{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T10:28:06Z","timestamp":1775816886095,"version":"3.50.1"},"reference-count":55,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,5,21]],"date-time":"2019-05-21T00:00:00Z","timestamp":1558396800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["MOP\u2010133645"],"award-info":[{"award-number":["MOP\u2010133645"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Child"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Evidence suggests that physical and mental illnesses are strongly correlated in children. This study examined patterns of the chronicity of multimorbidity (co\u2010occurring physical and mental illness); estimated homotypic continuity; and modelled factors associated with chronicity in children newly diagnosed with a chronic physical illness.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Children aged 6\u201316\u00a0years diagnosed with one of asthma, diabetes, epilepsy, food allergy, or juvenile arthritis were recruited from two children's hospitals and followed for 6\u00a0months. Child mental illness was measured using the parent\u2010reported Mini International Neuropsychiatric Interview and Ontario Child Health Study Emotional Behavioural Scales at baseline and 6\u00a0months later. Children were stratified into three groups: no multimorbidity, acute (multimorbidity at only one assessment), and persistent (multimorbidity at both assessments).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010nine children were available for analysis: no multimorbidity (<jats:italic>n<\/jats:italic>\u00a0=\u00a018), acute (<jats:italic>n<\/jats:italic>\u00a0=\u00a013), and persistent (<jats:italic>n<\/jats:italic>\u00a0=\u00a018). Homotypic continuity was highest for conduct disorder (67.5%) and lowest for major depression (16.7%). Unadjusted analyses showed positive associations between child and parent behavioural symptoms, as well as family functioning with persistent multimorbidity. These associations remained after adjustment, ranging from odds ratio (OR)\u00a0=\u00a01.29 [1.01, 1.64] for depression to OR\u00a0=\u00a01.61 [1.11, 2.33] and OR\u00a0=\u00a01.61 [1.10, 2.35] for attention\u2010deficit hyperactivity and oppositional defiant, respectively, in child models. In parent models, associations remained for parental anxiety (OR\u00a0=\u00a01.18 [1.04, 1.34]) and stress (OR\u00a0=\u00a01.15 [1.02, 1.31]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Multimorbidity is persistent in children newly diagnosed with physical illnesses, regardless of the mental comorbidity experienced. Integrating family\u2010centred mental health services soon after the diagnosis of a physical illness should be prioritized in pediatric settings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cch.12667","type":"journal-article","created":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T02:19:42Z","timestamp":1555294782000},"page":"559-567","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Chronicity of mental comorbidity in children with new\u2010onset physical illness"],"prefix":"10.1111","volume":"45","author":[{"given":"Shannon V.","family":"Reaume","sequence":"first","affiliation":[{"name":"School of Public Health and Health Systems University of Waterloo  Waterloo Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0979-3233","authenticated-orcid":false,"given":"Mark A.","family":"Ferro","sequence":"additional","affiliation":[{"name":"School of Public Health and Health Systems University of Waterloo  Waterloo Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,5,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0265407595123009"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2005.07.013"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/mpr.1544"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0706743718808251"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.1993.tb00979.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2012.09.017"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-019011"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc14-0262"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1545-5300.1988.00097.x"},{"issue":"5","key":"e_1_2_7_11_1","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1542\/peds.90.5.692","article-title":"Mental disorders in chronically ill children: Parent\u2010child discrepancy and physician identification","volume":"90","author":"Canning E. H.","year":"1992","journal-title":"Pediatrics"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech.2009.103887"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.60.8.837"},{"issue":"5","key":"e_1_2_7_14_1","first-page":"706","article-title":"Visual Analogue Scale (VAS)","volume":"10","author":"Crichton N.","year":"2001","journal-title":"Journal of Clinical Nursing"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.131.4.483"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1037\/pas0000541"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0706743718808250"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/00393541.2007.11518721"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.12429"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00127-015-1103-5"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1017\/S2045796015000700"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0031861"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10802-014-9893-6"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1037\/hea0000226"},{"key":"e_1_2_7_25_1","article-title":"Mental\u2010physical multimorbidity in youth: Associations with individual, family, and health service use outcomes","author":"Ferro M. A.","year":"2018","journal-title":"Child Psychiatry and Human Development"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00737-013-0331-5"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12829"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.3109\/02770903.2015.1104694"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291712001754"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579411000538"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/nur.20247"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.2005.01456.x"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199912000-00019"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acap.2017.02.002"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199901000-00020"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1525-5050(03)00007-6"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1998.tb09546.x"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1177\/1049732314540339"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-1444"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1177\/1059840516641190"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.2466\/pr0.1996.79.3.1059"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1177\/1049732309338722"},{"issue":"3","key":"e_1_2_7_43_1","first-page":"245","article-title":"Bullying involvement of children with and without chronic physical illness and\/or physical\/sensory disability\u2014A meta\u2010analytic comparison with healthy\/nondisabled peers","volume":"42","author":"Pinquart M.","year":"2017","journal-title":"Journal of Pediatric Psychology"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.12381"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1080\/02673843.2017.1297242"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acap.2014.08.004"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1177\/014662167700100306"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-007-9240-2"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.09m05305whi"},{"key":"e_1_2_7_50_1","volume-title":"State\u2010Trait Anxiety Inventory for adults","author":"Spielberger C. D.","year":"1983"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.153.1.68"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0000000000000151"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0165196"},{"key":"e_1_2_7_54_1","unstructured":"World Health Organization(2016).Noncommunicable diseases. Retrieved fromhttps:\/\/www.who.int\/en\/news\u2010room\/fact\u2010sheets\/detail\/noncommunicable\u2010diseases"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-015-0514-5"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/fare.12306"}],"container-title":["Child: Care, Health and Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcch.12667","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cch.12667","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cch.12667","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cch.12667","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T17:13:23Z","timestamp":1694366003000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cch.12667"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,21]]},"references-count":55,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1111\/cch.12667"],"URL":"https:\/\/doi.org\/10.1111\/cch.12667","archive":["Portico"],"relation":{},"ISSN":["0305-1862","1365-2214"],"issn-type":[{"value":"0305-1862","type":"print"},{"value":"1365-2214","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,21]]},"assertion":[{"value":"2018-12-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}