{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T05:36:27Z","timestamp":1789623387733,"version":"build-2803163510"},"reference-count":42,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,12,14]],"date-time":"2016-12-14T00:00:00Z","timestamp":1481673600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Experimental Allergy"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Studies of children with food allergy typically only include the mother and have not investigated the relationship between the amount of allergen needed to elicit a clinical reaction (threshold) and health\u2010related quality of life (<jats:styled-content style=\"fixed-case\">HRQL<\/jats:styled-content>). Our aims were (i) to compare self\u2010reported and parent\u2010reported <jats:styled-content style=\"fixed-case\">HRQL<\/jats:styled-content> in different age groups, (ii) to evaluate the impact of severity of allergic reaction and threshold on <jats:styled-content style=\"fixed-case\">HRQL<\/jats:styled-content>, and (iii) to investigate factors associated with patient\u2010reported and parent\u2010reported <jats:styled-content style=\"fixed-case\">HRQL<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Age\u2010appropriate Food Allergy Quality of Life Questionnaires (<jats:styled-content style=\"fixed-case\">FAQLQ<\/jats:styled-content>) were completed by 73 children, 49 adolescents and 29 adults with peanut, hazelnut or egg allergy. Parents (197 mothers, 120 fathers) assessed their child's <jats:styled-content style=\"fixed-case\">HRQL<\/jats:styled-content> using the <jats:styled-content style=\"fixed-case\">FAQLQ<\/jats:styled-content>\u2010Parent form. Clinical data and threshold values were obtained from a hospital database. Significant factors for <jats:styled-content style=\"fixed-case\">HRQL<\/jats:styled-content> were investigated using univariate and multivariate regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Female patients reported greater impact of food allergy on <jats:styled-content style=\"fixed-case\">HRQL<\/jats:styled-content> than males did. Egg and hazelnut thresholds did not affect <jats:styled-content style=\"fixed-case\">HRQL<\/jats:styled-content>, but lower peanut threshold was associated with worse <jats:styled-content style=\"fixed-case\">HRQL<\/jats:styled-content>. Both parents scored their child's <jats:styled-content style=\"fixed-case\">HRQL<\/jats:styled-content> better than the child's own assessment, but whereas mother\u2010reported <jats:styled-content style=\"fixed-case\">HRQL<\/jats:styled-content> was significantly affected by limitations in the child's social life, father\u2010reported <jats:styled-content style=\"fixed-case\">HRQL<\/jats:styled-content> was affected by limitations in the family's social life. Severity of allergic reaction did not contribute significantly to <jats:styled-content style=\"fixed-case\">HRQL<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The risk of accidental allergen ingestion and limitations in social life are associated with worse <jats:styled-content style=\"fixed-case\">HRQL<\/jats:styled-content>. Fathers provide a unique perspective and should have a greater opportunity to contribute to food allergy research.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cea.12849","type":"journal-article","created":{"date-parts":[[2016,11,5]],"date-time":"2016-11-05T07:13:32Z","timestamp":1478330012000},"page":"530-539","source":"Crossref","is-referenced-by-count":99,"title":["Quality of life in childhood, adolescence and adult food allergy: Patient and parent perspectives"],"prefix":"10.1111","volume":"47","author":[{"given":"A.","family":"Stensgaard","sequence":"first","affiliation":[{"name":"Odense Research Center for Anaphylaxis (ORCA) Department of Dermatology and Allergy Center Odense University Hospital Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Bindslev\u2010Jensen","sequence":"additional","affiliation":[{"name":"Odense Research Center for Anaphylaxis (ORCA) Department of Dermatology and Allergy Center Odense University Hospital Odense 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