{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T23:47:04Z","timestamp":1777506424677,"version":"3.51.4"},"reference-count":39,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,5,7]],"date-time":"2017-05-07T00:00:00Z","timestamp":1494115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Office of Medical Education at the University of Rochester School of Medicine","award":["OME Summer International Award"],"award-info":[{"award-number":["OME Summer International Award"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Child"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The Ages and Stages Questionnaires Edition 3 (ASQ\u20103) are a well\u2010validated international screen for developmental delays in young children. However, previous studies demonstrate variable scores between children eligible to take the same ASQ\u20103 interval. This study aimed to determine a relationship between age and ASQ\u20103 score for each screening interval.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a baseline exploratory cross\u2010sectional study of infants under 2\u00a0years old evaluated for the Peruvian social programme <jats:italic>Cuna M\u00e1s<\/jats:italic>. Participants were included in <jats:italic>Cuna M\u00e1s<\/jats:italic> if they lived in districts with fewer than 2000 inhabitants or 400 homes, indicating a predominantly rural population. The appropriate ASQ\u20103 screening interval was administered to each subject. Subjects were divided into four 2\u2010week chronological subgroups based on age within each 2\u2010month screening window and aggregated across all 12 screening intervals. Fisher's exact test, analysis of variance and Bonferonni <jats:italic>post hoc<\/jats:italic> test were used to compare differences between age subgroups. Linear regression was performed to assess the relationship between ASQ\u20103 score and both aggregated and disaggregated age subgroup.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 5850 Peruvian infants were evaluated in 2013. Mean age was 13\u00a0\u00b1\u00a06.6\u00a0months, 50.7% were male and mean maternal education was 6.6\u00a0\u00b1\u00a04.0\u00a0years; 34.8% infants were stunted, 7.8% were underweight, 0.9% were wasted and 2% had age adjusted greater than 35\u00a0days for prematurity for ASQ\u20103 interval assignment. Mean total ASQ\u20103 was 42.2\u00a0\u00b1\u00a08.2. The ASQ\u20103 allocated 49.6% with suspected delay in one or more developmental areas.<\/jats:p><jats:p>Before and after adjusting for wealth quintile, maternal education level, infant nutritional status and prematurity adjustment, age subgroup remained significantly associated with total ASQ\u20103 score (<jats:italic>\u03b2<\/jats:italic>\u00a0=\u00a01.8, CI: 1.7\u20132.0, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), sectional ASQ\u20103 score (all <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and inversely associated with one or more scores indicating suspected developmental delay (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The ASQ\u20103 may underestimate the sensitivity of child development to small differences in age in this population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cch.12469","type":"journal-article","created":{"date-parts":[[2017,5,8]],"date-time":"2017-05-08T02:20:52Z","timestamp":1494210052000},"page":"556-565","source":"Crossref","is-referenced-by-count":17,"title":["ASQ\u20103 scores are sensitive to small differences in age in a Peruvian infant population"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9038-0304","authenticated-orcid":false,"given":"K. 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E.","family":"Vel\u00e1squez\u2010Hurtado","sequence":"additional","affiliation":[{"name":"Ministry of Development and Social Inclusion  Lima Peru"},{"name":"School of Medicine, School of Public Health Universidad Peruana Cayetano Heredia  Lima Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Sadeghi","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine University of Rochester  Rochester NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Llanos","sequence":"additional","affiliation":[{"name":"Ministry of Development and Social Inclusion  Lima Peru"},{"name":"School of Medicine, School of Public Health Universidad Peruana Cayetano Heredia  Lima Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,5,7]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2015.10.001"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2016.04.004"},{"key":"e_1_2_8_4_1","doi-asserted-by":"crossref","unstructured":"Barnett W.1995. 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