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In particular,\n                    <jats:styled-content style=\"fixed-case\">PDPN<\/jats:styled-content>\n                    increases tumor cell clonal capacity, epithelial mesenchymal transition, migration, invasion, metastasis and inflammation. Antibodies,\n                    <jats:styled-content style=\"fixed-case\">CAR<\/jats:styled-content>\n                    \u2010T cells, biologics and synthetic compounds that target\n                    <jats:styled-content style=\"fixed-case\">PDPN<\/jats:styled-content>\n                    can inhibit cancer progression and septic inflammation in preclinical models. This review describes recent advances in how\n                    <jats:styled-content style=\"fixed-case\">PDPN<\/jats:styled-content>\n                    may be used as a biomarker and therapeutic target for many types of cancer, including glioma, squamous cell carcinoma, mesothelioma and melanoma.\n                  <\/jats:p>","DOI":"10.1111\/cas.13580","type":"journal-article","created":{"date-parts":[[2018,3,25]],"date-time":"2018-03-25T09:36:44Z","timestamp":1521970604000},"page":"1292-1299","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":183,"title":["Podoplanin: An emerging cancer biomarker and therapeutic target"],"prefix":"10.1111","volume":"109","author":[{"given":"Harini","family":"Krishnan","sequence":"first","affiliation":[{"name":"Department of Physiology and Biophysics Stony Brook University Stony Brook NY 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