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Although this time is generally associated with increased calmness and decreased stress responses, for a substantial subset of mothers, this period represents a time of particular risk for the onset of psychiatric disorders. Thus, post\u2010partum anxiety, depression and, to a lesser extent, psychosis may develop, and not only affect the well\u2010being of the mother but also place at risk the long\u2010term health of the infant. Although the risk factors for these disorders, as well as normal peripartum\u2010associated adaptations, are well known, the underlying aetiology of post\u2010partum psychiatric disorders remains poorly understood. However, there have been a number of attempts to model these disorders in basic research, which aim to reveal their underlying mechanisms. In the following review, we first discuss known peripartum adaptations and then describe post\u2010partum mood and anxiety disorders, including their risk factors, prevalence and symptoms. Thereafter, we discuss the animal models that have been designed in order to study them and what they have revealed about their aetiology to date. Overall, these studies show that it is feasible to study such complex disorders in animal models, but that more needs to be done in order to increase our knowledge of these severe and debilitating mood and anxiety disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Linked Articles<\/jats:title><jats:p>This article is part of a themed section on Animal Models in Psychiatry Research. To view the other articles in this section visit <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/dx.doi.org\/10.1111\/bph.2014.171.issue-20\">http:\/\/dx.doi.org\/10.1111\/bph.2014.171.issue-20<\/jats:ext-link><\/jats:p><\/jats:sec>","DOI":"10.1111\/bph.12640","type":"journal-article","created":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T11:33:57Z","timestamp":1392636837000},"page":"4539-4555","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Using animal models to study post\u2010partum psychiatric disorders"],"prefix":"10.1111","volume":"171","author":[{"given":"C V","family":"Perani","sequence":"first","affiliation":[{"name":"Department of Behavioural and Molecular Neurobiology University of Regensburg  Regensburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D A","family":"Slattery","sequence":"additional","affiliation":[{"name":"Department 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