{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T15:49:03Z","timestamp":1748620143213,"version":"3.40.5"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Comm Dent Oral Epid"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study aimed to identify studies exploring oral and systemic conditions using Singapore data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Studies were searched using the databases PubMed, Embase and Web of Science, with no publication date or language restrictions. Studies analysing Singaporean data were included in this review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Six domains were identified: pregnancy and gingivitis; tooth eruption, dental caries and early\u2010life factors; Crohn's disease and oral microbiome; diabetes and periodontal diseases; number of teeth, chewing ability and cognitive status; and oral health and pneumonia. Using data from Singapore, oral\u2010systemic studies have prompted reflections on the aetiopathogenesis of oral disorders, such as common causes connecting oral and systemic chronic conditions. Moreover, it is speculated whether oral conditions could be used as a marker to predict future systemic diseases or whether early\u2010life factors could affect the development of oral and systemic immune responses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>While Singapore provides opportunities to explore challenges connected to healthy ageing, it also explores health development in many stages of life. Singapore has been prioritizing investigations on a healthier life, and new initiatives are paving the way for oral health research across the lifespan.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cdoe.12913","type":"journal-article","created":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T06:14:58Z","timestamp":1696227298000},"page":"353-363","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Oral and systemic health in Singapore: Revisiting the past to define the future"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4288-6300","authenticated-orcid":false,"given":"Gustavo G.","family":"Nascimento","sequence":"first","affiliation":[{"name":"National Dental Centre Singapore National Dental Research Institute Singapore  Singapore Singapore"},{"name":"Oral Health Academic Clinical Programme Duke\u2010NUS Medical School  Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8400-8808","authenticated-orcid":false,"given":"Preethi","family":"Balan","sequence":"additional","affiliation":[{"name":"National Dental Centre Singapore National Dental Research Institute Singapore  Singapore Singapore"},{"name":"Oral Health Academic Clinical Programme Duke\u2010NUS Medical School  Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7982-5301","authenticated-orcid":false,"given":"Silas","family":"Alves\u2010Costa","sequence":"additional","affiliation":[{"name":"National Dental Centre Singapore National Dental Research Institute Singapore  Singapore Singapore"},{"name":"Graduate Dentistry Program Federal University of Maranh\u00e3o  S\u00e3o Lu\u00eds Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7310-2767","authenticated-orcid":false,"given":"Fernando Valentim","family":"Bitencourt","sequence":"additional","affiliation":[{"name":"Department of Dentistry and Oral Health Aarhus University  Aarhus Denmark"},{"name":"Steno Diabetes Center Aarhus  Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2800-1486","authenticated-orcid":false,"given":"Ashish C.","family":"Kalhan","sequence":"additional","affiliation":[{"name":"National Dental Centre Singapore National Dental Research Institute Singapore  Singapore Singapore"},{"name":"Oral Health Academic Clinical Programme Duke\u2010NUS Medical School  Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8053-4517","authenticated-orcid":false,"given":"Fabio R. 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