{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T11:51:54Z","timestamp":1779105114066,"version":"3.51.4"},"reference-count":43,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,7,14]],"date-time":"2017-07-14T00:00:00Z","timestamp":1499990400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002848","name":"Comisi\u00f3n Nacional de Investigaci\u00f3n Cient\u00edfica y Tecnol\u00f3gica","doi-asserted-by":"publisher","award":["1130387"],"award-info":[{"award-number":["1130387"]}],"id":[{"id":"10.13039\/501100002848","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Child"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Most studies on functional gastrointestinal disorders (FGIDs) in children are based on data from the northern hemisphere. Scientific reports are arising in South American population, but little is still known about children from low socio\u2010economic status (SES), where<jats:italic>Helicobacter pylori<\/jats:italic>infection is endemic. Our objective was to evaluate the prevalence of FGIDs in school children from low SES and its relationship with<jats:italic>H. pylori<\/jats:italic>infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Children from 3 public schools of low SES from Santiago de Chile were included. Students completed the Rome III Questionnaire and a survey about other symptoms. Also, the<jats:sup>13<\/jats:sup>C urea breath test determined the presence of<jats:italic>H. pylori<\/jats:italic>infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Five hundred six children were included, where 48% were male, with a median age of 15.7\u00a0years (range 7.1\u201319.6). Forty\u2010two percent had some FGID, aerophagia and functional constipation being the most frequent. Females (adjusted OR 1.5, 95% CI [1.1, 2.2]), those children with parents within the lowest level of education (adjusted OR 1.6, 95% CI: 1.1\u20132.4), and family history of gastric cancer (adjusted OR 1.9, 95% CI: 1.2\u20133.1) were related to FGIDs. The prevalence of<jats:italic>H. pylori<\/jats:italic>infection was 55.9% (95% CI [50.7, 60.9]). In multivariable analysis, the presence of abdominal pain (OR 1.55, 95% CI [1.02, 2.36]), but not FGIDs, was related to<jats:italic>H. pylori<\/jats:italic>infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>FGIDs are common in low SES students. A low educational level of the household head, family history of gastric cancer. and being female are related to the development of FGIDs. In this study, no relationship between the presence of<jats:italic>H. pylori<\/jats:italic>and FGIDs was found.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cch.12486","type":"journal-article","created":{"date-parts":[[2017,7,14]],"date-time":"2017-07-14T07:22:37Z","timestamp":1500016957000},"page":"319-325","source":"Crossref","is-referenced-by-count":16,"title":["Functional gastrointestinal disorders in children from low socio\u2010economic status and<i>Helicobacter pylori<\/i>infection"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8411-8537","authenticated-orcid":false,"given":"F.","family":"Jaime","sequence":"first","affiliation":[{"name":"Department of Pediatric Gastroenterology and Nutrition School of Medicine, Pontificia Universidad Cat\u00f3lica de Chile Santiago Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Villagr\u00e1n","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology and Nutrition School of Medicine, Pontificia Universidad Cat\u00f3lica de Chile Santiago Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology and Nutrition School of Medicine, Pontificia Universidad Cat\u00f3lica de Chile Santiago Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Ortiz","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology and Nutrition School of Medicine, Pontificia Universidad Cat\u00f3lica de Chile Santiago Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Serrano","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology and Nutrition School of Medicine, Pontificia Universidad Cat\u00f3lica de Chile Santiago Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. 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