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This study aimed to clarify trends in the treatment and survival of CRC using population\u2010based cancer registry data in Japan. We analyzed the survival of CRC cases diagnosed from 1995 through 2015 from a population\u2010based cancer registry of six prefectures. The year of diagnosis was classified into five periods, and the trends in the detailed categorization of treatments and survival were identified. We calculated net survival and excess hazard of death from cancer using data on 256,590 CRC patients. The use of laparoscopic surgery has been increasing since 2005 and accounts for the largest proportion of treatment types in the most recent period. Net survival of CRC patients diagnosed after 2005 remained high for laparoscopic surgery and endoscopic surgery (endoscopic mucosal resection or endoscopic submucosal dissection). There was an upward trend in treatment with chemotherapy in addition to open and laparoscopic surgery. Using the excess hazard ratio at the regional stage since 2005, there has been a significant improvement in survival in the younger age group and the rectum cancer group. By type of treatment, there was a tendency toward significant improvement in the open surgery + chemotherapy group. We clarified the trends in treating CRC and the associated trends in survival. Continuous survey based on population\u2010based data helps monitor the impact of developments in treatment.<\/jats:p>","DOI":"10.1111\/cas.16210","type":"journal-article","created":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T05:45:23Z","timestamp":1715147123000},"page":"2786-2794","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Trends in patterns of treatment and survival of colorectal cancer patients using cancer registry data in Japan: 1995\u20132015"],"prefix":"10.1111","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4338-6380","authenticated-orcid":false,"given":"Masato","family":"Ota","sequence":"first","affiliation":[{"name":"Department of General and Gastroenterological Surgery Osaka Medical and Pharmaceutical University  Takatsuki Japan"},{"name":"Center for Medical Research &amp; Development, Division of Translational Research Osaka Medical and Pharmaceutical University  Takatsuki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0648-1370","authenticated-orcid":false,"given":"Kohei","family":"Taniguchi","sequence":"additional","affiliation":[{"name":"Translational Research Program Osaka Medical and Pharmaceutical University  Takatsuki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megumi","family":"Hori","sequence":"additional","affiliation":[{"name":"School of Nursing University of Shizuoka  Shizuoka City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kota","family":"Katanoda","sequence":"additional","affiliation":[{"name":"National Cancer Center Institute for Cancer Control  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9782-8637","authenticated-orcid":false,"given":"Kayo","family":"Nakata","sequence":"additional","affiliation":[{"name":"Cancer Control Center, Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isao","family":"Miyashiro","sequence":"additional","affiliation":[{"name":"Cancer Control Center, Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7311-1233","authenticated-orcid":false,"given":"Tomohiro","family":"Matsuda","sequence":"additional","affiliation":[{"name":"National Cancer Center Institute for Cancer Control  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang\u2010Woong","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of General and Gastroenterological Surgery Osaka Medical and Pharmaceutical University  Takatsuki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1407-2393","authenticated-orcid":false,"given":"Yuri","family":"Ito","sequence":"additional","affiliation":[{"name":"Center for Medical Research &amp; Development, Division of Translational Research Osaka Medical and Pharmaceutical University  Takatsuki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,5,7]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"Cancer Information Service NCC Japan (Vital Statistics of Japan Ministry of Health Labour and Welfare). 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