{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T05:49:54Z","timestamp":1773294594863,"version":"3.50.1"},"reference-count":46,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,7,15]],"date-time":"2013-07-15T00:00:00Z","timestamp":1373846400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["acamh.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Child Adoles Ment Health"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study investigates changes in metabolic parameters in prepubertal children after 14\u201316 weeks of treatment with low\u2010dose risperidone.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Thirty\u2010one children (mean age 5.46\u00a0\u00b1\u00a01.98\u00a0years) were treated with risperidone (0.25\u20131\u00a0mg\/day; 0.01\u20130.07\u00a0mg\/kg\/day). Patients were excluded if they were using any medication other than risperidone or were diagnosed with any medical problem in addition to a non\u2010psychotic disorder.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Weight (\u0394: 2.51\u00a0\u00b1\u00a01.94\u00a0kg), height (\u0394: 0.03\u00a0\u00b1\u00a00.04\u00a0cm),\n                      <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>\n                      (\u0394: 0.82\u00a0\u00b1\u00a01.4),\n                      <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>\n                      percentile (\u0394: 9.72\u00a0\u00b1\u00a016.40),\n                      <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>\n                      z\u2010score (\u0394: 0.33\u00a0\u00b1\u00a01.03), triglyceride (\u0394: 1.50\u00a0\u00b1\u00a023.97\u00a0mg\/dl), very low density lipoprotein (\u0394: 2.99\u00a0\u00b1\u00a04.76\u00a0mg\/dl), insulin (\u0394: 3.07\u00a0\u00b1\u00a03.38\u00a0mIU\/ml), and leptin (\u0394: 3.02\u00a0\u00b1\u00a04.69\u00a0ng\/ml) were significantly increased (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The metabolic side effects of risperidone must be carefully monitored in prepubertal children.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/camh.12033","type":"journal-article","created":{"date-parts":[[2013,7,15]],"date-time":"2013-07-15T08:26:49Z","timestamp":1373876809000},"page":"20-25","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Change in metabolic parameters and weight in response to risperidone monotherapy in young children with nonpsychotic disorders: a prospective open\u2010label study"],"prefix":"10.1111","volume":"20","author":[{"given":"Burcu Ersoz","family":"Alan","sequence":"first","affiliation":[{"name":"Child and Adolescent Psychiatry Clinic Dr. Sami Ulus Women and Children's Health and Diseases Training and Research Hospital Telsizler\/Altindag Ankara 06080 Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. 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