{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:49:07Z","timestamp":1747183747650,"version":"3.40.5"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,4,23]],"date-time":"2023-04-23T00:00:00Z","timestamp":1682208000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["15H04774"],"award-info":[{"award-number":["15H04774"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Science"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A causal relationship between mesothelioma and occupational asbestos exposure is well known, while some studies have shown a relationship to non\u2010occupational exposures. The aim of this study was to quantify the risk of mesothelioma death associated with neighborhood asbestos exposure due to a large\u2010scale asbestos\u2010cement (AC) plant in Amagasaki, Japan, adjusting properly risk factors including occupational exposures. We conducted a nested case\u2010control study in which a fixed population of 143,929 residents who had been living in Amagasaki City between 1975 and 2002 were followed from 2002 to 2015. All 133 cases and 403 matched controls were interviewed about their occupational, domestic, household, and neighborhood asbestos exposures. Odds ratios (ORs) for mesothelioma death associated with the neighborhood exposure were estimated by a conditional logistic\u2010regression model. For quantitative assessments for neighborhood exposure, we adopted cumulative indices for individuals' residential histories at each residence\u2010specific asbestos concentration multiplied by the duration during the potential exposure period of 1957\u20131975 (crocidolite). We observed an increasing, dose\u2010dependent risk of mesothelioma death associated with neighborhood exposure, demonstrating that ORs in the highest quintile category were 21.4 (95% confidence interval [CI] 5.8\u201379.2) for all, 23.7 (95% CI 3.8\u2013147.2) for males, and 26.0 (95% CI 2.8\u2013237.5) for females compared to the lowest quintile, respectively. A quantitative assessment for risk of mesothelioma deaths, adjusting for occupational and non\u2010occupational exposures separately, showed a dose\u2010dependent association with neighborhood exposure and no substantial gender differences in magnitude.<\/jats:p>","DOI":"10.1111\/cas.15802","type":"journal-article","created":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T12:15:12Z","timestamp":1680524112000},"page":"2973-2985","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Association of mesothelioma deaths with neighborhood asbestos exposure due to a large\u2010scale asbestos\u2010cement plant"],"prefix":"10.1111","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7665-3524","authenticated-orcid":false,"given":"Yuri","family":"Kitamura","sequence":"first","affiliation":[{"name":"Department of Social Medicine Osaka University Graduate School of Medicine  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Zha","sequence":"additional","affiliation":[{"name":"Department of Social Medicine Osaka University Graduate School of Medicine  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Social Medicine Osaka University Graduate School of Medicine  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayuki","family":"Shima","sequence":"additional","affiliation":[{"name":"Department of Public Health Hyogo Medical University  Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoki","family":"Nakaya","sequence":"additional","affiliation":[{"name":"Department of Frontier Sciences for Advanced Environment, Graduate School of Environmental Studies Tohoku University  Sendai Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norio","family":"Kurumatani","sequence":"additional","affiliation":[{"name":"Department of Community Health and Epidemiology Nara Medical University School of Medicine  Kashihara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Kumagai","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Management University of Occupational and Environmental Health  Kitakyushu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junko","family":"Goji","sequence":"additional","affiliation":[{"name":"Amagasaki City Health and Welfare Center  Amagasaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2817-3483","authenticated-orcid":false,"given":"Tomotaka","family":"Sobue","sequence":"additional","affiliation":[{"name":"Department of Social Medicine Osaka University Graduate School of Medicine  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,4,23]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"260","article-title":"Diffuse pleural mesothelioma and asbestos exposure in the North Western Cape Province","volume":"17","author":"Wagner JC","year":"1960","journal-title":"Br J Ind Med"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.99107s2289"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/oem.54.6.403"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.157.1.96-11086"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)90034-M"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1054\/bjoc.2000.1161"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12940-018-0431-9"},{"key":"e_1_2_10_9_1","unstructured":"OshimaH.Five cases with mesothelioma living near a now\u2010defunct asbestos cement plant in Amagasaki City (in Japan). In:Mainichi Newspaper.2005."},{"key":"e_1_2_10_10_1","unstructured":"Kubota\u2010Corporation.Demographic data of employees with asbestos\u2010related diseases in Kanzaki Plant a now\u2010defunct asbestos cement plant in Amagasaki City Hyogo (in Japan). Accessed 2005.2005."},{"key":"e_1_2_10_11_1","unstructured":"Amagasaki\u2010City.A report on the amount of asbestos used in the past by 136 companies in Amagasaki City Hyogo (in Japan).2006; 6:207\u2010213. Accessed 2006."},{"key":"e_1_2_10_12_1","unstructured":"Survey report on the health effects of asbestos in Hyogo prefecture.2006. Accessed March 20 2023.https:\/\/www.env.go.jp\/press\/files\/jp\/8032.pdf"},{"key":"e_1_2_10_13_1","unstructured":"Mesothelioma death subscript surevey report from 2008\u20132012 2013\u20132015 and 2002\u20132015.2018. 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