{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:50:44Z","timestamp":1782211844010,"version":"3.54.5"},"reference-count":32,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["095582"],"award-info":[{"award-number":["095582"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004263","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado do Rio Grande do Sul","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004263","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007409","name":"Bernard van Leer Foundation","doi-asserted-by":"publisher","award":["BRA\u20102018\u2010178"],"award-info":[{"award-number":["BRA\u20102018\u2010178"]}],"id":[{"id":"10.13039\/100007409","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Comm Dent Oral Epid"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the association between prematurity and dental caries occurrence at four years of age and to assess whether variables related to dental development, tooth eruption, and oral healthcare mediate this association.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A longitudinal study was conducted using data from the 2015 Pelotas (RS) Birth Cohort. The outcome was dental caries at four years, classified using ICDAS. Gestational age at birth was estimated by ultrasonography examination in 3 407 (79.7%) cases, with 3 242 (75.8%) performed during the 1st or 2nd trimester. Mediating variables included enamel defects, number of teeth at 12\u2009months, oral hygiene practices, sugar consumption, and maternal guidance. The variables were selected using a directed acyclic graph (DAG). Associations were estimated using Poisson regression models, and mediation was assessed through structural equation modelling (SEM). Analyses were performed using STATA 18.0.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Children born before 34\u2009weeks had a 40% lower incidence of caries at four years compared to those born after 39\u2009weeks, and those born between 37 and 38\u2009weeks had a 20% lower incidence. The number of teeth mediated this relationship, indicating that lower gestational age was associated with fewer teeth at 12\u2009months and a lower occurrence of caries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The findings highlight the importance of early dental monitoring and suggest preventive programs starting with the eruption of the first tooth, given its relevance in the occurrence of caries.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cdoe.70086","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:35:17Z","timestamp":1782210917000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Effect of Prematurity on the Occurrence of Caries at Four Years of Age: A Prospective Cohort Study"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6819-3764","authenticated-orcid":false,"given":"Marina C.","family":"Rocha","sequence":"first","affiliation":[{"name":"Postgraduate Program in Epidemiology Federal University of Pelotas  Pelotas Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1082-0534","authenticated-orcid":false,"given":"Leticia R. M.","family":"Sartori","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Dentistry Federal University of Pelotas  Pelotas Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0467-3812","authenticated-orcid":false,"given":"Miguel K.","family":"Mascarenhas","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Epidemiology Federal University of Pelotas  Pelotas Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2503-2944","authenticated-orcid":false,"given":"Marlos R.","family":"Domingues","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Physical Education Federal University of Pelotas  Pelotas Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4680-3197","authenticated-orcid":false,"given":"Andr\u00e9a 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