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This prespecified subanalysis of the Cancer\u2010VTE Registry aimed to report venous thromboembolism and event data after 1\u2009year of follow\u2010up in 2477 patients with colorectal cancer and investigate risk factors of venous thromboembolism. Of 2477 patients, 158 (6.4%) had venous thromboembolism in venous thromboembolism screening at enrollment. Asymptomatic distal deep\u2010vein thrombosis accounted for 123\/158 (77.8%) of venous thromboembolism cases. During the follow\u2010up period, symptomatic, incidental events requiring treatment and composite venous thromboembolism incidences were 0.3%, 0.8%, and 1.0%, respectively. The incidence of bleeding events, cerebral infarction\/transient ischemic attack\/systemic embolic event, and all\u2010cause death were 1.0%, 0.3%, and 4.8%, respectively. These results were consistent with the main study results. In multivariable analysis, venous thromboembolism at baseline was a risk factor of composite venous thromboembolism during the follow\u2010up period. Japanese patients with colorectal cancer and advancing cancer stage before treatment had more frequent venous thromboembolism complications at baseline, higher incidence of venous thromboembolism events during cancer treatment, and higher mortality.<\/jats:p>","DOI":"10.1111\/cas.15527","type":"journal-article","created":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T16:19:36Z","timestamp":1660148376000},"page":"3901-3911","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Incidence and risk factors for venous thromboembolism, bleeding, and death in colorectal cancer (<scp>C<\/scp>ancer\u2010<scp>VTE<\/scp> Registry)"],"prefix":"10.1111","volume":"113","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9602-6659","authenticated-orcid":false,"given":"Masataka","family":"Ikeda","sequence":"first","affiliation":[{"name":"Division of Lower Gastrointestinal Surgery, Department of Gastroenterological Surgery Hyogo Medical University  Nishinomiya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Uetake","sequence":"additional","affiliation":[{"name":"Department of Clinical Research National Hospital Organization Disaster Medical Center  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0489-4756","authenticated-orcid":false,"given":"Takayuki","family":"Yoshino","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology National Cancer Center Hospital East  Kashiwa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taishi","family":"Hata","sequence":"additional","affiliation":[{"name":"Department of Surgery Kansai Rosai Hospital Japan Organization of Occupational Health and Safety  Amagasaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mari S.","family":"Oba","sequence":"additional","affiliation":[{"name":"Department of Medical Statistics Toho University  Tokyo Japan"},{"name":"Department of Clinical Data Science, Clinical Research &amp; Education Promotion Division National Center of Neurology and Psychiatry  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Takita","sequence":"additional","affiliation":[{"name":"Data Intelligence Department Daiichi Sankyo Co., Ltd.  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