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Considering the complications of this chronic disease, a reliable anti\u2010diabetic treatment is indispensable. An ideal oral anti\u2010diabetic drug should not only correct glucose homeostasis but also preserve or even augment beta\u2010cell function and mass, ameliorate the subclinical inflammation present under insulin\u2010resistant conditions and prevent the macro\u2010 and microvascular consequences of diabetes in order to reduce the mortality. Despite the many anti\u2010diabetic drugs already in use, there is an ongoing research for additional drugs, guided by different concepts of the pathogenesis of type 2 diabetes. This review will briefly summarize current oral anti\u2010diabetic drugs. In addition, emerging strategies for the treatment of diabetes will be described, among them the inhibition of glucagon action and anti\u2010inflammatory drugs. 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