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Recent sequencing studies have clarified the recurrent mutations in ras homology family member A (\n                    <jats:italic>\n                      <jats:styled-content style=\"fixed-case\">RHOA<\/jats:styled-content>\n                    <\/jats:italic>\n                    ) and in genes encoding epigenetic regulators, tet methyl cytosine dioxygenase 2 (\n                    <jats:italic>\n                      <jats:styled-content style=\"fixed-case\">TET<\/jats:styled-content>\n                      2\n                    <\/jats:italic>\n                    ),\n                    <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content>\n                    methyl transferase 3 alpha (\n                    <jats:italic>\n                      <jats:styled-content style=\"fixed-case\">DNMT<\/jats:styled-content>\n                      3A\n                    <\/jats:italic>\n                    ) and\n                    <jats:italic>isocitrate dehydrogenase 2<\/jats:italic>\n                    ,\n                    <jats:italic>mitochondrial<\/jats:italic>\n                    (\n                    <jats:italic>\n                      <jats:styled-content style=\"fixed-case\">IDH<\/jats:styled-content>\n                      2\n                    <\/jats:italic>\n                    ), as well as those related to the T\u2010cell receptor signaling pathway in\n                    <jats:styled-content style=\"fixed-case\">AITL<\/jats:styled-content>\n                    . In this review, we focus on how this genetic information has changed the understanding of the developmental process of\n                    <jats:styled-content style=\"fixed-case\">AITL<\/jats:styled-content>\n                    and will in future lead to individualized therapies for\n                    <jats:styled-content style=\"fixed-case\">AITL<\/jats:styled-content>\n                    patients.\n                  <\/jats:p>","DOI":"10.1111\/cas.13393","type":"journal-article","created":{"date-parts":[[2017,9,10]],"date-time":"2017-09-10T07:32:40Z","timestamp":1505028760000},"page":"490-496","source":"Crossref","is-referenced-by-count":43,"title":["Review of the biologic and clinical significance of genetic mutations in angioimmunoblastic T\u2010cell lymphoma"],"prefix":"10.1111","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2729-5780","authenticated-orcid":false,"given":"Kota","family":"Fukumoto","sequence":"first","affiliation":[{"name":"Department of 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