{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T14:03:16Z","timestamp":1788357796220,"version":"build-2803163510"},"reference-count":46,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,6,25]],"date-time":"2023-06-25T00:00:00Z","timestamp":1687651200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain Pathology"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Autoimmune neuropathies are a heterogeneous group of rare and disabling diseases in which the immune system is thought to target antigens in the peripheral nervous system: they usually respond to immune therapies. Guillain\u2013Barr\u00e9 syndrome is divided into several subtypes including \u201cacute inflammatory demyelinating polyradiculoneuropathy,\u201d \u201cacute motor axonal neuropathy,\u201d \u201cacute motor sensory neuropathy,\u201d and other variants. Chronic forms such as chronic inflammatory demyelinating polyneuropathy (CIDP) and other subtypes and polyneuropathy associated with IgM monoclonal gammopathy; autoimmune nodopathies also belong to this group of auto\u2010immune neuropathies. It has been shown that immunoglobulin G from the serum of about 30% of CIDP patients immunolabels nodes of Ranvier or paranodes of myelinated axons. Whatever the cause of myelin damage of the peripheral nervous system, the initial attack on myelin by a dysimmune process may begin either at the internodal area or in the paranodal and nodal regions. The term \u201cnodoparanodopathy\u201d was first applied to some \u201caxonal Guillain\u2013Barr\u00e9 syndrome\u201d subtypes, then extended to cases classified as CIDP bearing IgG4 antibodies against paranodal axoglial proteins. In these cases, paranodal dissection develops in the absence of macrophage\u2010induced demyelination. In contrast, the mechanisms of demyelination of other dysimmune neuropathies induced by macrophages are unexplained, as no antibodies have been identified in such cases. The main objective of this presentation is to show that the pathology illustrates, confirms, and may explain such mechanisms.<\/jats:p>","DOI":"10.1111\/bpa.13184","type":"journal-article","created":{"date-parts":[[2023,6,25]],"date-time":"2023-06-25T20:55:25Z","timestamp":1687726525000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Pathology explains various mechanisms of auto\u2010immune inflammatory peripheral neuropathies"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0508-8403","authenticated-orcid":false,"given":"Jean\u2010Michel","family":"Vallat","sequence":"first","affiliation":[{"name":"Department and Laboratory of Neurology, National Reference Center for \u2018Rare Peripheral Neuropathies\u2019 University Hospital of Limoges (CHU Limoges)  Limoges France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0775-4625","authenticated-orcid":false,"given":"St\u00e9phane","family":"Mathis","sequence":"additional","affiliation":[{"name":"Department of Neurology (Nerve\u2010Muscle Unit), \u2018Grand Sud\u2010Ouest\u2019 National Reference Center for Neuromuscular Disorders, ALS Center University Hospital of Bordeaux (CHU Bordeaux)  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,25]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s42466-020-00064-2"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a020529"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2013.03.025"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2017-317192"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8027.2012.00372.x"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2021-326889"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000009402"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000009401"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-196905000-00001"},{"issue":"1","key":"e_1_2_12_11_1","first-page":"19","article-title":"Guillain\u2013Barr\u00e9 syndrome: an ultrastructural study of peripheral nerve in 65 patients","volume":"6","author":"Brechenmacher C","year":"1987","journal-title":"Clin Neuropathol"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880150506"},{"issue":"2","key":"e_1_2_12_13_1","first-page":"133","article-title":"Acute idiopathic polyneuritis. 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