University  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7267-4181","authenticated-orcid":false,"given":"Francesco","family":"Montorsi","sequence":"additional","affiliation":[{"name":"Division of Oncology, Unit of Urology, IRCCS Ospedale San Raffaele Vita\u2010Salute San Raffaele University  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Lughezzani","sequence":"additional","affiliation":[{"name":"Department of Urology IRCCS Humanitas Research Hospital  Rozzano Italy"},{"name":"Department of Biomedical Sciences Humanitas University, Pieve Emanuele  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicol\u00f2","family":"Buffi","sequence":"additional","affiliation":[{"name":"Department of Urology IRCCS Humanitas Research Hospital  Rozzano Italy"},{"name":"Department of Biomedical Sciences Humanitas University, Pieve Emanuele  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vourganti","family":"Srinivas","sequence":"additional","affiliation":[{"name":"Department of Urology Rush University Medical Center  Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Autorino","sequence":"additional","affiliation":[{"name":"Department of Urology Rush University Medical Center  Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Crivellaro","sequence":"additional","affiliation":[{"name":"Department of Urology University of Illinois at Chicago  Chicago IL 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WangZet\u00a0al.The impact of prostate volume on Retzius\u2010sparing robot\u2010assisted laparoscopic radical prostatectomy with retrograde release of the neurovascular bundle [Internet]. In Review;2024. Available at:https:\/\/www.researchsquare.com\/article\/rs\u20104914193\/v1. 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