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This study included 165 adolescents (ages 14\u201317 years) selected based on their reactivity to novelty at 4 months. Infant attachment was assessed with the Strange Situation. Multimethod BI assessments were conducted across childhood. Adolescents and their parents independently reported on anxiety. The interaction of attachment and BI significantly predicted adolescent anxiety symptoms, such that BI and anxiety were only associated among adolescents with histories of insecure attachment. Exploratory analyses revealed that this effect was driven by insecure-resistant attachment and that the association between BI and social anxiety was significant only for insecure males. Clinical implications are discussed.<\/jats:p>","DOI":"10.1111\/cdev.12336","type":"journal-article","created":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T01:47:27Z","timestamp":1418953647000},"page":"598-613","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":66,"title":["Infant Attachment Security and Early Childhood Behavioral Inhibition Interact to Predict Adolescent Social Anxiety Symptoms"],"prefix":"10.1093","volume":"86","author":[{"given":"Erin","family":"Lewis-Morrarty","sequence":"first","affiliation":[{"name":"University of Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn A","family":"Degnan","sequence":"additional","affiliation":[{"name":"University of Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Chronis-Tuscano","sequence":"additional","affiliation":[{"name":"University of Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel S","family":"Pine","sequence":"additional","affiliation":[{"name":"National Institute of Mental Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather A","family":"Henderson","sequence":"additional","affiliation":[{"name":"University of Waterloo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan A","family":"Fox","sequence":"additional","affiliation":[{"name":"University of Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2015,3,25]]},"reference":[{"key":"2026010916062360800_cdev12336-cit-0001","volume-title":"Multiple regression: Testing and interpreting interactions","author":"Aiken","year":"1991"},{"key":"2026010916062360800_cdev12336-cit-0002","volume-title":"Patterns of attachment: Psychological study of the Strange Situation","author":"Ainsworth","year":"1978"},{"key":"2026010916062360800_cdev12336-cit-0003","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1111\/1469-7610.00622","article-title":"Stability and change of attachment at 14, 24, and 58 months of age: Behavior, representation, and life events","volume":"41","author":"Bar-Haim","year":"2000","journal-title":"Journal of Child Psychology and Psychiatry"},{"key":"2026010916062360800_cdev12336-cit-0004","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1111\/j.1467-8624.2011.01712.x","article-title":"Enhancing attachment organization among maltreated children: Results of a randomized clinical trial","volume":"83","author":"Bernard","year":"2012","journal-title":"Child Development"},{"key":"2026010916062360800_cdev12336-cit-0005","doi-asserted-by":"publisher","first-page":"1230","DOI":"10.1097\/00004583-199910000-00011","article-title":"Psychometric properties of the Screen for Child Anxiety Related Emotional Disorders (SCARED): A replication study","volume":"38","author":"Birmaher","year":"1999","journal-title":"Journal of the American Academy of Child & Adolescent Psychiatry"},{"key":"2026010916062360800_cdev12336-cit-0006","volume-title":"Attachment and loss: Vol. I. 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