{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T10:28:29Z","timestamp":1793788109657,"version":"4.6.1"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To examine the role of health\u2010related quality of life (HRQoL) assessments and patient\u2010reported outcome measures (PROMs) in the economic evaluation of urological interventions, highlighting methodological challenges, and identifying areas for future development.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This narrative review synthesises key frameworks for economic evaluation in urology, describes methods for utility derivation, and critically appraises the application of both generic and disease\u2010specific PROMs. Evidence is drawn from major urological trials and model\u2010based evaluations, with attention to their impact on health technology assessment decisions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Patient\u2010reported outcome measures underpin cost\u2010utility analyses across the full spectrum of urological conditions, including benign prostatic hyperplasia (BPH), urinary incontinence, overactive bladder, bladder cancer, renal cancer, and prostate cancer. Generic instruments such as the EuroQoL five Dimensions (EQ\u20105D) and 36\u2010item Short\u2010Form Health Survey (SF\u201036) facilitate cross\u2010disease comparison but may lack sensitivity to urological symptoms. Disease\u2010specific tools (e.g., International Prostate Symptom Score, Overactive Bladder Questionnaire, 26\u2010item Expanded Prostate cancer Index Composite) provide granularity but often require mapping to utility values, introducing uncertainty. Trial\u2010based evaluations (e.g., Trans European Research into the use of Management Policies for LUTS suggestive of BPH in Primary Healthcare [TRIUMPH], Single\u2010Incision Mini\u2010Slings [SIMS], Refractory Overactive Bladder: Sacral NEuromodulation vs BoTulinum Toxin Assessment [ROSETTA]) demonstrate that PROM\u2010derived quality\u2010adjusted life year differences can decisively influence cost\u2010effectiveness. Surgery\u2010related PROMs including the Consultation and Relational Empathy measure can capture important short\u2010term recovery outcomes not measured by generic tools.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Health\u2010related quality of life and PROMs are foundational to value\u2010based urological care. Accurate and context\u2010sensitive measurement ensures that cost\u2010utility analyses reflect patient experience as well as clinical outcomes. Future priorities include development of preference\u2010based urology\u2010specific PROMs, improved digital\/electronic PROM capture, validation of mapping algorithms, and integration of surgery\u2010related PROMs into economic evaluations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.70365","type":"journal-article","created":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:28:03Z","timestamp":1782883683000},"page":"750-758","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<scp>Health\u2010related quality of life<\/scp>\n                    and patient\u2010reported outcome measures in economic evaluation of urological technologies: challenges and opportunities"],"prefix":"10.1111","volume":"138","author":[{"given":"Mohammed El","family":"Bahnasawi","sequence":"first","affiliation":[{"name":"Urology Department, Freeman Hospital Newcastle University Teaching Hospitals  Newcastle Upon Tyne 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