{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T13:05:00Z","timestamp":1792155900951,"version":"4.4.0"},"reference-count":54,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,9,22]],"date-time":"2023-09-22T00:00:00Z","timestamp":1695340800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Child"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Despite numerous studies on early child development, there is still much to be discovered about the significance of possible risk factors. This study examines cognitive, motor, and language development of healthy children growing up in a low\u2010risk environment and how various individual and environmental factors are associated with it. The study also considers whether the importance of particular parameters changes depending on child age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Within the framework of the LIFE Child study in Leipzig, Germany, 481 children participated in a total of 832 visits between 1 and 36\u2009months of age. Developmental status was assessed using the Third Edition of the Bayley Scales of Infant and Toddler Development. Linear regression analyses were applied to examine the associations between child development and sex, gestational age, birth weight, birth mode, overweight, height, and parental education.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Mean Bayley composite scores for cognitive, language, and motor development were close to the standard value of 100. Poorer developmental outcomes were significantly associated with lower gestational age, vacuum cup\/forceps birth, being overweight, small height, and lower parental education, although some of the associations became insignificant after applying multivariate models. While the association between gestational age and language development became weaker with advancing age, our interaction models found disparities related to parental education to become more apparent in older children across all three domains of early child development.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Several factors were identified to be associated with early child development. As children grow older, obstetric parameters, for example, gestational age, might become less relevant compared with sociodemographic factors, for example, parental education.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cch.13177","type":"journal-article","created":{"date-parts":[[2023,9,22]],"date-time":"2023-09-22T07:29:14Z","timestamp":1695367754000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Early child development and its determinants: Findings from a large cohort of healthy children growing up in a low\u2010risk environment"],"prefix":"10.1111","volume":"50","author":[{"given":"Jonas","family":"Kappelt","sequence":"first","affiliation":[{"name":"LIFE Leipzig Research Center for Civilization Diseases Leipzig University  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christof","family":"Meigen","sequence":"additional","affiliation":[{"name":"LIFE Leipzig Research Center for Civilization Diseases Leipzig University  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara Elise","family":"Schild","sequence":"additional","affiliation":[{"name":"LIFE Leipzig Research Center for Civilization Diseases Leipzig University  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wieland","family":"Kiess","sequence":"additional","affiliation":[{"name":"LIFE Leipzig Research Center for Civilization Diseases Leipzig University  Leipzig Germany"},{"name":"Department of Women and Children's Health, Hospital for Children and Adolescents and Center for Pediatric Research (CPL) Leipzig University  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3825-5829","authenticated-orcid":false,"given":"Tanja","family":"Poulain","sequence":"additional","affiliation":[{"name":"LIFE Leipzig Research Center for Civilization Diseases Leipzig University  Leipzig Germany"},{"name":"Department of Women and Children's Health, Hospital for Children and Adolescents and Center for Pediatric Research (CPL) Leipzig University  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,9,22]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.11.015"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.14832"},{"key":"e_1_2_11_4_1","unstructured":"Arbeitsgemeinschaft Adipositas im Kindes\u2010 und Jugendalter (AGA) der Deutschen Adipositas\u2010Gesellschaft (DAG) und der Deutschen Gesellschaft f\u00fcr Kinder\u2010und Jugendmedizin (DGKJ). 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