{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T11:41:31Z","timestamp":1786966891503,"version":"build-2736575974"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,5,31]],"date-time":"2026-05-31T00:00:00Z","timestamp":1780185600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,31]],"date-time":"2026-05-31T00:00:00Z","timestamp":1780185600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the feasibility and performance of the StoneSense\u2122 module (SSM; IPG Medical, Marlborough, MA, USA), a prototype real\u2010time target recognition unit integrated into a IPG Thulium Fiber Laser (TFL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      The SSM analyses the spectral signature of back reflected light\u2010emitting diode (LED) light from the target, stopping laser energy emission when incoming signal is originating from tissue or when the fibre\u2010to\u2010target distance is larger than pre\u2010defined threshold (typically, \u22652\u20134\u2009mm). The\n                      <jats:italic>ex vivo<\/jats:italic>\n                      tests were conducted on artificial BegoStone phantoms ((Bego GmbH &amp; Co. KG, Bremen, Germany) embedded in porcine kidney tissue using energy settings of 0.1\u20132\u2009J and 5\u2013100\u2009Hz at two fibre\u2010scanning speeds (1 and 3\u2009mm\/s) through a translation stage movement. Human urinary stones were subsequently tested at 2 and 5\u2009mm\/s with setting of 0.5\u2009J\u2009\u00d7\u200920\u2009Hz. The\n                      <jats:italic>in vivo<\/jats:italic>\n                      trial was conducted by lithotripsy of pre\u2010implanted human stones in porcine urinary tract. Primary outcome measures included ablation efficiency as well as specificity and sensitivity of stone recognition.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Soft tissue ablation was completely prevented in all the\n                      <jats:italic>ex vivo<\/jats:italic>\n                      trials while maintaining high lithotripsy efficiency. Mean stone ablation reduction was 2.75% and 3% at fibre scanning speeds of 1 and 3\u2009mm\/s, respectively. The system achieved 100% sensitivity and up to 98% specificity in inhibiting laser emission to soft tissue.\n                      <jats:italic>In vivo<\/jats:italic>\n                      , complete dusting with fragments &lt;500\u2009\u03bcm was achieved for all studied stone types without observable mucosal injury. Specificity ranged from 85% to 100%, while sensitivity ranged from 90% to 100%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Integration of back reflected\u2010light\u2010spectra\u2010based laser emission control into a TFL\u2010based lithotripsy system is feasible and effective. The SSM enables precise real\u2010time stone recognition, minimises unnecessary lasing, and preserves dusting efficiency.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.70301","type":"journal-article","created":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T02:24:51Z","timestamp":1780280691000},"page":"267-275","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Pre\u2010clinical evaluation of a laser system with emission control based on stone vs soft tissue recognition"],"prefix":"10.1111","volume":"138","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2459-3803","authenticated-orcid":false,"given":"Olivier","family":"Traxer","sequence":"first","affiliation":[{"name":"Service d\u2019Urologie, AP\u2010HP H\u00f4pital Tenon  Paris France"},{"name":"Group Recherche Clinique n\u00b020, Sorbonne Universit\u00e9  Paris 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