{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T09:32:45Z","timestamp":1787563965367,"version":"build-2736575974"},"reference-count":29,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,10,25]],"date-time":"2012-10-25T00:00:00Z","timestamp":1351123200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chem Biol Drug Des"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:p>\n                    The coumarin compounds are an important class of biologically active molecules, which have attractive caught the attention of many organic and medicinal chemists, due to potential pharmaceutical implications and industrial applications. We herein report the one\u2010pot procedure for the efficient synthesis of coumarin derivatives using commercially available substrates\n                    <jats:italic>via<\/jats:italic>\n                    isocyanide\u2010based multicomponent condensation reactions. These compounds were evaluated for anti\u2010mycobacterium activity against\n                    <jats:italic>Mycobacterium bovis<\/jats:italic>\n                    (\n                    <jats:italic>Bacillus Calmette\u2013Guerin<\/jats:italic>\n                    ). The preliminary results indicated that all of the tested compounds showed relatively good activity against the test organism. The compounds\n                    <jats:bold>7e<\/jats:bold>\n                    ,\n                    <jats:bold>7l<\/jats:bold>\n                    , and\n                    <jats:bold>7m<\/jats:bold>\n                    showed high anti\u2010tuberculosis activity.\n                  <\/jats:p>","DOI":"10.1111\/cbdd.12044","type":"journal-article","created":{"date-parts":[[2012,9,3]],"date-time":"2012-09-03T11:55:15Z","timestamp":1346673315000},"page":"929-936","source":"Crossref","is-referenced-by-count":21,"title":["Synthesis and Biological Evaluation of Coumarin Derivatives as Inhibitors of\n                    <i>Mycobacterium bovis<\/i>\n                    (BCG)"],"prefix":"10.1111","volume":"80","author":[{"given":"Ali Hossein","family":"Rezayan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parisa","family":"Azerang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soroush","family":"Sardari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afshin","family":"Sarvary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,10,25]]},"reference":[{"key":"e_1_2_5_2_2","unstructured":"XuZ.\u2010Q. 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