{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T15:12:38Z","timestamp":1791817958075,"version":"4.3.4"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T00:00:00Z","timestamp":1735862400000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Child"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Malaria remains a major cause of preventable deaths among children worldwide, despite the availability of several interventions for controlling and eliminating the disease. The WHO recommended the first malaria vaccine, RTS, S\/AS01 in October 2021 to immunize children in sub\u2010Saharan Africa. In this study, we set out to evaluate the knowledge, awareness and acceptability of the malaria vaccine among mothers of under 5 in south\u2010west Nigeria before the vaccine's rollout in Nigeria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We employed a hospital\u2010based cross\u2010sectional study for this study. A pretested semistructured, interviewer\u2010administered questionnaire was used to elicit information from the study participants. Data obtained were analysed using the Statistical Package for Social Sciences (SPSS version 20.0).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 797 respondents participated in the study. Only 26.0% of the respondents were aware of the new vaccine. However, the majority (90.0%) were willing to accept the malaria vaccination and to pay for it (82.1%). The crude odds ratio reveals that the odds of awareness of the malaria vaccine were more than 5 times higher among those who have tertiary education (OR\u2009=\u20095.470, CI\u2009=\u20091.224\u201324.444) compared with those with primary education.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The level of awareness of the malarial vaccine is low among the caregivers of under 5 children living in south\u2010western Nigeria. However, the willingness to accept the vaccine is high. Recruiting, training and retraining of healthcare providers and other stakeholders with the designated role of providing health education on malaria prevention and vaccines are key in ensuring the success of malaria vaccination.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cch.70029","type":"journal-article","created":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T09:35:49Z","timestamp":1735896949000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Awareness, Acceptability and Factors Influencing Malaria Vaccine Uptake Among Caregivers of Children Under 5 in South\u2010Western Nigeria"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6503-6416","authenticated-orcid":false,"given":"Adeleke\u00a0Thomas","family":"Olumide","sequence":"first","affiliation":[{"name":"Family Medicine Department Bowen University  Iwo Osun State Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oboh\u00a0Mary","family":"Aigbiremo","sequence":"additional","affiliation":[{"name":"Microbiology Department Bowen University  Iwo Osun State Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olasinde","family":"Yetunde","sequence":"additional","affiliation":[{"name":"Paediatric Department Bowen University  Iwo Osun State Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akinlosotu\u00a0Morenike","family":"Agnes","sequence":"additional","affiliation":[{"name":"Paediatric Department University of Medical Sciences  Ondo City Ondo State Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oluwasanya\u00a0Alarape","family":"Naomi","sequence":"additional","affiliation":[{"name":"Family Medicine Department Olabisi Onabanjo University Teaching Hospital  Sagamu Ogun State Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adeleke\u00a0Oludamola","family":"Victoria","sequence":"additional","affiliation":[{"name":"Department of Nursing Bowen University  Iwo Osun State Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy\u00a0Kayode","family":"Samson","sequence":"additional","affiliation":[{"name":"Statistics Programme Bowen University  Iwo Osun State Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,3]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/fmad001"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12936\u2010023\u201004768\u2010z"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12936\u2010022\u201004164\u2010z"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12936\u2010018\u20102335\u20100"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/14760584.2023.2292204"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1002380"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0040073"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12936-020-3141-z"},{"key":"e_1_2_11_10_1","doi-asserted-by":"crossref","unstructured":"Musa\u2010BoothT. O. B. E.Enobun A. J.Agbomola C. J.Shiff.2020. \u201cKnowledge Attitude and Willingness to Accept the RTS S Malaria Vaccine Among Mothers in Abuja Nigeria.\u201d Medrxiv. December 4 2020\u201012.","DOI":"10.1101\/2020.12.03.20242784"},{"key":"e_1_2_11_11_1","unstructured":"National Bureau of Statistics (NBS).2018. \u201cNigeria's Demographic and Health Survey 2018.\u201d Abuja: National Bureau of Statistics. Accessed November 5 2023."},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/23311983.2020.1799483"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2007.01961.x"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2010.10.008"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines10071008"},{"key":"e_1_2_11_16_1","unstructured":"WHO.2018. \u201cTowards a Global Action Plan for Healthy Lives and Well\u2010Being for all.\u201d Geneva: World Health Organization."},{"key":"e_1_2_11_17_1","unstructured":"WHO.2021. \u201cWHO Approves First Malaria Vaccine: Why Did It Take so Long?\u201d"},{"key":"e_1_2_11_18_1","unstructured":"WHO.2023. \u201cR21\/Matrix\u2010M Vaccine for Malaria Prevention in Updated Advice on Immunization.\u201d WHO: Geneva Switzerland."},{"key":"e_1_2_11_19_1","unstructured":"World Health Organization.2023. \u201cWorld Malaria Report 2023.\u201d World Health Organization. November 30 2023."}],"container-title":["Child: Care, Health and Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cch.70029","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T06:14:38Z","timestamp":1738304078000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cch.70029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1111\/cch.70029"],"URL":"https:\/\/doi.org\/10.1111\/cch.70029","archive":["Portico"],"relation":{},"ISSN":["0305-1862","1365-2214"],"issn-type":[{"value":"0305-1862","type":"print"},{"value":"1365-2214","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2024-07-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70029"}}