{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T08:30:17Z","timestamp":1786437017951,"version":"build-2736575974"},"reference-count":12,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:00:00Z","timestamp":1782950400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:00:00Z","timestamp":1782950400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the incidence of venous thromboembolism (VTE) after penile cancer surgery using national hospital data and to assess current thromboprophylaxis practices across UK specialist centres.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects\/Patients and Methods<\/jats:title>\n                    <jats:p>A retrospective cohort study was conducted using Secondary Uses Service (SUS) data on penile cancer surgeries performed in NHS hospitals in England between 2015 and 2024. A national survey of UK Penile Cancer Network (UK PeCaN) surgeons was undertaken to assess current thromboprophylaxis practice. The primary outcome was symptomatic VTE within 180\u2009days of surgery, identified using International Classification of Diseases, 10th Revision (ICD\u201010) codes. Cumulative incidence of first postoperative VTE was analysed using patient\u2010level time\u2010to\u2010event methods, with censoring at second surgery, 180\u2009days or administrative end of follow\u2010up. Survey responses were summarised using descriptive statistics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In this observational population\u2010level study, 4310 patients underwent 5903 penile cancer\u2010related procedures. A total of 143 VTE episodes were recorded over the 9\u2010year period, corresponding to an overall crude incidence of 2.5%. In patient\u2010level time\u2010to\u2010event analysis, the cumulative incidence of first postoperative symptomatic VTE was 0.21% at 30\u2009days, 0.69% at 90\u2009days and 1.08% at 180\u2009days. Descriptive procedure\u2010level analyses suggested higher unadjusted VTE rates following more extensive procedures, including lymph node dissection and total penectomy, although these estimates should be interpreted cautiously because of staged procedures and unmeasured patient\u2010level confounding. Most VTE events occurred after hospital discharge. The survey, comprising 24 responses from 10 specialist centres, revealed substantial variation in thromboprophylaxis practice, with 71% of surgeons not using formal VTE risk assessment tools.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Venous thromboembolism is an important postoperative complication after penile cancer surgery, particularly after more extensive procedures and staged treatment pathways. Current prophylaxis practices are inconsistent. These findings support the further collection and analysis of disease\u2010specific and the development of procedure\u2010specific guidelines recommending extended thromboprophylaxis in high\u2010risk patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.70378","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T09:32:49Z","timestamp":1782984769000},"page":"501-507","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Venous thromboembolism after penile cancer surgery: a\n                    <scp>UK PeCaN<\/scp>\n                    study"],"prefix":"10.1111","volume":"138","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-5268-0265","authenticated-orcid":false,"given":"Aishwarya","family":"Kaur","sequence":"first","affiliation":[{"name":"Department of Urology The Christie NHS Foundation Trust  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"El\u2010Taji","sequence":"additional","affiliation":[{"name":"Department of Urology The Christie NHS Foundation Trust  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hussain","family":"Alnajjar","sequence":"additional","affiliation":[{"name":"Department of Urology University College London Hospitals NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Ayres","sequence":"additional","affiliation":[{"name":"Department of Urology St George's University Hospitals NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Christodoulidou","sequence":"additional","affiliation":[{"name":"Department of Urology University College London Hospitals NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Eardley","sequence":"additional","affiliation":[{"name":"Department of Urology Leeds Teaching Hospitals NHS Trust  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamoun","family":"Elmamoun","sequence":"additional","affiliation":[{"name":"Department of Urology Leeds Teaching Hospitals NHS Trust  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johnathan","family":"Goddard","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospitals of Leicester NHS Trust  Leicester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Gordon","sequence":"additional","affiliation":[{"name":"Department of Urology Leeds Teaching Hospitals NHS Trust  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Hadway","sequence":"additional","affiliation":[{"name":"Department of Urology University College London Hospitals NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Odunayo","family":"Kalejaiye","sequence":"additional","affiliation":[{"name":"Department of Urology North Bristol NHS Trust  Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Keegan","sequence":"additional","affiliation":[{"name":"Department of Urology Sunderland Royal Hospital  Sunderland UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivekanandan","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Urology Norfolk and Norwich University Hospitals NHS Foundation Trust  Norwich UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurice","family":"Lau","sequence":"additional","affiliation":[{"name":"Department of Urology The Christie NHS Foundation Trust  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditya","family":"Manjunath","sequence":"additional","affiliation":[{"name":"Department of Urology North Bristol NHS Trust  Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luke","family":"McGuinness","sequence":"additional","affiliation":[{"name":"Department of Urology Sunderland Royal Hospital  Sunderland UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin","family":"Mulholland","sequence":"additional","affiliation":[{"name":"Department of Urology Altnagelvin Hospital  Londonderry UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asif","family":"Muneer","sequence":"additional","affiliation":[{"name":"Department of Urology University College London Hospitals NHS Foundation Trust  London UK"},{"name":"Division of Surgery &amp; Interventional Science NIHR Biomedical Research Centre  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopoulos","family":"Panagiotis","sequence":"additional","affiliation":[{"name":"Department of Urology The Christie NHS Foundation Trust  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Randhawa","sequence":"additional","affiliation":[{"name":"Department of Urology Altnagelvin Hospital  Londonderry UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varun","family":"Sahdev","sequence":"additional","affiliation":[{"name":"Department of Urology University College London Hospitals NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chitranjan","family":"Shukla","sequence":"additional","affiliation":[{"name":"Department of Urology Western General Hospital  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Watkin","sequence":"additional","affiliation":[{"name":"Department of Urology St George's University Hospitals NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwin","family":"Sachdeva","sequence":"additional","affiliation":[{"name":"Department of Urology The Christie NHS Foundation Trust  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arie","family":"Parnham","sequence":"additional","affiliation":[{"name":"Department of Urology The Christie NHS Foundation Trust  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay","family":"Sangar","sequence":"additional","affiliation":[{"name":"Department of Urology The Christie NHS Foundation Trust  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,2]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"Cancer Research UK.Penile cancer incidence statistics.2024. Available at:https:\/\/www.cancerresearchuk.org. Accessed August 20 2024"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/2051415816676740"},{"key":"e_1_2_8_4_1","unstructured":"NHS Digital.Secondary Uses Service (SUS).2024. Available at:https:\/\/digital.nhs.uk\/services\/secondary\u2010uses\u2010service\u2010sus. Accessed August 20 2024"},{"key":"e_1_2_8_5_1","unstructured":"Manchester Cancer Research Centre.Penile cancer. Available at:https:\/\/www.mcrc.manchester.ac.uk\/impact\u2010case\u2010studies\/penile\u2010cancer\/. Accessed August 20 2024"},{"key":"e_1_2_8_6_1","unstructured":"Department of Health.VTE risk assessment: national tool.2010. Available at:https:\/\/assets.publishing.service.gov.uk\/government\/uploads\/system\/uploads\/attachment_data\/file\/216535\/dh_134330.pdf. Accessed August 20 2024"},{"key":"e_1_2_8_7_1","unstructured":"European Association of Urology.EAU guidelines on thromboprophylaxis in urological surgery.2022. Available at:https:\/\/uroweb.org\/guidelines\/thromboprophylaxis\u2010in\u2010urological\u2010surgery. Accessed August 20 2024"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2014.02.092"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2020.11.003"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1503\/cjs.012314"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.13496"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/0284186X.2023.2206524"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2017.03.008"}],"container-title":["BJU International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bju.70378","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/bju.70378","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bju.70378","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T08:01:42Z","timestamp":1786435302000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/10.1111\/bju.70378"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,2]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1111\/bju.70378"],"URL":"https:\/\/doi.org\/10.1111\/bju.70378","archive":["Portico"],"relation":{},"ISSN":["1464-4096","1464-410X"],"issn-type":[{"value":"1464-4096","type":"print"},{"value":"1464-410X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,2]]},"assertion":[{"value":"2026-07-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}