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Out of 2,341 studies, 31 articles met inclusion criteria. Cannabigerol (range 5 to 20 mg\u00b7kg\n                    <jats:sup>\u22121<\/jats:sup>\n                    ) and cannabidivarin (range 0.2 to 400 mg\u00b7kg\n                    <jats:sup>\u22121<\/jats:sup>\n                    ) displayed efficacy in models of Huntington's disease and epilepsy. Cannabichromene (10\u201375 mg\u00b7kg\n                    <jats:sup>\u22121<\/jats:sup>\n                    ), \u0394\n                    <jats:sup>9<\/jats:sup>\n                    \u2010tetrahydrocannabinolic acid (20 mg\u00b7kg\n                    <jats:sup>\u22121<\/jats:sup>\n                    ), and tetrahydrocannabivarin (range 0.025\u20132.5 mg\u00b7kg\n                    <jats:sup>\u22121<\/jats:sup>\n                    ) showed promise in models of seizure and hypomobility, Huntington's and Parkinson's disease. Limited mechanistic data showed cannabigerol, its derivatives VCE.003 and VCE.003.2, and \u0394\n                    <jats:sup>9<\/jats:sup>\n                    \u2010tetrahydrocannabinolic acid mediated some of their effects through PPAR\u2010\u03b3, but no other receptors were probed. Further studies with these phytocannabinoids, and their combinations, are warranted across a range of neurodegenerative disorders.\n                  <\/jats:p>","DOI":"10.1111\/bph.15185","type":"journal-article","created":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T03:52:52Z","timestamp":1593575572000},"page":"4330-4352","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":110,"title":["A systematic review of minor phytocannabinoids with promising neuroprotective potential"],"prefix":"10.1111","volume":"177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7572-7429","authenticated-orcid":false,"given":"Nicole L.","family":"Stone","sequence":"first","affiliation":[{"name":"Division of Medical Sciences and Graduate Entry Medicine, School of Medicine University of Nottingham, Royal Derby Hospital  Derby UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra J.","family":"Murphy","sequence":"additional","affiliation":[{"name":"Division of Medical Sciences and Graduate Entry Medicine, School of Medicine University of Nottingham, Royal Derby Hospital  Derby UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy J.","family":"England","sequence":"additional","affiliation":[{"name":"Division of Medical Sciences and Graduate Entry Medicine, School of Medicine University of Nottingham, Royal Derby Hospital  Derby UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saoirse E.","family":"O'Sullivan","sequence":"additional","affiliation":[{"name":"Division of Medical Sciences and Graduate Entry Medicine, School of Medicine University of Nottingham, Royal Derby Hospital  Derby UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40035-019-0148-x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2004.04.001"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.14748"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.14750"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.14752"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.14749"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.214"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.9b00600"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox9010021"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.12043"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules181012663"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1155\/2008\/658520"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24152702"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000289230"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0094733"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2009.00515.x"},{"key":"e_1_2_9_18_1","volume-title":"Handbook of cannabis","author":"Cascio M. 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