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This convergence of foundational principles and cutting\u2010edge innovations positions platinum therapy for a transformative era, promising enhanced precision, efficacy, and equity in cancer care worldwide.\n                  <\/jats:p>","DOI":"10.1111\/cbdd.70208","type":"journal-article","created":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T08:36:18Z","timestamp":1765010178000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Platinum\u2010Based Chemotherapeutics in the Modern Era: From Classical\n                    <scp>DNA<\/scp>\n                    \u2010Targeting Mechanisms to Next\u2010Generation Innovations in Cancer Therapy"],"prefix":"10.1111","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4651-7975","authenticated-orcid":false,"given":"Mohammad Bagher","family":"Shahsavani","sequence":"first","affiliation":[{"name":"Protein Chemistry Laboratory (PCL) Institute of Biochemistry and Biophysics (IBB), University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahsa","family":"Heidari","sequence":"additional","affiliation":[{"name":"Protein Chemistry Laboratory (PCL) Institute of Biochemistry and Biophysics (IBB), University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Yousefi","sequence":"additional","affiliation":[{"name":"Protein Chemistry Laboratory (PCL) Institute of Biochemistry and Biophysics (IBB), University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Akbar","family":"Moosavi\u2010Movahedi","sequence":"additional","affiliation":[{"name":"Institute of Biochemistry and Biophysics (IBB), University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,6]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10534-020-00235-3"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/slct.202401566"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers16203522"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2024.116211"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-21-0407"},{"key":"e_1_2_15_7_1","unstructured":"Agennix.2012.\u201cA Multi\u2010National Phase III Study of Satraplatin Plus Prednisone or Placebo Plus Prednisone in Patients With Hormone Refractory Prostate Cancer Previously Treated With One Cytotoxic Chemotherapy Regimen Clinicaltrials.gov.\u201dhttps:\/\/clinicaltrials.gov\/study\/NCT00069745."},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/07853890.2024.2305308"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.2174\/156800910791190175"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/nano13101619"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2024.110066"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032709"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11725-011-0275-8"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.4c01093"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2011.04.012"},{"key":"e_1_2_15_16_1","first-page":"877","article-title":"Satraplatin in the Treatment of Hormone\u2010Refractory Metastatic Prostate Cancer","volume":"3","author":"Armstrong A. 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