{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T23:51:57Z","timestamp":1791157917112,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T00:00:00Z","timestamp":1791072000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T00:00:00Z","timestamp":1791072000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005089","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["L258065"],"award-info":[{"award-number":["L258065"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"abstract":"\n Objectives<\/jats:title>\n Our objective was to quantify changes in the global burden of prostate, bladder, kidney and testicular cancers from 1990 to 2023 and to assess demographic contributions and characterize geographic, age\u2010specific and modelled risk\u2010attributable patterns.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n We analysed Global Burden of Disease 2023 estimates for incidence, deaths and disability\u2010adjusted life\u2010years (DALYs). Age\u2010standardised incidence rates and death rates were summarised using estimated annual percentage change. We incorporated 95% uncertainty intervals (UIs), decomposed changes in counts into population growth, population ageing and age\u2010specific rate effects, assessed 2021\u20132023 changes, and repeated country rankings after excluding locations with an implied population <1 million.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n In 2023, the four cancers accounted for approximately 2.47 million incident cases, 0.88 million deaths and 18.1 million DALYs. Prostate cancer contributed 1.41 million incident cases (95% UI 1.19\u20131.63 million) and 469\u2009000 deaths (95% UI 413\u2009000\u2013526\u2009000). From 1990 to 2023, age\u2010standardised incidence rates increased for testicular cancer (estimated annual percentage change 0.98%, 95% confidence interval [CI] 0.89\u20131.07) and kidney cancer (0.27%, 95% CI 0.13\u20130.41), was stable for prostate cancer, and decreased for bladder cancer; age\u2010standardised death rates decreased for all four cancers. Together, population growth and ageing accounted for the most increases in incident cases, whereas declining age\u2010specific rates offset deaths from prostate, bladder, kidney and testicular cancers. Small\u2010jurisdiction leaders changed materially in the population\u2010threshold sensitivity analysis. In 2023, all modelled risks accounted for 34.6% (95% UI 29.7\u201339.8) of bladder cancer DALYs and 27.1% (95% UI 17.0\u201336.7) of kidney cancer DALYs but only 1.6% (95% UI \u22125.6 to 6.8) of prostate cancer DALYs.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n The growing absolute burden of these cancers was predominantly demographic, but cancer\u2010specific and geographic trajectories differed. Testicular cancer added a young\u2010adult, rising\u2010incidence component to the conventional older\u2010age urological cancer profile. Rankings for small populations require cautious interpretation, and prevention priorities should reflect cancer\u2010specific risk patterns.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/bju.70473","type":"journal-article","created":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T23:11:56Z","timestamp":1791155516000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Global trends in urological cancers: an analysis of the global burden of disease study 2023"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-8340-549X","authenticated-orcid":false,"given":"Hanbo","family":"Lu","sequence":"first","affiliation":[{"name":"Department of Urology Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing P.R. China"},{"name":"Eight\u2010year Program of Clinical Medicine Chinese Academy of Medical Sciences, Peking Union Medical College Beijing P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusa","family":"Zhang","sequence":"additional","affiliation":[{"name":"Eight\u2010year Program of Clinical Medicine Chinese Academy of Medical Sciences, Peking Union Medical College Beijing P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Urology Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8058-9702","authenticated-orcid":false,"given":"Yushi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Urology Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing P.R. 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