{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T01:16:14Z","timestamp":1791162974192,"version":"4.1.0"},"reference-count":57,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,6,21]],"date-time":"2013-06-21T00:00:00Z","timestamp":1371772800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer Science"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:p>\n                    The relationship between consumption of cruciferous vegetables (\n                    <jats:styled-content style=\"fixed-case\">CV<\/jats:styled-content>\n                    ) and risk of gastric cancer has been investigated by many studies, but remains controversial. We carried out a meta\u2010analysis to summarize available evidence from epidemiological studies on this point. Relevant published reports of\n                    <jats:styled-content style=\"fixed-case\">CV<\/jats:styled-content>\n                    intake and gastric cancer were identified using\n                    <jats:styled-content style=\"fixed-case\">MEDLINE<\/jats:styled-content>\n                    (\n                    <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\n                    ub\n                    <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>\n                    ed),\n                    <jats:styled-content style=\"fixed-case\">EMBASE<\/jats:styled-content>\n                    , and\n                    <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>\n                    eb of\n                    <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>\n                    cience databases through to the end of\n                    <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>\n                    eptember 2012. We pooled the relative risk from individual studies using a fixed\u2010 or random\u2010effects model and carried out heterogeneity and publication bias analyses. Sixteen case\u2013control and six prospective studies were included in our analysis. When all studies were pooled, we yielded a significantly inverse association between\n                    <jats:styled-content style=\"fixed-case\">CV<\/jats:styled-content>\n                    (relative risk\u00a0=\u00a00.81; 95% confidence interval, 0.75\u20130.88) intake and gastric cancer risk, with little heterogeneity (\n                    <jats:italic>Q\u00a0<\/jats:italic>\n                    =\u00a027.27,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00.292,\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u00a0=\u00a012.0%). Specific analysis for cabbage intake yielded similar result. When separately analyzed, case\u2013control studies of\n                    <jats:styled-content style=\"fixed-case\">CV<\/jats:styled-content>\n                    intake yielded significant results and the results of prospective studies showed borderline statistical significance. Moreover, significant results were consistent for high\u2010quality studies, for North American,\n                    <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>\n                    uropean, and\n                    <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\n                    sian studies, for studies on males, and for studies on non\u2010cardia gastric cancer. Findings from this meta\u2010analysis provide evidence that high intake of\n                    <jats:styled-content style=\"fixed-case\">CV<\/jats:styled-content>\n                    was inversely associated with the risk of gastric cancer and non\u2010cardia gastric cancer in humans. Further studies on other specific\n                    <jats:styled-content style=\"fixed-case\">CV<\/jats:styled-content>\n                    , food preparation methods, and stratified results by anatomic cancer site and histological type should be extended in the future.\n                  <\/jats:p>","DOI":"10.1111\/cas.12195","type":"journal-article","created":{"date-parts":[[2013,5,16]],"date-time":"2013-05-16T04:33:07Z","timestamp":1368678787000},"page":"1067-1073","source":"Crossref","is-referenced-by-count":96,"title":["Cruciferous vegetable consumption and gastric cancer risk: A meta\u2010analysis of epidemiological studies"],"prefix":"10.1111","volume":"104","author":[{"given":"Qi\u2010Jun","family":"Wu","sequence":"first","affiliation":[{"name":"State Key Laboratory of Oncogene and Related Genes Shanghai Cancer Institute Renji Hospital Shanghai Jiaotong University School of Medicine Shanghai China"},{"name":"Department of Epidemiology Shanghai Cancer Institute Renji Hospital Shanghai Jiaotong University School of Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Yang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oncogene and Related Genes Shanghai Cancer Institute Renji Hospital Shanghai Jiaotong University School of Medicine Shanghai China"},{"name":"Department of Epidemiology Shanghai Cancer Institute Renji Hospital Shanghai Jiaotong University School of Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oncogene and Related Genes Shanghai Cancer Institute Renji Hospital Shanghai Jiaotong University School of Medicine Shanghai China"},{"name":"Department of Epidemiology Shanghai Cancer Institute Renji Hospital Shanghai Jiaotong University School of Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li\u2010Hua","family":"Han","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oncogene and Related Genes Shanghai Cancer Institute Renji Hospital Shanghai Jiaotong University School of Medicine Shanghai China"},{"name":"Department of Epidemiology Shanghai Cancer Institute Renji Hospital Shanghai Jiaotong University School of Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong\u2010Bing","family":"Xiang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oncogene and Related Genes Shanghai Cancer Institute Renji Hospital Shanghai Jiaotong University School of Medicine Shanghai China"},{"name":"Department of Epidemiology Shanghai Cancer Institute Renji Hospital Shanghai Jiaotong University School of Medicine Shanghai 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