{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T04:42:51Z","timestamp":1792471371080,"version":"4.5.0"},"reference-count":478,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,1,22]],"date-time":"2020-01-22T00:00:00Z","timestamp":1579651200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001348","name":"Agency for Science, Technology and Research","doi-asserted-by":"publisher","award":["A*STAR Research Attachment Programme (ARAP)"],"award-info":[{"award-number":["A*STAR Research Attachment Programme (ARAP)"]}],"id":[{"id":"10.13039\/501100001348","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001348","name":"Agency for Science, Technology and Research","doi-asserted-by":"publisher","award":["IAF\u2010PP H17\/01\/a0\/004"],"award-info":[{"award-number":["IAF\u2010PP H17\/01\/a0\/004"]}],"id":[{"id":"10.13039\/501100001348","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001348","name":"Agency for Science, Technology and Research","doi-asserted-by":"publisher","award":["IAF\u2010PP H17\/01\/a0\/008"],"award-info":[{"award-number":["IAF\u2010PP H17\/01\/a0\/008"]}],"id":[{"id":"10.13039\/501100001348","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014653","name":"Manchester Biomedical Research Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014653","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000770","name":"University of Manchester","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000770","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006686","name":"University of Miami","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006686","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Biological Reviews"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>The nervous system communicates with peripheral tissues through nerve fibres and the systemic release of hypothalamic and pituitary neurohormones. Communication between the nervous system and the largest human organ, skin, has traditionally received little attention. In particular, the neuro\u2010regulation of sebaceous glands (SGs), a major skin appendage, is rarely considered. Yet, it is clear that the SG is under stringent pituitary control, and forms a fascinating, clinically relevant peripheral target organ in which to study the neuroendocrine and neural regulation of epithelia. Sebum, the major secretory product of the SG, is composed of a complex mixture of lipids resulting from the holocrine secretion of specialised epithelial cells (sebocytes). It is indicative of a role of the neuroendocrine system in SG function that excess circulating levels of growth hormone, thyroxine or prolactin result in increased sebum production (seborrhoea). Conversely, growth hormone deficiency, hypothyroidism, and adrenal insufficiency result in reduced sebum production and dry skin. Furthermore, the androgen sensitivity of SGs appears to be under neuroendocrine control, as hypophysectomy (removal of the pituitary) renders SGs largely insensitive to stimulation by testosterone, which is crucial for maintaining SG homeostasis. However, several neurohormones, such as adrenocorticotropic hormone and \u03b1\u2010melanocyte\u2010stimulating hormone, can stimulate sebum production independently of either the testes or the adrenal glands, further underscoring the importance of neuroendocrine control in SG biology. Moreover, sebocytes synthesise several neurohormones and express their receptors, suggestive of the presence of neuro\u2010autocrine mechanisms of sebocyte modulation. Aside from the neuroendocrine system, it is conceivable that secretion of neuropeptides and neurotransmitters from cutaneous nerve endings may also act on sebocytes or their progenitors, given that the skin is richly innervated. However, to date, the neural controls of SG development and function remain poorly investigated and incompletely understood. Botulinum toxin\u2010mediated or facial paresis\u2010associated reduction of human sebum secretion suggests that cutaneous nerve\u2010derived substances modulate lipid and inflammatory cytokine synthesis by sebocytes, possibly implicating the nervous system in acne pathogenesis. Additionally, evidence suggests that cutaneous denervation in mice alters the expression of key regulators of SG homeostasis. In this review, we examine the current evidence regarding neuroendocrine and neurobiological regulation of human SG function in physiology and pathology. We further call attention to this line of research as an instructive model for probing and therapeutically manipulating the mechanistic links between the nervous system and mammalian skin.<\/jats:p>","DOI":"10.1111\/brv.12579","type":"journal-article","created":{"date-parts":[[2020,1,23]],"date-time":"2020-01-23T06:26:47Z","timestamp":1579760807000},"page":"592-624","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":91,"title":["Neuroendocrinology and neurobiology of sebaceous glands"],"prefix":"10.1111","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8456-7394","authenticated-orcid":false,"given":"Richard W.","family":"Clayton","sequence":"first","affiliation":[{"name":"Centre for Dermatology, School of Biological Sciences University of Manchester, and NIHR Manchester Biomedical Research Centre  Stopford Building, Oxford Road Manchester M13 9PT U.K."},{"name":"Skin Research Institute of Singapore Agency for Science, Technology and Research  11 Mandalay Road, #17\u201001 Clinical Sciences Building 308232 Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewan A.","family":"Langan","sequence":"additional","affiliation":[{"name":"Centre for Dermatology, School of Biological Sciences University of Manchester, and NIHR Manchester Biomedical Research Centre  Stopford Building, Oxford Road Manchester M13 9PT U.K."},{"name":"Department of Dermatology, Allergology und Venereology University of L\u00fcbeck  Ratzeburger Allee 160, L\u00fcbeck 23538 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M.","family":"Ansell","sequence":"additional","affiliation":[{"name":"Centre for Dermatology, School of Biological Sciences University of Manchester, and NIHR Manchester Biomedical Research Centre  Stopford Building, Oxford Road Manchester M13 9PT U.K."},{"name":"Division of Cell Matrix Biology and Regenerative Medicine University of Manchester  Michael Smith Building, Oxford Road, Manchester M13 9PT U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivo J. H. M.","family":"de Vos","sequence":"additional","affiliation":[{"name":"Skin Research Institute of Singapore Agency for Science, Technology and Research  11 Mandalay Road, #17\u201001 Clinical Sciences Building 308232 Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"G\u00f6bel","sequence":"additional","affiliation":[{"name":"Skin Research Institute of Singapore Agency for Science, Technology and Research  11 Mandalay Road, #17\u201001 Clinical Sciences Building 308232 Singapore"},{"name":"Department of Dermatology, Cologne Excellence Cluster on Stress Responses in Aging Associated Diseases (CECAD), and Centre for Molecular Medicine Cologne The University of Cologne  Joseph\u2010Stelzmann\u2010Stra\u00dfe 26, Cologne 50931 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlon R.","family":"Schneider","sequence":"additional","affiliation":[{"name":"German Federal Institute for Risk Assessment (BfR) German Centre for the Protection of Laboratory Animals (Bf3R), Max\u2010Dohrn\u2010Stra\u00dfe 8\u201310  Berlin 10589 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Picardo","sequence":"additional","affiliation":[{"name":"Cutaneous Physiopathology and Integrated Centre of Metabolomics Research San Gallicano Dermatological Institute IRCCS  Via Elio Chianesi 53, Rome 00144 Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinhong","family":"Lim","sequence":"additional","affiliation":[{"name":"Lee Kong Chian School of Medicine Nanyang Technological University  50 Nanyang Avenue 639798 Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurice A. M.","family":"van Steensel","sequence":"additional","affiliation":[{"name":"Skin Research Institute of Singapore Agency for Science, Technology and Research  11 Mandalay Road, #17\u201001 Clinical Sciences Building 308232 Singapore"},{"name":"Lee Kong Chian School of Medicine Nanyang Technological University  50 Nanyang Avenue 639798 Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Paus","sequence":"additional","affiliation":[{"name":"Centre for Dermatology, School of Biological Sciences University of Manchester, and NIHR Manchester Biomedical Research Centre  Stopford Building, Oxford Road Manchester M13 9PT U.K."},{"name":"Dr. Phllip Frost Department of Dermatology and Cutaneous Surgery University of Miami Miller School of Medicine  1600 NW 10th Avenue, RMSB 2023A, Miami FL 33136 U.S.A."},{"name":"Monasterium Laboratory Mendelstra\u00dfe 17, M\u00fcnster  48149 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,1,22]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2006.00561.x"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.09.060"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06763.x"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2006.00443.x"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13787"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01664010"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1043-2760(98)00079-4"},{"key":"e_1_2_13_9_1","first-page":"179","article-title":"Immunohistochemical localization of thyroid hormone nuclear receptors in human hair follicles and in vitro effect of L\u2010triiodothyronine on cultured cells of hair follicles and skin","volume":"44","author":"Ahsan M. K.","year":"1998","journal-title":"The Journal of Medical Investigation"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1995.tb03381.x"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12616181"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12699"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000051828"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)63574-2"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01952293"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000145417"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700104"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06847.x"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0189539"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12544621"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.79.5.1444"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1981.tb08169.x"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2010.03896.x"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/cpr.12524"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.med.53.082901.104018"},{"issue":"110","key":"e_1_2_13_26_1","first-page":"e53855","article-title":"Optical monitoring of living nerve terminal labeling in hair follicle lanceolate endings of the ex vivo mouse ear skin","author":"Bewick G. S.","year":"2016","journal-title":"Journal of Visualized Experiments"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.227"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-015-0147-3"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1983.01650300027010"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1976.tb00913.x"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tea.2013.0535"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1931.tb09468.x"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-016-1103-3"},{"key":"e_1_2_13_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2008.361"},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0022-202x.2001.01704.x"},{"key":"e_1_2_13_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-2744(199801)21:1<2::AID-MC2>3.0.CO;2-R"},{"key":"e_1_2_13_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ghir.2012.02.006"},{"key":"e_1_2_13_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2006.01898.x"},{"key":"e_1_2_13_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(03)46031-7"},{"key":"e_1_2_13_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19970929)386:3<379::AID-CNE4>3.0.CO;2-Z"},{"key":"e_1_2_13_41_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.1999.00791.x"},{"key":"e_1_2_13_42_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.118620"},{"key":"e_1_2_13_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4800(65)90001-8"},{"key":"e_1_2_13_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2011.02.021"},{"key":"e_1_2_13_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1973.tb07545.x"},{"key":"e_1_2_13_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1973.tb15453.x"},{"key":"e_1_2_13_47_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5712.769"},{"key":"e_1_2_13_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1971.tb06856.x"},{"key":"e_1_2_13_49_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5948.19"},{"key":"e_1_2_13_50_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5797.406"},{"key":"e_1_2_13_51_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.286.6372.1169"},{"key":"e_1_2_13_52_1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.2340\/0001555551113","article-title":"The sebotrophic effect of pregnancy","volume":"55","author":"Burton J. L.","year":"1975","journal-title":"Acta Dermato\u2010Venereologica"},{"key":"e_1_2_13_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2017.06.020"},{"key":"e_1_2_13_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12507"},{"key":"e_1_2_13_55_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.D008391"},{"key":"e_1_2_13_56_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M067942"},{"key":"e_1_2_13_57_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.141.3.333"},{"key":"e_1_2_13_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1972.tb01892.x"},{"key":"e_1_2_13_59_1","doi-asserted-by":"publisher","DOI":"10.1021\/cn5000919"},{"key":"e_1_2_13_60_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.287.6402.1346-a"},{"key":"e_1_2_13_61_1","doi-asserted-by":"publisher","DOI":"10.1159\/000140174"},{"key":"e_1_2_13_62_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.137.5.1752"},{"key":"e_1_2_13_63_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI0213880"},{"key":"e_1_2_13_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80467-5"},{"key":"e_1_2_13_65_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.38883"},{"key":"e_1_2_13_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2014.02.001"},{"key":"e_1_2_13_67_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.7.897"},{"key":"e_1_2_13_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13855"},{"key":"e_1_2_13_69_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1550265"},{"key":"e_1_2_13_70_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2011.212"},{"key":"e_1_2_13_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.17981"},{"key":"e_1_2_13_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2008.08.034"},{"key":"e_1_2_13_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(71)91782-X"},{"key":"e_1_2_13_74_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1972.tb07419.x"},{"key":"e_1_2_13_75_1","first-page":"1","article-title":"Severity of acne and sebum excretion rate","volume":"1","author":"Cotterill J. A.","year":"1971","journal-title":"British Journal of Dermatology"},{"key":"e_1_2_13_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2013.01.013"},{"key":"e_1_2_13_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtos.2014.01.005"},{"key":"e_1_2_13_78_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.161191698"},{"key":"e_1_2_13_79_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.142.6.8179"},{"key":"e_1_2_13_80_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1970.tb15740.x"},{"key":"e_1_2_13_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2013.05.016"},{"key":"e_1_2_13_82_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.132753"},{"key":"e_1_2_13_83_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12219"},{"key":"e_1_2_13_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2014.12.004"},{"key":"e_1_2_13_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2015.11.013"},{"key":"e_1_2_13_86_1","first-page":"145","article-title":"Keratinocyte growth factor is an important endogenous mediator of hair follicle growth, development, and differentiation. Normalization of the nu\/nu follicular differentiation defect and amelioration of chemotherapy\u2010induced alopecia","volume":"147","author":"Danilenko D. M.","year":"1995","journal-title":"American Journal of Pathology"},{"key":"e_1_2_13_87_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00737-018-0899-x"},{"key":"e_1_2_13_88_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1026725122142"},{"key":"e_1_2_13_89_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.140.9.6957"},{"key":"e_1_2_13_90_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-015-0374-6"},{"key":"e_1_2_13_91_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.07-104877"},{"key":"e_1_2_13_92_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0007579"},{"key":"e_1_2_13_93_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1969.157"},{"key":"e_1_2_13_94_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.R700016-JLR200"},{"key":"e_1_2_13_95_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14374"},{"key":"e_1_2_13_96_1","first-page":"9","article-title":"Ultrastructural observation of possible nerve endings in rat sebaceous gland","volume":"150","author":"Dugan K. H.","year":"1974","journal-title":"Cell and Tissue Research"},{"key":"e_1_2_13_97_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0150297"},{"key":"e_1_2_13_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-595X(86)80028-7"},{"key":"e_1_2_13_99_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0510181"},{"key":"e_1_2_13_100_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12724451"},{"key":"e_1_2_13_101_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1975.tb03083.x"},{"key":"e_1_2_13_102_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0660407"},{"key":"e_1_2_13_103_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0450245"},{"key":"e_1_2_13_104_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0450257"},{"key":"e_1_2_13_105_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0480083"},{"key":"e_1_2_13_106_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0480073"},{"key":"e_1_2_13_107_1","volume-title":"Rook's Textbook of Dermatology","author":"Eedy D.","year":"2016"},{"key":"e_1_2_13_108_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-016-2312-0"},{"key":"e_1_2_13_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2011.04.001"},{"key":"e_1_2_13_110_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.023960"},{"key":"e_1_2_13_111_1","doi-asserted-by":"publisher","DOI":"10.1089\/rej.2011.1294"},{"key":"e_1_2_13_112_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2010.04752.x"},{"key":"e_1_2_13_113_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2006.1861"},{"key":"e_1_2_13_114_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1966.67"},{"key":"e_1_2_13_115_1","doi-asserted-by":"publisher","DOI":"10.1111\/ics.12442"},{"key":"e_1_2_13_116_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M808915200"},{"key":"e_1_2_13_117_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00418-011-0798-y"},{"key":"e_1_2_13_118_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-017-0971-2"},{"key":"e_1_2_13_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(98)01067-9"},{"key":"e_1_2_13_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2015.03.005"},{"key":"e_1_2_13_121_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2016.10.017"},{"key":"e_1_2_13_122_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269216307087148"},{"key":"e_1_2_13_123_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.21"},{"key":"e_1_2_13_124_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2003.12134.x"},{"key":"e_1_2_13_125_1","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2006.050468"},{"key":"e_1_2_13_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)64295-2"},{"key":"e_1_2_13_127_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2008.348"},{"key":"e_1_2_13_128_1","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfx179"},{"key":"e_1_2_13_129_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2011.12.028"},{"key":"e_1_2_13_130_1","doi-asserted-by":"publisher","DOI":"10.1159\/000116245"},{"key":"e_1_2_13_131_1","doi-asserted-by":"publisher","DOI":"10.2174\/156800705774933069"},{"key":"e_1_2_13_132_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02505281"},{"key":"e_1_2_13_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2015.09.013"},{"key":"e_1_2_13_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4165(97)00046-9"},{"key":"e_1_2_13_135_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08959.x"},{"key":"e_1_2_13_136_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00434.2002"},{"key":"e_1_2_13_137_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(05)70378-8"},{"key":"e_1_2_13_138_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.08-126417"},{"key":"e_1_2_13_139_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81631-1"},{"key":"e_1_2_13_140_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1006890212478"},{"key":"e_1_2_13_141_1","doi-asserted-by":"publisher","DOI":"10.1002\/bies.10056"},{"key":"e_1_2_13_142_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0037137"},{"key":"e_1_2_13_143_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2016.03.018"},{"key":"e_1_2_13_144_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12680076"},{"key":"e_1_2_13_145_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1973.tb01911.x"},{"key":"e_1_2_13_146_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6007.432"},{"key":"e_1_2_13_147_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2013.02.012"},{"key":"e_1_2_13_148_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2011.01631.x"},{"key":"e_1_2_13_149_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12280318"},{"key":"e_1_2_13_150_1","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2008.071089"},{"key":"e_1_2_13_151_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2010.01192.x"},{"key":"e_1_2_13_152_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2012.10.013"},{"key":"e_1_2_13_153_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R114.619957"},{"key":"e_1_2_13_154_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12343608"},{"key":"e_1_2_13_155_1","first-page":"389","article-title":"Cell kinetics in the sebaceous glands of the mouse. I. The glands in resting skin","volume":"7","author":"Hamilton E.","year":"1974","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_13_156_1","first-page":"399","article-title":"Cell kinetics in the sebaceous glands of the mouse. II. The glands during hair growth","volume":"7","author":"Hamilton E.","year":"1974","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_13_157_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-1-7-570"},{"key":"e_1_2_13_158_1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-112-28050"},{"key":"e_1_2_13_159_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2018.02.009"},{"key":"e_1_2_13_160_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.184.4.1385"},{"key":"e_1_2_13_161_1","first-page":"195","article-title":"Role of mast cells and sensory nerves in skin inflammation","volume":"145","author":"Harvima I. T.","year":"2010","journal-title":"Giornale Italiano di Dermatologia e Venereologia"},{"key":"e_1_2_13_162_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1963.5"},{"key":"e_1_2_13_163_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1953.24"},{"key":"e_1_2_13_164_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1955.sp005370"},{"key":"e_1_2_13_165_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2000.03249.x"},{"key":"e_1_2_13_166_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12207"},{"key":"e_1_2_13_167_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12344044"},{"key":"e_1_2_13_168_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2010.01125.x"},{"key":"e_1_2_13_169_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-540-46911-7_5"},{"key":"e_1_2_13_170_1","doi-asserted-by":"publisher","DOI":"10.1530\/JME-13-0220"},{"key":"e_1_2_13_171_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.06.048"},{"key":"e_1_2_13_172_1","doi-asserted-by":"publisher","DOI":"10.1111\/joim.12850"},{"key":"e_1_2_13_173_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0009837"},{"key":"e_1_2_13_174_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.140R001"},{"key":"e_1_2_13_175_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1953.84"},{"key":"e_1_2_13_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2015.11.027"},{"key":"e_1_2_13_177_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jidsymp.5650007"},{"key":"e_1_2_13_178_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1959.7"},{"key":"e_1_2_13_179_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.202"},{"key":"e_1_2_13_180_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.76.2.524"},{"key":"e_1_2_13_181_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.04-1968fje"},{"key":"e_1_2_13_182_1","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200304050-00003"},{"key":"e_1_2_13_183_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2015.148"},{"key":"e_1_2_13_184_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1473-2165.2006.00250.x"},{"key":"e_1_2_13_185_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2009.04.014"},{"key":"e_1_2_13_186_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtos.2016.08.001"},{"key":"e_1_2_13_187_1","first-page":"2549","article-title":"Correlations of SOX9 expression with serum IGF1 and inflammatory cytokines IL\u20101\u03b1 and IL\u20106 in skin lesions of patients with acne","volume":"22","author":"Ji J.","year":"2018","journal-title":"European Review for Medical and Pharmacological Sciences"},{"key":"e_1_2_13_188_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2015.56"},{"key":"e_1_2_13_189_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40001-016-0212-2"},{"key":"e_1_2_13_190_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2014.00472"},{"key":"e_1_2_13_191_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2014.293"},{"key":"e_1_2_13_192_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2013.06.037"},{"key":"e_1_2_13_193_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.11-8113"},{"key":"e_1_2_13_194_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-016-9378-8"},{"key":"e_1_2_13_195_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-09-0923"},{"key":"e_1_2_13_196_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1013"},{"key":"e_1_2_13_197_1","doi-asserted-by":"publisher","DOI":"10.1159\/000375370"},{"key":"e_1_2_13_198_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2008.369"},{"key":"e_1_2_13_199_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1203778"},{"key":"e_1_2_13_200_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2006.00004.x"},{"key":"e_1_2_13_201_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.12543"},{"key":"e_1_2_13_202_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1959.156"},{"key":"e_1_2_13_203_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12676801"},{"key":"e_1_2_13_204_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1958.23"},{"key":"e_1_2_13_205_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1956.71"},{"key":"e_1_2_13_206_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.12.031"},{"key":"e_1_2_13_207_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12682040"},{"key":"e_1_2_13_208_1","doi-asserted-by":"publisher","DOI":"10.1262\/jrd.49.465"},{"key":"e_1_2_13_209_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.01-0254fje"},{"key":"e_1_2_13_210_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2016.10.010"},{"key":"e_1_2_13_211_1","doi-asserted-by":"publisher","DOI":"10.5114\/pjp.2018.75336"},{"key":"e_1_2_13_212_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-961811"},{"key":"e_1_2_13_213_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2014.08.007"},{"key":"e_1_2_13_214_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2015.12.041"},{"key":"e_1_2_13_215_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0022-202X.2004.23425.x"},{"key":"e_1_2_13_216_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-961816"},{"key":"e_1_2_13_217_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11102-007-0028-8"},{"key":"e_1_2_13_218_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1346"},{"key":"e_1_2_13_219_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000000152"},{"key":"e_1_2_13_220_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-017-1508-x"},{"key":"e_1_2_13_221_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13545"},{"key":"e_1_2_13_222_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12836"},{"key":"e_1_2_13_223_1","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1450147"},{"key":"e_1_2_13_224_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1955.69"},{"key":"e_1_2_13_225_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1954.6"},{"key":"e_1_2_13_226_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1986.tb00458.x"},{"key":"e_1_2_13_227_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2011.01421.x"},{"key":"e_1_2_13_228_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2009.106"},{"key":"e_1_2_13_229_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-008-0854-1"},{"key":"e_1_2_13_230_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminoncol.2016.02.022"},{"key":"e_1_2_13_231_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12066"},{"key":"e_1_2_13_232_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2013.06.009"},{"key":"e_1_2_13_233_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.01901"},{"key":"e_1_2_13_234_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12886"},{"key":"e_1_2_13_235_1","doi-asserted-by":"publisher","DOI":"10.1159\/000445942"},{"key":"e_1_2_13_236_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12340"},{"key":"e_1_2_13_237_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2903"},{"key":"e_1_2_13_238_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1601599113"},{"key":"e_1_2_13_239_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.01052"},{"key":"e_1_2_13_240_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1260467"},{"key":"e_1_2_13_241_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-29742-7"},{"key":"e_1_2_13_242_1","doi-asserted-by":"publisher","DOI":"10.2147\/AHMT.S55832"},{"key":"e_1_2_13_243_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00414-011-0567-4"},{"key":"e_1_2_13_244_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2015.02.008"},{"key":"e_1_2_13_245_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2008.07.005"},{"key":"e_1_2_13_246_1","doi-asserted-by":"publisher","DOI":"10.1159\/000231524"},{"key":"e_1_2_13_247_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12260695"},{"key":"e_1_2_13_248_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01294730"},{"key":"e_1_2_13_249_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004030050354"},{"key":"e_1_2_13_250_1","doi-asserted-by":"publisher","DOI":"10.1177\/002215540004800703"},{"key":"e_1_2_13_251_1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.51.594.231"},{"key":"e_1_2_13_252_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.891401"},{"key":"e_1_2_13_253_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091860105"},{"key":"e_1_2_13_254_1","first-page":"101","article-title":"Untersuchungen \u00fcber die Funktion der Talgdrusen","volume":"1","author":"Miescher G.","year":"1944","journal-title":"Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften"},{"key":"e_1_2_13_255_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0099173"},{"key":"e_1_2_13_256_1","doi-asserted-by":"publisher","DOI":"10.1053\/meta.2002.33184"},{"key":"e_1_2_13_257_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1986.tb04880.x"},{"key":"e_1_2_13_258_1","doi-asserted-by":"publisher","DOI":"10.1093\/asj\/sju150"},{"key":"e_1_2_13_259_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2015.08.001"},{"key":"e_1_2_13_260_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2013.2189"},{"key":"e_1_2_13_261_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0151-9638(07)92826-4"},{"key":"e_1_2_13_262_1","first-page":"145","article-title":"Histology and cytochemistry of human skin XII cholinesterases in the hair follicles of the scalp","volume":"37","author":"Montagna W.","year":"1957","journal-title":"Journal of Investigative Dermatology"},{"key":"e_1_2_13_263_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-505263-4.50017-0"},{"key":"e_1_2_13_264_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-505263-4.50012-1"},{"key":"e_1_2_13_265_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-505263-4.50015-7"},{"key":"e_1_2_13_266_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.17083"},{"key":"e_1_2_13_267_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1983.tb07080.x"},{"key":"e_1_2_13_268_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2003.12233.x"},{"key":"e_1_2_13_269_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2009.384"},{"key":"e_1_2_13_270_1","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.55.7.603"},{"key":"e_1_2_13_271_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1984.tb06635.x"},{"key":"e_1_2_13_272_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.186.4158.19"},{"key":"e_1_2_13_273_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12259307"},{"key":"e_1_2_13_274_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.129.1.95"},{"key":"e_1_2_13_275_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-3427"},{"key":"e_1_2_13_276_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1834202100"},{"key":"e_1_2_13_277_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0480373"},{"key":"e_1_2_13_278_1","doi-asserted-by":"publisher","DOI":"10.1111\/ane.12334"},{"key":"e_1_2_13_279_1","first-page":"129","article-title":"Hyperprolactinemia and 5\u2010alpha\u2010reductase activity","volume":"17","author":"Noci I.","year":"1986","journal-title":"Acta Europaea Fertilitatis"},{"key":"e_1_2_13_280_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2008.05.009"},{"key":"e_1_2_13_281_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.75.5.1368"},{"key":"e_1_2_13_282_1","doi-asserted-by":"publisher","DOI":"10.2131\/jts.9.151"},{"key":"e_1_2_13_283_1","doi-asserted-by":"publisher","DOI":"10.1159\/000439378"},{"key":"e_1_2_13_284_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13042"},{"key":"e_1_2_13_285_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI64628"},{"key":"e_1_2_13_286_1","doi-asserted-by":"publisher","DOI":"10.3171\/2016.8.JNS161123"},{"key":"e_1_2_13_287_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2014.02.015"},{"key":"e_1_2_13_288_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0012-1606(02)00042-8"},{"key":"e_1_2_13_289_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.11.058"},{"key":"e_1_2_13_290_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-90-4-903"},{"key":"e_1_2_13_291_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2013.07.010"},{"key":"e_1_2_13_292_1","doi-asserted-by":"publisher","DOI":"10.1097\/MJT.0000000000000390"},{"key":"e_1_2_13_293_1","doi-asserted-by":"publisher","DOI":"10.4161\/derm.1.3.8473"},{"key":"e_1_2_13_294_1","doi-asserted-by":"publisher","DOI":"10.1080\/10715760290021342"},{"key":"e_1_2_13_295_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1987.tb07353.x"},{"key":"e_1_2_13_296_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00187.2013"},{"key":"e_1_2_13_297_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.retram.2016.10.003"},{"key":"e_1_2_13_298_1","volume-title":"Rook's Textbook of Dermatology","author":"Paus R.","year":"2016"},{"key":"e_1_2_13_299_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2014.06.002"},{"key":"e_1_2_13_300_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.1999.00740.x"},{"key":"e_1_2_13_301_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2005.10.002"},{"key":"e_1_2_13_302_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1967.tb11392.x"},{"key":"e_1_2_13_303_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2001.01232.x"},{"key":"e_1_2_13_304_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.10212"},{"key":"e_1_2_13_305_1","doi-asserted-by":"publisher","DOI":"10.1369\/jhc.4A6585.2005"},{"key":"e_1_2_13_306_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI111546"},{"key":"e_1_2_13_307_1","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2011.199"},{"key":"e_1_2_13_308_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13669"},{"key":"e_1_2_13_309_1","doi-asserted-by":"publisher","DOI":"10.4161\/derm.1.2.8472"},{"key":"e_1_2_13_310_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2015.070"},{"key":"e_1_2_13_311_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.2004.04216.x"},{"key":"e_1_2_13_312_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.01-0487fje"},{"key":"e_1_2_13_313_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16436"},{"key":"e_1_2_13_314_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12676783"},{"key":"e_1_2_13_315_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1962.10"},{"key":"e_1_2_13_316_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1962.146"},{"key":"e_1_2_13_317_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1963.131"},{"key":"e_1_2_13_318_1","doi-asserted-by":"publisher","DOI":"10.1016\/0196-9781(81)90024-3"},{"key":"e_1_2_13_319_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2009.02.061"},{"key":"e_1_2_13_320_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(65)80277-3"},{"key":"e_1_2_13_321_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2003-1728"},{"key":"e_1_2_13_322_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12512337"},{"key":"e_1_2_13_323_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6102.1581"},{"key":"e_1_2_13_324_1","doi-asserted-by":"publisher","DOI":"10.1290\/1071-2690(2001)037<0050:PEOCRH>2.0.CO;2"},{"key":"e_1_2_13_325_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14494"},{"key":"e_1_2_13_326_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1982.tb01031.x"},{"key":"e_1_2_13_327_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2003.032284"},{"key":"e_1_2_13_328_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1967.179"},{"key":"e_1_2_13_329_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201798280"},{"issue":"1","key":"e_1_2_13_330_1","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1242\/jcs.95.1.125","article-title":"Organ maintenance of human sebaceous glands: in vitro effects of 13\u2010cis retinoic acid and testosterone","volume":"95","author":"Ridden J.","year":"1990","journal-title":"Journal of Cell Science"},{"key":"e_1_2_13_331_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700305"},{"key":"e_1_2_13_332_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2016.05.113"},{"key":"e_1_2_13_333_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S137794"},{"key":"e_1_2_13_334_1","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.12.03.287"},{"key":"e_1_2_13_335_1","doi-asserted-by":"publisher","DOI":"10.1159\/000017864"},{"key":"e_1_2_13_336_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0625.2003.00014.x"},{"key":"e_1_2_13_337_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13752"},{"key":"e_1_2_13_338_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12340934"},{"key":"e_1_2_13_339_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2008.06.116"},{"key":"e_1_2_13_340_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.1114"},{"key":"e_1_2_13_341_1","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.32.1504"},{"key":"e_1_2_13_342_1","first-page":"559","article-title":"Serum prolactin in normal and pathologic pregnancy","volume":"50","author":"Sadovsky E.","year":"1977","journal-title":"Obstetrics and Gynecology"},{"key":"e_1_2_13_343_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2009.06.037"},{"key":"e_1_2_13_344_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12551679"},{"key":"e_1_2_13_345_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.014225"},{"key":"e_1_2_13_346_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2017.09.024"},{"key":"e_1_2_13_347_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0022-202x.2001.01516.x"},{"key":"e_1_2_13_348_1","doi-asserted-by":"publisher","DOI":"10.1159\/000382031"},{"key":"e_1_2_13_349_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12541229"},{"key":"e_1_2_13_350_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.104588"},{"key":"e_1_2_13_351_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12664"},{"key":"e_1_2_13_352_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2015.11.008"},{"key":"e_1_2_13_353_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2009.11.017"},{"key":"e_1_2_13_354_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-014-1999-1"},{"key":"e_1_2_13_355_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-015-1599-2"},{"key":"e_1_2_13_356_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13513"},{"key":"e_1_2_13_357_1","doi-asserted-by":"publisher","DOI":"10.1099\/ijsem.0.001367"},{"key":"e_1_2_13_358_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.1998.00358.x"},{"key":"e_1_2_13_359_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-1281(97)80024-4"},{"key":"e_1_2_13_360_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1957.87"},{"key":"e_1_2_13_361_1","doi-asserted-by":"publisher","DOI":"10.3371\/CSRP.5.3.4"},{"key":"e_1_2_13_362_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00185300"},{"key":"e_1_2_13_363_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)49094-1"},{"key":"e_1_2_13_364_1","first-page":"847","article-title":"Use of intradermal botulinum toxin to reduce sebum production and facial pore size","volume":"7","author":"Shah A. R.","year":"2008","journal-title":"Journal of Drugs in Dermatology"},{"key":"e_1_2_13_365_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.08.015"},{"key":"e_1_2_13_366_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12676782"},{"key":"e_1_2_13_367_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-61779-536-7_1"},{"key":"e_1_2_13_368_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08958.x"},{"key":"e_1_2_13_369_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(96)01315-4"},{"key":"e_1_2_13_370_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4165(95)00159-X"},{"key":"e_1_2_13_371_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.83.3.1020"},{"key":"e_1_2_13_372_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.81.7.2746"},{"key":"e_1_2_13_373_1","doi-asserted-by":"publisher","DOI":"10.1067\/mlc.2000.110605"},{"key":"e_1_2_13_374_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1996.tb05049.x"},{"key":"e_1_2_13_375_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01923606"},{"key":"e_1_2_13_376_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2003-0851"},{"key":"e_1_2_13_377_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.85.2.815"},{"key":"e_1_2_13_378_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.21.5.457"},{"key":"e_1_2_13_379_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2002.19617.x"},{"key":"e_1_2_13_380_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.2000.80.3.979"},{"key":"e_1_2_13_381_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.00-0850rev"},{"key":"e_1_2_13_382_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2006.12.012"},{"key":"e_1_2_13_383_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.20530"},{"key":"e_1_2_13_384_1","doi-asserted-by":"publisher","DOI":"10.2741\/1966"},{"key":"e_1_2_13_385_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1999.tb08686.x"},{"key":"e_1_2_13_386_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2017.10.025"},{"key":"e_1_2_13_387_1","doi-asserted-by":"publisher","DOI":"10.1290\/1071-2690(2000)036<0211:CRHARP>2.0.CO;2"},{"key":"e_1_2_13_388_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2017-03230"},{"key":"e_1_2_13_389_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-19683-6_1"},{"key":"e_1_2_13_390_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.2012-1092"},{"key":"e_1_2_13_391_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12293"},{"key":"e_1_2_13_392_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.R700015-JLR200"},{"key":"e_1_2_13_393_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2007.11.005"},{"key":"e_1_2_13_394_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.01.046"},{"key":"e_1_2_13_395_1","doi-asserted-by":"publisher","DOI":"10.31887\/DCNS.2006.8.4\/ssmith"},{"key":"e_1_2_13_396_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700278"},{"key":"e_1_2_13_397_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1184733"},{"key":"e_1_2_13_398_1","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.000299"},{"key":"e_1_2_13_399_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2010.125"},{"key":"e_1_2_13_400_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2005.01.007"},{"key":"e_1_2_13_401_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02505253"},{"key":"e_1_2_13_402_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.1998.1998015253.x"},{"key":"e_1_2_13_403_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1959.112"},{"key":"e_1_2_13_404_1","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20187437"},{"key":"e_1_2_13_405_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1971.tb14048.x"},{"key":"e_1_2_13_406_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1972.tb05077.x"},{"key":"e_1_2_13_407_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1971.tb02556.x"},{"key":"e_1_2_13_408_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1976.tb04340.x"},{"key":"e_1_2_13_409_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)65078-X"},{"key":"e_1_2_13_410_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1969.100"},{"key":"e_1_2_13_411_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2018.07.015"},{"key":"e_1_2_13_412_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1983.tb01138.x"},{"key":"e_1_2_13_413_1","first-page":"157","article-title":"Ultrastructure of the sebaceous glands of the camel (Camelus dromedarius)","volume":"156","author":"Taha A. A. M.","year":"1988","journal-title":"Journal of Anatomy"},{"key":"e_1_2_13_414_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12393"},{"key":"e_1_2_13_415_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18071447"},{"key":"e_1_2_13_416_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13462"},{"key":"e_1_2_13_417_1","first-page":"27","article-title":"The role of inflammation in the pathology of acne","volume":"6","author":"Tanghetti E. A.","year":"2013","journal-title":"The Journal of Clinical and Aesthetic Dermatology"},{"key":"e_1_2_13_418_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2006.02631.x"},{"key":"e_1_2_13_419_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2000.00094.x"},{"key":"e_1_2_13_420_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0710279"},{"key":"e_1_2_13_421_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12543511"},{"key":"e_1_2_13_422_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0490325"},{"key":"e_1_2_13_423_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0480139"},{"key":"e_1_2_13_424_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0500533"},{"key":"e_1_2_13_425_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0490329"},{"key":"e_1_2_13_426_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0540239"},{"key":"e_1_2_13_427_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0640503"},{"key":"e_1_2_13_428_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1989.69.2.383"},{"key":"e_1_2_13_429_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1985.tb15265.x"},{"key":"e_1_2_13_430_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0890225"},{"key":"e_1_2_13_431_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0198323"},{"key":"e_1_2_13_432_1","doi-asserted-by":"publisher","DOI":"10.1159\/000067818"},{"key":"e_1_2_13_433_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0625.2002.110307.x"},{"key":"e_1_2_13_434_1","first-page":"422","article-title":"Neuropeptides and sebaceous glands","volume":"12","author":"Toyoda M.","year":"2002","journal-title":"European Journal of Dermatology"},{"key":"e_1_2_13_435_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-018-0345-x"},{"key":"e_1_2_13_436_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(72)90446-2"},{"key":"e_1_2_13_437_1","first-page":"340","article-title":"Small\u2010nodular sebaceous gland hypertrophy after cortisone treatment of Addison's disease","volume":"33","author":"Undeutsch W.","year":"1962","journal-title":"Zeitschrift f\u00fcr Haut\u2010 und Geschlechtskrankheiten"},{"key":"e_1_2_13_438_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.286"},{"key":"e_1_2_13_439_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1989.tb03843.x"},{"key":"e_1_2_13_440_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08764.x"},{"key":"e_1_2_13_441_1","doi-asserted-by":"publisher","DOI":"10.1186\/1742-2094-9-181"},{"key":"e_1_2_13_442_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e31816421fd"},{"key":"e_1_2_13_443_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(03)00083-3"},{"key":"e_1_2_13_444_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjp.2008.185"},{"key":"e_1_2_13_445_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M310529200"},{"key":"e_1_2_13_446_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2010.01199.x"},{"key":"e_1_2_13_447_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01243521"},{"key":"e_1_2_13_448_1","doi-asserted-by":"publisher","DOI":"10.1159\/000069757"},{"key":"e_1_2_13_449_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1959.138"},{"key":"e_1_2_13_450_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10286-002-0025-y"},{"key":"e_1_2_13_451_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00408228"},{"key":"e_1_2_13_452_1","doi-asserted-by":"publisher","DOI":"10.1002\/sctm.18-0037"},{"key":"e_1_2_13_453_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-018-00417-3"},{"key":"e_1_2_13_454_1","doi-asserted-by":"publisher","DOI":"10.1210\/me.2012-1297"},{"key":"e_1_2_13_455_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.10567"},{"key":"e_1_2_13_456_1","doi-asserted-by":"publisher","DOI":"10.1530\/acta.0.0830711"},{"key":"e_1_2_13_457_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplegacy.1975.229.4.1102"},{"key":"e_1_2_13_458_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13772"},{"key":"e_1_2_13_459_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2010.12.020"},{"key":"e_1_2_13_460_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2018.04.019"},{"key":"e_1_2_13_461_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0231"},{"key":"e_1_2_13_462_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06794.x"},{"key":"e_1_2_13_463_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.137075"},{"key":"e_1_2_13_464_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2018.02.022"},{"key":"e_1_2_13_465_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(01)01476-X"},{"key":"e_1_2_13_466_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1747.2003.12612.x"},{"key":"e_1_2_13_467_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.181R001"},{"key":"e_1_2_13_468_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.20209"},{"key":"e_1_2_13_469_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700607"},{"key":"e_1_2_13_470_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2003.tb03175.x"},{"key":"e_1_2_13_471_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2005.05.030"},{"key":"e_1_2_13_472_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2010.10.100"},{"key":"e_1_2_13_473_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000001181"},{"key":"e_1_2_13_474_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00414-012-0741-3"},{"key":"e_1_2_13_475_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2006.00191.x"},{"key":"e_1_2_13_476_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408440601123446"},{"key":"e_1_2_13_477_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2016.12.009"},{"key":"e_1_2_13_478_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12298"},{"key":"e_1_2_13_479_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.102180999"}],"container-title":["Biological Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbrv.12579","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/brv.12579","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/brv.12579","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/brv.12579","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T22:16:13Z","timestamp":1694038573000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/brv.12579"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,22]]},"references-count":478,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["10.1111\/brv.12579"],"URL":"https:\/\/doi.org\/10.1111\/brv.12579","archive":["Portico"],"relation":{},"ISSN":["1464-7931","1469-185X"],"issn-type":[{"value":"1464-7931","type":"print"},{"value":"1469-185X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,22]]},"assertion":[{"value":"2019-05-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-12-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}