{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T05:09:03Z","timestamp":1769922543696,"version":"3.49.0"},"reference-count":23,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T00:00:00Z","timestamp":1677024000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bpspubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["British J Pharmacology"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:sec><jats:title>LINKED ARTICLES<\/jats:title><jats:p>This article is part of a themed issue on Advances in Opioid Pharmacology at the Time of the Opioid Epidemic. To view the other articles in this section visit <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bph.v180.7\/issuetoc\">http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bph.v180.7\/issuetoc<\/jats:ext-link><\/jats:p><\/jats:sec>","DOI":"10.1111\/bph.16043","type":"journal-article","created":{"date-parts":[[2023,2,23]],"date-time":"2023-02-23T01:04:31Z","timestamp":1677114271000},"page":"793-796","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Opioid research in the time of the opioid crisis"],"prefix":"10.1111","volume":"180","author":[{"given":"John R.","family":"Traynor","sequence":"first","affiliation":[{"name":"Department of Pharmacology and Edward F. Domino Research Center, Department of Medicinal Chemistry University of Michigan  Ann Arbor Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose A.","family":"Moron","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Washington University Pain Center Washington University School of Medicine  St Louis Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,22]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15538"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15656"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15580"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15592"},{"key":"e_1_2_2_6_1","unstructured":"Centers for Disease Control and Prevention. (2021).Drug Overdose Deaths in the U.S. Top 100 000 Annually.https:\/\/www.cdc.gov\/nchs\/pressroom\/nchs_press_releases\/2021\/20211117.htm"},{"key":"e_1_2_2_7_1","unstructured":"Centers for Disease Control and Prevention. (2022).U.S. Overdose Deaths In 2021 Increased Half as Much as in 2020 \u2013 But Are Still Up 15%.https:\/\/www.cdc.gov\/nchs\/pressroom\/nchs_press_releases\/2022\/202205.htm"},{"key":"e_1_2_2_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15791"},{"key":"e_1_2_2_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15792"},{"key":"e_1_2_2_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15772"},{"key":"e_1_2_2_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15334"},{"key":"e_1_2_2_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15573"},{"key":"e_1_2_2_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15765"},{"key":"e_1_2_2_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15771"},{"key":"e_1_2_2_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15645"},{"key":"e_1_2_2_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1946.tb00022.x"},{"key":"e_1_2_2_17_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6643e1"},{"key":"e_1_2_2_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15730"},{"key":"e_1_2_2_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15409"},{"key":"e_1_2_2_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-019-0137-5"},{"key":"e_1_2_2_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2011.10.027"},{"key":"e_1_2_2_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15760"},{"key":"e_1_2_2_23_1","unstructured":"WHO. (2021).Opioid Overdose.https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/opioid-overdose"},{"key":"e_1_2_2_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2022.09.041"}],"container-title":["British Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bph.16043","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/bph.16043","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bph.16043","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T04:33:19Z","timestamp":1692419599000},"score":1,"resource":{"primary":{"URL":"https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/10.1111\/bph.16043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,22]]},"references-count":23,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1111\/bph.16043"],"URL":"https:\/\/doi.org\/10.1111\/bph.16043","archive":["Portico"],"relation":{},"ISSN":["0007-1188","1476-5381"],"issn-type":[{"value":"0007-1188","type":"print"},{"value":"1476-5381","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,22]]},"assertion":[{"value":"2023-02-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}