{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T09:14:25Z","timestamp":1783674865921,"version":"3.55.0"},"reference-count":106,"publisher":"Wiley","issue":"16","license":[{"start":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T00:00:00Z","timestamp":1779667200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T00:00:00Z","timestamp":1779667200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["1951"],"award-info":[{"award-number":["1951"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"publisher","award":["955879"],"award-info":[{"award-number":["955879"]}],"id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bpspubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["British J Pharmacology"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Purpose<\/jats:title>\n                    <jats:p>Autosomal dominant polycystic kidney disease (ADPKD) is a leading cause of end\u2010stage renal disease with limited treatment options. Drug repurposing offers a promising strategy to find effective treatments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Experimental Approach<\/jats:title>\n                    <jats:p>We identified birinapant, bardoxolone methyl and salicylic acid as repurposing candidates for ADPKD and applied thermal proteome profiling to identify disease\u2010relevant targets.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key Results<\/jats:title>\n                    <jats:p>\n                      Our results uncovered shared effects between the three drugs, including a thermal shift in ADP\/ATP translocases (\n                      <jats:italic>SLC25A4\/5\/6<\/jats:italic>\n                      ) caused by reduced ATP production. As expected, salicylic acid displayed a polypharmacological profile but also engaged enzymes along the N\u2010linked glycosylation pathway and inhibited\n                      <jats:italic>PTK2<\/jats:italic>\n                      (FAK), an activator of the proliferative PI3K\/Akt\/mTOR pathway. Orthogonal assays and computational modelling confirmed these findings and located the binding site (499\u2013504) of salicylic acid within\n                      <jats:italic>PTK2<\/jats:italic>\n                      's ATP\u2010binding pocket. Engagement of several targets was achieved at clinically relevant concentrations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Implications<\/jats:title>\n                    <jats:p>We have identified novel targets of three repurposing candidates that contribute to the cyst growth reducing effects in preclinical ADPKD models and identify salicylic acid, the metabolite of aspirin, as the repurposing candidate with the most promising mechanisms of action.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bph.70493","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T23:08:48Z","timestamp":1779750528000},"page":"5082-5101","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Identification of drug repurposing candidates for the treatment of polycystic kidney disease"],"prefix":"10.1111","volume":"183","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2097-6295","authenticated-orcid":false,"given":"Alina","family":"Meyer","sequence":"first","affiliation":[{"name":"Department of Pharmacy Uppsala University  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2123-1126","authenticated-orcid":false,"given":"Paraskevi","family":"Sotiropoulou","sequence":"additional","affiliation":[{"name":"Department of Biology University of Konstanz  Constance Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8574-2438","authenticated-orcid":false,"given":"Koussai","family":"Bouker","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Uppsala University  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5799-4075","authenticated-orcid":false,"given":"Dennis","family":"Svedberg","sequence":"additional","affiliation":[{"name":"Department of Chemistry Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5740-0353","authenticated-orcid":false,"given":"Rebekkah","family":"Hammar","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Uppsala University  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9750-5186","authenticated-orcid":false,"given":"Hester","family":"Bange","sequence":"additional","affiliation":[{"name":"Crown Bioscience Netherlands B. V  Leiden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8418-4956","authenticated-orcid":false,"given":"Per","family":"Larsson","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Uppsala University  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6870-0677","authenticated-orcid":false,"given":"Andr\u00e9","family":"Mateus","sequence":"additional","affiliation":[{"name":"Department of Chemistry Ume\u00e5 University  Ume\u00e5 Sweden"},{"name":"The Laboratory for Molecular Infection Medicine Sweden (MIMS), Ume\u00e5  Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0416-3811","authenticated-orcid":false,"given":"Daniel R.","family":"Dietrich","sequence":"additional","affiliation":[{"name":"Department of Biology University of Konstanz  Constance Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3708-7395","authenticated-orcid":false,"given":"Per","family":"Artursson","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Uppsala University  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,25]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-024-07487-w"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.70234"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.70233"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.70235"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.14112"},{"key":"e_1_2_13_7_1","first-page":"231","article-title":"Salsalate, an Old, Inexpensive Drug with Potential New Indications: A Review of the Evidence from 3 Recent Studies","volume":"7","author":"Anderson K.","year":"2014","journal-title":"American Health & Drug Benefits"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2014.12.003"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2014.10.005"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2014.05.007"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2020.03.023"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2019.03.013"},{"key":"e_1_2_13_13_1","doi-asserted-by":"crossref","unstructured":"Batth T. S. van derRijst S. van deKooij B. vanKempen L. J. deGraaf E. L. Lijnzaad P. Altelaar M. &Olsen J. V.(2024).Streamlined Proteome\u2010Wide Identification of Drug Targets Indicates Organ\u2010Specific Engagement. 2024.02.08.578880. doi:https:\/\/doi.org\/10.1101\/2024.02.08.578880","DOI":"10.1101\/2024.02.08.578880"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.03.053"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-13-0798"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/2472555217716056"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.2A1013-568RRR"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12030731"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32782-X"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2017050483"},{"key":"e_1_2_13_21_1","unstructured":"Corso G. St\u00e4rk H. Jing B. Barzilay R.&Jaakkola T.(2023).DiffDock: Diffusion Steps Twists and Turns for Molecular Docking.https:\/\/doi.org\/10.48550\/arXiv.2210.01776"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.17441"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2010.32"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1306033"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells12020219"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41581-021-00411-9"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2013020176"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/oncsis.2017.65"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1124\/pr.119.018762"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-06149-4"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2020.109648"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42255-020-0191-z"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-45539-8"},{"key":"e_1_2_13_34_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-20-0812"},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-022-04430-y"},{"key":"e_1_2_13_36_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1215327"},{"key":"e_1_2_13_37_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2020111560"},{"key":"e_1_2_13_38_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI64313"},{"key":"e_1_2_13_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41596-018-0082-x"},{"key":"e_1_2_13_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40495-016-0050-5"},{"key":"e_1_2_13_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-020-0801-4"},{"key":"e_1_2_13_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2023.108278"},{"key":"e_1_2_13_43_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.102.037580"},{"key":"e_1_2_13_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2008.02.002"},{"key":"e_1_2_13_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2020.102628"},{"key":"e_1_2_13_46_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2016.00206"},{"key":"e_1_2_13_47_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2018.09.016"},{"key":"e_1_2_13_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-19529-8"},{"key":"e_1_2_13_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2019.08.041"},{"key":"e_1_2_13_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2024.116913"},{"key":"e_1_2_13_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-023-06226-9"},{"key":"e_1_2_13_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-45461-2"},{"key":"e_1_2_13_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2019.11.046"},{"key":"e_1_2_13_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2019.109468"},{"key":"e_1_2_13_55_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1701848114"},{"key":"e_1_2_13_56_1","doi-asserted-by":"publisher","DOI":"10.15252\/msb.20199232"},{"key":"e_1_2_13_57_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pharmtox-052120-013205"},{"key":"e_1_2_13_58_1","doi-asserted-by":"publisher","DOI":"10.1021\/mp4000822"},{"key":"e_1_2_13_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep43047"},{"key":"e_1_2_13_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03106-1"},{"key":"e_1_2_13_61_1","doi-asserted-by":"publisher","DOI":"10.1111\/cts.70214"},{"key":"e_1_2_13_62_1","doi-asserted-by":"publisher","DOI":"10.1088\/1758-5090\/ae3eb9"},{"key":"e_1_2_13_63_1","doi-asserted-by":"publisher","DOI":"10.1124\/mol.51.6.907"},{"key":"e_1_2_13_64_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1233606"},{"key":"e_1_2_13_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2005.02.009"},{"key":"e_1_2_13_66_1","doi-asserted-by":"crossref","unstructured":"Noberini R. &Bonaldi T.(2023).Proteomics contributions to epigenetic drug discovery. PROTEOMICS n\/a 2200435.","DOI":"10.1002\/pmic.202200435"},{"key":"e_1_2_13_67_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29783"},{"key":"e_1_2_13_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0969-2126(02)00907-3"},{"key":"e_1_2_13_69_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26144250"},{"key":"e_1_2_13_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exppara.2023.108618"},{"key":"e_1_2_13_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2023.112085"},{"key":"e_1_2_13_72_1","doi-asserted-by":"publisher","DOI":"10.1159\/000327599"},{"key":"e_1_2_13_73_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1105351"},{"key":"e_1_2_13_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2022.109959"},{"key":"e_1_2_13_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2019.109495"},{"key":"e_1_2_13_76_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2018.168"},{"key":"e_1_2_13_77_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu14214651"},{"key":"e_1_2_13_78_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0036325"},{"key":"e_1_2_13_79_1","doi-asserted-by":"publisher","DOI":"10.1080\/10715762.2017.1295452"},{"key":"e_1_2_13_80_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0087660"},{"key":"e_1_2_13_81_1","doi-asserted-by":"crossref","unstructured":"Rivera\u2010Mej\u00edas P. Le Sueur C. Kurzawa N. Becher I.&Savitski M. M.(2024).Subcellular thermal profiling enables the deep functional exploration of the mitochondrial proteome. (Molecular Biology 2024).https:\/\/doi.org\/10.1101\/2024.02.27.582308","DOI":"10.1101\/2024.02.27.582308"},{"key":"e_1_2_13_82_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1255784"},{"key":"e_1_2_13_83_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-018-0273-y"},{"key":"e_1_2_13_84_1","doi-asserted-by":"publisher","DOI":"10.14573\/altex.1710181"},{"key":"e_1_2_13_85_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-019-02469-8"},{"key":"e_1_2_13_86_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00280-016-3010-1"},{"key":"e_1_2_13_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2020.109644"},{"key":"e_1_2_13_88_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1011632"},{"key":"e_1_2_13_89_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac1000"},{"key":"e_1_2_13_90_1","doi-asserted-by":"crossref","unstructured":"Team C. D.Boitreaud J. Dent J. McPartlon M. Meier J. Reis V. Rogozhnikov A. &Wu K.(2024).Chai\u20101: Decoding the molecular interactions of life. 2024.10.10.615955.https:\/\/doi.org\/10.1101\/2024.10.10.615955","DOI":"10.1101\/2024.10.10.615955"},{"key":"e_1_2_13_91_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac1052"},{"key":"e_1_2_13_92_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1205511"},{"key":"e_1_2_13_93_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.molpharmaceut.8b00064"},{"key":"e_1_2_13_94_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2016.136"},{"key":"e_1_2_13_95_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22010430"},{"key":"e_1_2_13_96_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddh336"},{"key":"e_1_2_13_97_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1160809"},{"key":"e_1_2_13_98_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bty816"},{"key":"e_1_2_13_99_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.37.1.148"},{"key":"e_1_2_13_100_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.90405.2008"},{"key":"e_1_2_13_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2014.05.013"},{"key":"e_1_2_13_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2014.10.006"},{"key":"e_1_2_13_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2012.11.022"},{"key":"e_1_2_13_104_1","doi-asserted-by":"crossref","unstructured":"Wohlwend J. CorsoG. PassaroS. GetzN. ReveizM. LeidalK. SwiderskiW. AtkinsonL. PortnoiT. ChinnI. SilterraJ. JaakkolaT. &BarzilayR.(2024).Boltz\u20101: Democratizing Biomolecular Interaction Modeling. 2024.11.19.624167. doi:https:\/\/doi.org\/10.1101\/2024.11.19.624167","DOI":"10.1101\/2024.11.19.624167"},{"key":"e_1_2_13_105_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1819728116"},{"key":"e_1_2_13_106_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.578315"},{"key":"e_1_2_13_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2023.02.010"}],"container-title":["British Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bph.70493","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/bph.70493","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bph.70493","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T08:25:38Z","timestamp":1783671938000},"score":1,"resource":{"primary":{"URL":"https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/10.1111\/bph.70493"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,25]]},"references-count":106,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1111\/bph.70493"],"URL":"https:\/\/doi.org\/10.1111\/bph.70493","archive":["Portico"],"relation":{},"ISSN":["0007-1188","1476-5381"],"issn-type":[{"value":"0007-1188","type":"print"},{"value":"1476-5381","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,25]]},"assertion":[{"value":"2025-08-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}