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The infection cycle of SARS\u2010CoV\u20102 involves several related steps, including virus entry, gene expression, RNA replication, assembly of infectious virions and their egress. For all of these steps, the virus relies on and exploits host cell factors, cellular organelles, and processes such as endocytosis, nuclear transport, protein secretion, metabolite transport at membrane contact sites (MSC) and exocytotic pathways. To do this, SARS\u2010CoV\u20102 has evolved multifunctional viral proteins that hijack cellular factors and modulate their function by unique strategies. In this Review, we highlight cellular trafficking factors, processes, and organelles of relevance to the SARS\u2010CoV\u20102 infection cycle and how viral proteins make use of and perturb cellular transport during the viral infection cycle.<\/jats:p>","DOI":"10.1111\/boc.202200073","type":"journal-article","created":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T05:20:13Z","timestamp":1667193613000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["A snapshot of protein trafficking in SARS\u2010CoV\u20102 infection"],"prefix":"10.1111","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7450-607X","authenticated-orcid":false,"given":"Vibhu","family":"Prasad","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases Molecular Virology Heidelberg University  Heidelberg 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