{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T15:40:58Z","timestamp":1787586058470,"version":"build-2736575974"},"reference-count":50,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,9,9]],"date-time":"2020-09-09T00:00:00Z","timestamp":1599609600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Science"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Skin cancer is the most frequently diagnosed cancer in the fair\u2010skinned population. In recent years, the incidence of nonmelanoma skin cancer (NMSC) has been increasing worldwide. However, there is no epidemiological study on skin cancer in the Asian population. A prospective cohort study including 140\u00a0420 participants was initiated in 1990 for cohort \u2160 and 1993 for cohort \u2161 at baseline survey from 11 public health center (PHC) areas. Of these participants, 284 NMSC cases were diagnosed during the follow\u2010up period (through 2012 in the Osaka PHC area and 2013 in the other PHC areas). The Cox proportional hazards model was used to estimate hazard ratios and 95% confidence intervals (CI) for NMSC incidence according to occupational type, lifestyle factors (alcohol consumption, coffee consumption, smoking status, physical activity, and body mass index), and family history of cancer. Among men, compared with indoor workers, outdoor workers were associated with 2.18 (95% CI, 1.17\u20104.04) higher risk of squamous cell carcinoma (SCC) but not of basal cell carcinoma (BCC). Furthermore, men who have a family history of cancer had 1.99 (95% CI, 1.10\u20103.62) higher SCC risk. In women, we did not observe any association between occupational type and the risk of SCC (1.26; 95% CI, 0.68\u20102.32) or BCC (0.74; 95% CI, 0.42\u20101.28). In conclusion, men who are outdoor workers or have a family history of cancer had an increased risk of SCC.<\/jats:p>","DOI":"10.1111\/cas.14619","type":"journal-article","created":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T13:26:59Z","timestamp":1598621219000},"page":"4257-4265","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Epidemiology of nonmelanoma skin cancer in Japan: Occupational type, lifestyle, and family history of cancer"],"prefix":"10.1111","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7831-6764","authenticated-orcid":false,"given":"Honglin","family":"Cai","sequence":"first","affiliation":[{"name":"Department of Environmental Medicine and Population Sciences Graduate School of Medicine Osaka University Suita 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