{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T01:34:28Z","timestamp":1791941668679,"version":"4.3.4"},"reference-count":0,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T00:00:00Z","timestamp":1766966400000},"content-version":"vor","delay-in-days":28,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["bpspubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["British J Pharmacology"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:p>\n                    The Concise Guide to Pharmacology 2025\/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear, accessible, and well\u2010structured, rather than the scope of the content, which spans approximately 500 pages. The Concise Guide summarises the key pharmacological properties of around 1900 human drug targets, and nearly 7000 interactions, involving around 4400 ligands. While the content is a substantially condensed version of the more detailed information and links available at the\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/www.guidetopharmacology.org\/\">www.guidetopharmacology.org<\/jats:ext-link>\n                    website, the printed guide serves as a permanent, citable, point\u2010in\u2010time record, that remains stable despite ongoing updates to the online database. The full contents of this publication can be found at\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/10.1111\/bph.70233\">https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/10.1111\/bph.70233<\/jats:ext-link>\n                    .\n                  <\/jats:p>\n                  <jats:p>The Concise Guides provide expert\u2010curated recommendations of \u2018Gold Standard\u2019 selective pharmacological tools, available either commercially or as donations, which enable the identification of individual drug targets or families of drug targets. While the Concise Guide offers a more streamlined overview, more comprehensive information, including detailed pharmacological profiles and links to multiple online databases, is available through the Guide to Pharmacology website. The 2025\/26 edition of the Concise Guide is based on material current as of mid\u20102025, and supersedes all previous editions, including the 2023\/24 Guide, and earlier Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC\u2010IUPHAR), and as such provides official IUPHAR classification and nomenclature for human drug targets, where applicable.<\/jats:p>\n                  <jats:p>Catalytic receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein\u2010coupled receptors, ion channels, nuclear hormone receptors, enzymes and transporters. Each section includes nomenclature guidance, concise summaries, information of the best available pharmacological tools, key references, and suggestions for further reading.<\/jats:p>","DOI":"10.1111\/bph.70233","type":"journal-article","created":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T02:30:36Z","timestamp":1767061836000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":83,"title":["The Concise Guide to PHARMACOLOGY 2025\/26: Catalytic receptors"],"prefix":"10.1111","volume":"182","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4417-497X","authenticated-orcid":false,"given":"Stephen P. 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