{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T06:02:54Z","timestamp":1789365774248,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T00:00:00Z","timestamp":1789257600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T00:00:00Z","timestamp":1789257600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100023753","name":"Enhancing Diversity in Graduate Education Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100023753","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the effect of Moses\u2122 2.0 (Lumenis Be Ltd., Yokneam Illit, Israel; Boston Scientific, Marlborough, MA, USA) for lithotripsy of renal stones of 8\u201320\u2009mm in diameter on operative time, surgeon workload, and retropulsion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects\/Patients and Methods<\/jats:title>\n                    <jats:p>In our multicentre, randomised, double\u2010blind clinical trial, patients were randomised 1:1 to standard or Moses 2.0 laser lithotripsy and stratified by stone size. Patients and surgeons were blinded to laser modality. Primary outcomes were total operative time as well as surgeon workload assessed by the National Aeronautics and Space Administration\u2010Task Load Index (NASA\u2010TLX). Secondary outcomes were stone retropulsion evaluated by blinded video review and postoperative clinical outcomes. Linear regression modelling was used for analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 153 patients (79 Standard, 74 Moses 2.0) with similar clinical, stone, and operative characteristics were evaluated. There was no significant difference in operative times between the Standard and Moses 2.0 groups (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.73). Moses 2.0 was associated with lower effort, frustration, mental, physical, and temporal workload, as well as higher rated overall performance compared to the standard laser. Video review demonstrated no difference in rates of retropulsion (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.13). Complication rates (Standard: 13%; Moses 2.0: 10%) and stone\u2010free rates (Standard: 51%; Moses: 2.0 55%) were comparable.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our study evaluated the impact of Moses 2.0 technology on high\u2010powered renal stone dusting, constituting the largest double\u2010blind trial of its kind to date. There was insufficient evidence to suggest any difference in operative times or clinical outcomes when using Moses 2.0 compared to standard laser lithotripsy. Moses 2.0 was associated with reduced surgeon workload, which has implicit impact on surgeon wellness.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.70446","type":"journal-article","created":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T05:10:26Z","timestamp":1789362626000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prospective randomised double\u2010blind trial: holmium laser lithotripsy with vs without Moses\u2122 2.0"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4741-2207","authenticated-orcid":false,"given":"Kimberly A.","family":"Maciolek","sequence":"first","affiliation":[{"name":"Vanderbilt University Medical Center  Nashville TN USA"},{"name":"University of Virginia  Charlottesville VA 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California San Diego Health  San Diego CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2744-8812","authenticated-orcid":false,"given":"Ojas","family":"Shah","sequence":"additional","affiliation":[{"name":"Columbia University Irving Medical Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen L.","family":"Stern","sequence":"additional","affiliation":[{"name":"Mayo Clinic  Phoenix AZ USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger L.","family":"Sur","sequence":"additional","affiliation":[{"name":"University of California San Diego Health  San Diego CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sri","family":"Sivalingam","sequence":"additional","affiliation":[{"name":"Glickman Urological and Kidney Institute Cleveland Clinic  Cleveland OH 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