{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T06:05:27Z","timestamp":1788588327286,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T00:00:00Z","timestamp":1704672000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T00:00:00Z","timestamp":1704672000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Comm Dent Oral Epid"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This multicentre, assessor\u2010blinded, two\u2010arm cluster randomized trial evaluated the clinical and cost\u2010effectiveness of a behaviour change intervention promoting toothbrushing for preventing dental caries in UK secondary schools.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Pupils aged 11\u201313\u2009years with their own mobile telephone attending secondary schools with above average free school meals eligibility were randomized (at year\u2010group level) to receive a lesson and twice\u2010daily text messages or to usual care. Year\u2010groups (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200984) from 42 schools including 4680 pupils (intervention,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20092262; control,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20092418) were randomized.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In 2383 participants with valid data at baseline and 2.5\u2009years, the primary outcome of presence of at least one treated or untreated carious lesion (D\n                      <jats:sub>4\u20106<\/jats:sub>\n                      MFT [Decayed, Missing and Filled Teeth] in permanent teeth using International Caries Detection and Assessment System) was 44.6% in the intervention group and 43.0% in control (odds ratio [OR] 1.04, 95% CI 0.85\u20131.26,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.72). There were no statistically significant differences in secondary outcomes of presence of at least one treated or untreated carious lesion (D\n                      <jats:sub>1\u20106<\/jats:sub>\n                      MFT), number of D\n                      <jats:sub>4\u20106<\/jats:sub>\n                      MFT and D\n                      <jats:sub>1\u20106<\/jats:sub>\n                      MFT, plaque and bleeding scores or health\u2010related\u2010 (Child Health Utility 9D) or oral health\u2010related\u2010 quality of life (CARIES\u2010QC). However, twice\u2010daily toothbrushing, reported by 77.6% of pupils at baseline, increased at 6\u2009months (intervention, 86.9%; control, 83.0%; OR 1.30, 95% CI 1.03\u20131.63,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.03), but returned to no difference at 2.5\u2009years (intervention, 81.0%; control, 79.9%; OR 1.05, 95% CI 0.84\u20131.30,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.69). Estimated incremental costs and quality\u2010adjusted life\u2010years (QALYs) of the intervention, relative to control, were \u00a31.02 (95% CI \u22121.29 to 3.23) and \u22120.003 (95% CI \u22120.009 to 0.002), respectively, with a 7% chance of being cost\u2010effective (\u00a320\u2009000\/QALY gained threshold).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>There was no evidence of statistically significant difference for caries prevalence at 2.5\u2010years. The intervention's positive 6\u2010month toothbrushing behaviour change did not translate into caries reduction. (ISRCTN 12139369). COVID\u201019 pandemic adversly affected follow\u2010up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cdoe.12940","type":"journal-article","created":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T08:17:40Z","timestamp":1704701860000},"page":"469-478","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Behaviour change intervention for toothbrushing (lesson and text messages) to prevent dental caries in secondary school pupils: The BRIGHT randomized control trial"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9984-0012","authenticated-orcid":false,"given":"Nicola","family":"Innes","sequence":"first","affiliation":[{"name":"School of Dentistry Cardiff University  Cardiff 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